Jean-Claude Sirard

Directeur de recherche epst

U1019 - UMR 9017 - CENTRE D INFECTION ET D IMMUNITE DE LILLE - CIIL

Publications

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European Journal of Hospital Pharmacy, 2025, Eur J Hosp Pharm, <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/ejhpharm-2024-004441\">⟨10.1136/ejhpharm-2024-004441⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-05043532v1\">⟨hal-05043532⟩</a>", "title_s":["Physicochemical stability of a polysorbate-80-containing solvent compounded in the hospital pharmacy and used to reconstitute a biologic for nebulisation."], "authFullName_s":["Laura Negrier","Marine Roche","Damien Lannoy","C. Berneron","L. Pacqueu","Christophe Carnoy","A. Guillon","B. Hamzé","Jean-Claude Sirard","Bertrand Décaudin","Pascal Odou","Cecile Danel"], "halId_s":"hal-05043532", "docType_s":"ART", "producedDateY_i":2025 },{ "citationRef_s":"Antimicrobial Agents and Chemotherapy, 2024, Antimicrobial Agents and Chemotherapy, 68 (12), pp.e0086624. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/aac.00866-24\">⟨10.1128/aac.00866-24⟩</a>", "citationFull_s":"Mara Baldry, Yasmine Zeroual, Delphine Cayet, Jeoffrey Pardessus, Daphne Soulard, et al.. Targeted delivery of flagellin by nebulization offers optimized respiratory immunity and defense against pneumococcal pneumonia. Antimicrobial Agents and Chemotherapy, 2024, Antimicrobial Agents and Chemotherapy, 68 (12), pp.e0086624. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/aac.00866-24\">⟨10.1128/aac.00866-24⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-04840787v1\">⟨hal-04840787⟩</a>", "title_s":["Targeted delivery of flagellin by nebulization offers optimized respiratory immunity and defense against pneumococcal pneumonia"], "authFullName_s":["Mara Baldry","Yasmine Zeroual","Delphine Cayet","Jeoffrey Pardessus","Daphne Soulard","Frederic Wallet","Delphine Beury","David Hot","Ronan Macloughlin","Nathalie Heuzé-Vourc’h","Jean-Claude Sirard","Christophe Carnoy"], "halId_s":"hal-04840787", "docType_s":"ART", "producedDateY_i":2024 },{ "citationRef_s":"9. International Influenza Meeting:\" From bench to bedside\", Sep 2024, Münster (DE), Germany. <a target=\"_blank\" href=\"https://www.medizin.uni-muenster.de/fluresearchnet/events/9th-international-influenza-meeting.html\"></a>", "citationFull_s":"Elaa Chkhaydem, Isabelle Fleurot, Vanaïque Guillory, Emmanuel Kut, Céline Barc, et al.. Flagellin treatment: an immunomodulation strategy for controllong swine influenza infection. 9. International Influenza Meeting:\" From bench to bedside\", Sep 2024, Münster (DE), Germany. <a target=\"_blank\" href=\"https://www.medizin.uni-muenster.de/fluresearchnet/events/9th-international-influenza-meeting.html\"></a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-04913467v1\">⟨hal-04913467⟩</a>", "title_s":["Flagellin treatment: an immunomodulation strategy for controllong swine influenza infection"], "authFullName_s":["Elaa Chkhaydem","Isabelle Fleurot","Vanaïque Guillory","Emmanuel Kut","Céline Barc","Olivier Boulesteix","Alain Deslis","Alexis Pléau","Mara Baldry","Marie Couralet","Guillaume Beaumont","Jean-Claude Sirard","Pascal Barbry","Sascha Trapp","Ignacio Caballero-Posadas"], "halId_s":"hal-04913467", "docType_s":"POSTER", "producedDateY_i":2024 },{ "citationRef_s":"Journal of Infectious Diseases, 2024, pp.jiae239. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/infdis/jiae239\">⟨10.1093/infdis/jiae239⟩</a>", "citationFull_s":"Charlotte Costa, Jean-Claude Sirard, Paddy Gibson, Jan-Willem Veening, Erida Gjini, et al.. Triggering Toll-Like Receptor 5 Signaling During Pneumococcal Superinfection Prevents the Selection of Antibiotic Resistance. Journal of Infectious Diseases, 2024, pp.jiae239. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/infdis/jiae239\">⟨10.1093/infdis/jiae239⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-04605101v1\">⟨inserm-04605101⟩</a>", "title_s":["Triggering Toll-Like Receptor 5 Signaling During Pneumococcal Superinfection Prevents the Selection of Antibiotic Resistance"], "authFullName_s":["Charlotte Costa","Jean-Claude Sirard","Paddy Gibson","Jan-Willem Veening","Erida Gjini","Mara Baldry"], "halId_s":"inserm-04605101", "docType_s":"ART", "producedDateY_i":2024 },{ "citationRef_s":"Antimicrobial Agents and Chemotherapy, 2024, 68 (5), pp.e01361-23. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/aac.01361-23\">⟨10.1128/aac.01361-23⟩</a>", "citationFull_s":"Ana Raquel Maia, Adeline Cezard, Delphine Fouquenet, Virginie Vasseur, Benoit Briard, et al.. Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 2024, 68 (5), pp.e01361-23. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/aac.01361-23\">⟨10.1128/aac.01361-23⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04683300v1\">⟨hal-04683300⟩</a>", "title_s":["Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa"], "authFullName_s":["Ana Raquel Maia","Adeline Cezard","Delphine Fouquenet","Virginie Vasseur","Benoit Briard","Jean-Claude Sirard","Mustapha Si-Tahar","Virginie Hervé"], "halId_s":"hal-04683300", "docType_s":"ART", "producedDateY_i":2024 },{ "citationRef_s":"Cell Host & Microbe, 2024, 32 (3), pp.304-314.e8. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.chom.2024.02.002\">⟨10.1016/j.chom.2024.02.002⟩</a>", "citationFull_s":"Xue Liu, Laurye van Maele, Laura Matarazzo, Daphnée Soulard, Vinicius Alves Duarte da Silva, et al.. A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection. Cell Host & Microbe, 2024, 32 (3), pp.304-314.e8. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.chom.2024.02.002\">⟨10.1016/j.chom.2024.02.002⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-04605118v1\">⟨inserm-04605118⟩</a>", "title_s":["A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection"], "authFullName_s":["Xue Liu","Laurye van Maele","Laura Matarazzo","Daphnée Soulard","Vinicius Alves Duarte da Silva","Vincent de Bakker","Julien Dénéréaz","Florian Bock","Michael Taschner","Jinzhao Ou","Stephan Gruber","Victor Nizet","Jean-Claude Sirard","Jan-Willem Veening"], "halId_s":"inserm-04605118", "docType_s":"ART", "producedDateY_i":2024 },{ "citationRef_s":"International Journal of Molecular Sciences, 2023, 25 (1), pp.309. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/ijms25010309\">⟨10.3390/ijms25010309⟩</a>", "citationFull_s":"Christine van Linge, Katina Hulme, Hessel Peters-Sengers, Jean-Claude Sirard, Wil Goessens, et al.. Immunostimulatory Effect of Flagellin on MDR-Klebsiella-Infected Human Airway Epithelial Cells. International Journal of Molecular Sciences, 2023, 25 (1), pp.309. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/ijms25010309\">⟨10.3390/ijms25010309⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04462460v1\">⟨hal-04462460⟩</a>", "title_s":["Immunostimulatory Effect of Flagellin on MDR-Klebsiella-Infected Human Airway Epithelial Cells"], "authFullName_s":["Christine van Linge","Katina Hulme","Hessel Peters-Sengers","Jean-Claude Sirard","Wil Goessens","Menno de Jong","Colin Russell","Alex de Vos","Tom van der Poll"], "halId_s":"hal-04462460", "docType_s":"ART", "producedDateY_i":2023 },{ "citationRef_s":"Journal of Leukocyte Biology, 2023, Journal of Leukocyte Biology, 115 (3), pp.463-475. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/jleuko/qiad125\">⟨10.1093/jleuko/qiad125⟩</a>", "citationFull_s":"Melanie Mondeme, Yasmine Zeroual, Daphne Soulard, Benjamin Hennart, Delphine Beury, et al.. Amoxicillin treatment of pneumococcal pneumonia impacts bone marrow neutrophil maturation and function.. Journal of Leukocyte Biology, 2023, Journal of Leukocyte Biology, 115 (3), pp.463-475. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/jleuko/qiad125\">⟨10.1093/jleuko/qiad125⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-04474406v1\">⟨hal-04474406⟩</a>", "title_s":["Amoxicillin treatment of pneumococcal pneumonia impacts bone marrow neutrophil maturation and function."], "authFullName_s":["Melanie Mondeme","Yasmine Zeroual","Daphne Soulard","Benjamin Hennart","Delphine Beury","Jean-Michel Saliou","Christophe Carnoy","Jean-Claude Sirard","Christelle Faveeuw"], "halId_s":"hal-04474406", "docType_s":"ART", "producedDateY_i":2023 },{ "citationRef_s":"PLoS Biology, 2023, 21 (1), pp.e3001990. <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.pbio.3001990\">⟨10.1371/journal.pbio.3001990⟩</a>", "citationFull_s":"Vikrant Minhas, Arnau Domenech, Dimitra Synefiaridou, Daniel Straume, Max Brendel, et al.. Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence. PLoS Biology, 2023, 21 (1), pp.e3001990. <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.pbio.3001990\">⟨10.1371/journal.pbio.3001990⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04462466v1\">⟨hal-04462466⟩</a>", "title_s":["Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence"], "authFullName_s":["Vikrant Minhas","Arnau Domenech","Dimitra Synefiaridou","Daniel Straume","Max Brendel","Gonzalo Cebrero","Xue Liu","Charlotte Costa","Mara Baldry","Jean-Claude Sirard","Camilo Perez","Nicolas Gisch","Sven Hammerschmidt","Leiv Sigve Håvarstein","Jan-Willem Veening"], "halId_s":"hal-04462466", "docType_s":"ART", "producedDateY_i":2023 },{ "citationRef_s":"Infection and Immunity, 2023, 91 (2), pp.e00503-22. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/iai.00503-22\">⟨10.1128/iai.00503-22⟩</a>", "citationFull_s":"Mélanie Mondemé, Christophe Carnoy, Jean-Claude Sirard, Christelle Faveeuw. Treatment of Bacterial Infections with β-Lactams: Cooperation with Innate Immunity. Infection and Immunity, 2023, 91 (2), pp.e00503-22. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/iai.00503-22\">⟨10.1128/iai.00503-22⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04238526v1\">⟨hal-04238526⟩</a>", "title_s":["Treatment of Bacterial Infections with β-Lactams: Cooperation with Innate Immunity"], "authFullName_s":["Mélanie Mondemé","Christophe Carnoy","Jean-Claude Sirard","Christelle Faveeuw"], "halId_s":"hal-04238526", "docType_s":"ART", "producedDateY_i":2023 },{ "citationRef_s":"eLife, 2022, 11, <a target=\"_blank\" href=\"https://dx.doi.org/10.7554/eLife.75607\">⟨10.7554/eLife.75607⟩</a>", "citationFull_s":"Liselot Dewachter, Julien Dénéréaz, Xue Liu, Vincent de Bakker, Charlotte Costa, et al.. Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq. eLife, 2022, 11, <a target=\"_blank\" href=\"https://dx.doi.org/10.7554/eLife.75607\">⟨10.7554/eLife.75607⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04462473v1\">⟨hal-04462473⟩</a>", "title_s":["Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq"], "authFullName_s":["Liselot Dewachter","Julien Dénéréaz","Xue Liu","Vincent de Bakker","Charlotte Costa","Mara Baldry","Jean-Claude Sirard","Jan-Willem Veening"], "halId_s":"hal-04462473", "docType_s":"ART", "producedDateY_i":2022 },{ "citationRef_s":"Journal of Cystic Fibrosis, 2022, 21 (2), pp.e117-e121. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.jcf.2021.08.002\">⟨10.1016/j.jcf.2021.08.002⟩</a>", "citationFull_s":"Isabelle Fleurot, Raquel López-Gálvez, Pascal Barbry, Antoine Guillon, Mustapha Si-Tahar, et al.. TLR5 signalling is hyper-responsive in porcine cystic fibrosis airways epithelium. Journal of Cystic Fibrosis, 2022, 21 (2), pp.e117-e121. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.jcf.2021.08.002\">⟨10.1016/j.jcf.2021.08.002⟩</a>. <a target=\"_blank\" href=\"https://univ-tours.hal.science/hal-03556846v1\">⟨hal-03556846⟩</a>", "title_s":["TLR5 signalling is hyper-responsive in porcine cystic fibrosis airways epithelium"], "authFullName_s":["Isabelle Fleurot","Raquel López-Gálvez","Pascal Barbry","Antoine Guillon","Mustapha Si-Tahar","Andrea Bähr","Nikolai Klymiuk","Jean-Claude Sirard","Ignacio Caballero"], "halId_s":"hal-03556846", "docType_s":"ART", "producedDateY_i":2022 },{ "citationRef_s":"ImmunoHorizons , 2021, 5 (5), pp.273 - 283. <a target=\"_blank\" href=\"https://dx.doi.org/10.4049/immunohorizons.2000095\">⟨10.4049/immunohorizons.2000095⟩</a>", "citationFull_s":"Claire Mackowiak, Tiffany Marchiol, Hana Cipcic Paljetak, Louis Fauconnier, Jennifer Palomo, et al.. Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling. ImmunoHorizons , 2021, 5 (5), pp.273 - 283. <a target=\"_blank\" href=\"https://dx.doi.org/10.4049/immunohorizons.2000095\">⟨10.4049/immunohorizons.2000095⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03429701v1\">⟨hal-03429701⟩</a>", "title_s":["Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling"], "authFullName_s":["Claire Mackowiak","Tiffany Marchiol","Hana Cipcic Paljetak","Louis Fauconnier","Jennifer Palomo","Thomas Secher","Corinne Panek","Delphine Sedda","Florence Savigny","François Erard","Alessandra Bragonzi","Francois Huaux","Tobias Stoeger","Herbert B Schiller","Jean-Claude Sirard","M Le Bert","Isabelle Couillin","Valérie Quesniaux","Dieudonnée Togbe","Bernhard Ryffel"], "halId_s":"hal-03429701", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"American Journal of Respiratory Cell and Molecular Biology, 2021, 65 (4), pp.378-389. <a target=\"_blank\" href=\"https://dx.doi.org/10.1165/rcmb.2021-0125OC\">⟨10.1165/rcmb.2021-0125OC⟩</a>", "citationFull_s":"Raquel López-Gálvez, Isabelle Fleurot, Pablo Chamero, Sascha Trapp, Olivier Michel, et al.. Airway administration of flagellin regulates the inflammatory response to Pseudomonas aeruginosa. American Journal of Respiratory Cell and Molecular Biology, 2021, 65 (4), pp.378-389. <a target=\"_blank\" href=\"https://dx.doi.org/10.1165/rcmb.2021-0125OC\">⟨10.1165/rcmb.2021-0125OC⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-03258174v1\">⟨hal-03258174⟩</a>", "title_s":["Airway administration of flagellin regulates the inflammatory response to Pseudomonas aeruginosa"], "authFullName_s":["Raquel López-Gálvez","Isabelle Fleurot","Pablo Chamero","Sascha Trapp","Olivier Michel","Claire Chevaleyre","Céline Barc","Mickael Riou","Christelle Rossignol","Antoine Guillon","Mustapha Si-Tahar","Tobias May","Pascal Barbry","Andrea Bähr","Nikolai Klymiuk","Jean Claude Sirard","Ignacio Caballero"], "halId_s":"hal-03258174", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"ACS Infectious Diseases, 2021, Online ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1021/acsinfecdis.1c00176\">⟨10.1021/acsinfecdis.1c00176⟩</a>", "citationFull_s":"Fiordiligie Casilag, Laura Matarazzo, Sebastian Franck, Martin Figeac, Robin Michelet, et al.. The Biosynthetic Monophosphoryl Lipid A Enhances the Therapeutic Outcome of Antibiotic Therapy in Pneumococcal Pneumonia.. ACS Infectious Diseases, 2021, Online ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1021/acsinfecdis.1c00176\">⟨10.1021/acsinfecdis.1c00176⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-03288018v1\">⟨inserm-03288018⟩</a>", "title_s":["The Biosynthetic Monophosphoryl Lipid A Enhances the Therapeutic Outcome of Antibiotic Therapy in Pneumococcal Pneumonia."], "authFullName_s":["Fiordiligie Casilag","Laura Matarazzo","Sebastian Franck","Martin Figeac","Robin Michelet","Charlotte Kloft","Christophe Carnoy","Jean-Claude Sirard"], "halId_s":"inserm-03288018", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"ImmunoHorizons , 2021, 5 (5), pp.273-283. <a target=\"_blank\" href=\"https://dx.doi.org/10.4049/immunohorizons.2000095\">⟨10.4049/immunohorizons.2000095⟩</a>", "citationFull_s":"Claire Mackowiak, Tiffany Marchiol, Hana Cipcic Paljetak, Louis Fauconnier, Jennifer Palomo, et al.. Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling. ImmunoHorizons , 2021, 5 (5), pp.273-283. <a target=\"_blank\" href=\"https://dx.doi.org/10.4049/immunohorizons.2000095\">⟨10.4049/immunohorizons.2000095⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-03258180v1\">⟨hal-03258180⟩</a>", "title_s":["Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling"], "authFullName_s":["Claire Mackowiak","Tiffany Marchiol","Hana Cipcic Paljetak","Louis Fauconnier","Jennifer Palomo","Thomas Secher","Corinne Panek","Delphine Sedda","Florence Savigny","François Erard","Alessandra Bragonzi","Francois Huaux","Tobias Stoeger","Herbert B. Schiller","Jean Claude Sirard","Marc Le Bert","Isabelle Couillin","Valérie Quesniaux","Dieudonnée Togbe","Bernhard Ryffel"], "halId_s":"hal-03258180", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"Pharmaceutics, 2021, 13 (5), pp.601. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/pharmaceutics13050601\">⟨10.3390/pharmaceutics13050601⟩</a>", "citationFull_s":"Robin Michelet, Moreno Ursino, Sandrine Boulet, Sebastian Franck, Fiordiligie Casilag, et al.. The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia. Pharmaceutics, 2021, 13 (5), pp.601. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/pharmaceutics13050601\">⟨10.3390/pharmaceutics13050601⟩</a>. <a target=\"_blank\" href=\"https://hal.sorbonne-universite.fr/hal-03215662v1\">⟨hal-03215662⟩</a>", "title_s":["The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia"], "authFullName_s":["Robin Michelet","Moreno Ursino","Sandrine Boulet","Sebastian Franck","Fiordiligie Casilag","Mara Baldry","Jens Rolff","Madelé van Dyk","Sebastian Wicha","Jean-Claude Sirard","Emmanuelle Comets","Sarah Zohar","Charlotte Kloft"], "halId_s":"hal-03215662", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"PLoS Pathogens, 2021, 17 (4), <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.ppat.1009491\">⟨10.1371/journal.ppat.1009491⟩</a>", "citationFull_s":"Wanhai Qin, Xanthe Brands, Cornelis Van’t Veer, Alex F. de Vos, Jean Claude Sirard, et al.. Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection. PLoS Pathogens, 2021, 17 (4), <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.ppat.1009491\">⟨10.1371/journal.ppat.1009491⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-03258188v1\">⟨hal-03258188⟩</a>", "title_s":["Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection"], "authFullName_s":["Wanhai Qin","Xanthe Brands","Cornelis Van’t Veer","Alex F. de Vos","Jean Claude Sirard","Joris J. T. H. Roelofs","Brendon P. Scicluna","Tom van Der Poll"], "halId_s":"hal-03258188", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"Pharmaceutics, 2021, 13 (4), pp.1-12. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/pharmaceutics13040469\">⟨10.3390/pharmaceutics13040469⟩</a>", "citationFull_s":"Sebastian Franck, Robin Michelet, Fiordiligie Casilag, Jean Claude Sirard, Sebastian G. Wicha, et al.. A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice. Pharmaceutics, 2021, 13 (4), pp.1-12. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/pharmaceutics13040469\">⟨10.3390/pharmaceutics13040469⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-03258185v1\">⟨hal-03258185⟩</a>", "title_s":["A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice"], "authFullName_s":["Sebastian Franck","Robin Michelet","Fiordiligie Casilag","Jean Claude Sirard","Sebastian G. Wicha","Charlotte Kloft"], "halId_s":"hal-03258185", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"PLoS ONE, 2021, 16 (3), <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.pone.0236216\">⟨10.1371/journal.pone.0236216⟩</a>", "citationFull_s":"Magdiel Pérez-Cruz, Bachirou Koné, Rémi Porte, Christophe Carnoy, Julien Tabareau, et al.. The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice. PLoS ONE, 2021, 16 (3), <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.pone.0236216\">⟨10.1371/journal.pone.0236216⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-03258191v1\">⟨hal-03258191⟩</a>", "title_s":["The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice"], "authFullName_s":["Magdiel Pérez-Cruz","Bachirou Koné","Rémi Porte","Christophe Carnoy","Julien Tabareau","Pierre Gosset","François Trottein","Jean Claude Sirard","Muriel Pichavant","Philippe Gosset"], "halId_s":"hal-03258191", "docType_s":"ART", "producedDateY_i":2021 },{ "citationRef_s":"Mucosal Immunology, 2021, 14 (3), pp.594-604. <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/s41385-021-00377-8\">⟨10.1038/s41385-021-00377-8⟩</a>", "citationFull_s":"I. 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Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1789 (5), pp.386-94. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bbagrm.2009.03.001\">⟨10.1016/j.bbagrm.2009.03.001⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00385296v1\">⟨inserm-00385296⟩</a>", "title_s":["Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics."], "authFullName_s":["Jean-Claude Sirard","Arnaud Didierlaurent","Delphine Cayet","Frédéric Sierro","Martin Rumbo"], "halId_s":"inserm-00385296", "docType_s":"ART", "producedDateY_i":2009 },{ "citationRef_s":"Journal of Immunology, 2008, 181 (3), pp.2036-2043. <a target=\"_blank\" href=\"https://dx.doi.org/10.4049/jimmunol.181.3.2036\">⟨10.4049/jimmunol.181.3.2036⟩</a>", "citationFull_s":"Clément Nempont, Delphine Cayet, Martin Rumbo, Coralie Bompard, Vincent Villeret, et al.. Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity.. 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Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.. Journal of Experimental Medicine, 2008, 205 (2), pp.323-9. <a target=\"_blank\" href=\"https://dx.doi.org/10.1084/jem.20070891\">⟨10.1084/jem.20070891⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00227540v1\">⟨inserm-00227540⟩</a>", "title_s":["Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection."], "authFullName_s":["Arnaud Didierlaurent","John Goulding","Seema Patel","Robert Snelgrove","Lionel Low","Magali Bebien","Toby Lawrence","Leonie S. van Rijt","Bart N. 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PLoS Pathogens, 2007, 3 (12), pp.e152. <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.ppat.0030152\">⟨10.1371/journal.ppat.0030152⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00223906v1\">⟨inserm-00223906⟩</a>", "title_s":["Nod-like receptors: cytosolic watchdogs for immunity against pathogens."], "authFullName_s":["Jean-Claude Sirard","Cécile Vignal","Rodrigue Dessein","Mathias Chamaillard"], "halId_s":"inserm-00223906", "docType_s":"ART", "producedDateY_i":2007 },{ "citationRef_s":"Microbiology, 2007, 153 (Pt 4), pp.1059-69. <a target=\"_blank\" href=\"https://dx.doi.org/10.1099/mic.0.2006/000331-0\">⟨10.1099/mic.0.2006/000331-0⟩</a>", "citationFull_s":"Aizhen Guo, Melissa A. Lasaro, Jean-Claude Sirard, Jean-Pierre Kraehenbuhl, Dieter M. Schifferli. Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells.. Microbiology, 2007, 153 (Pt 4), pp.1059-69. <a target=\"_blank\" href=\"https://dx.doi.org/10.1099/mic.0.2006/000331-0\">⟨10.1099/mic.0.2006/000331-0⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00177727v1\">⟨inserm-00177727⟩</a>", "title_s":["Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells."], "authFullName_s":["Aizhen Guo","Melissa A. Lasaro","Jean-Claude Sirard","Jean-Pierre Kraehenbuhl","Dieter M. Schifferli"], "halId_s":"inserm-00177727", "docType_s":"ART", "producedDateY_i":2007 },{ "citationRef_s":"PLoS ONE, 2007, 2 (3), pp.e313. <a target=\"_blank\" href=\"https://dx.doi.org/10.1371/journal.pone.0000313\">⟨10.1371/journal.pone.0000313⟩</a>", "citationFull_s":"Benoit Foligne, Georgia Zoumpopoulou, Joelle Dewulf, Amena Ben Younes, Fabrice Chareyre, et al.. A key role of dendritic cells in probiotic functionality.. 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Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.. FEBS Letters, 2006, 580 (12), pp.2976-84. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.febslet.2006.04.036\">⟨10.1016/j.febslet.2006.04.036⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00071278v1\">⟨inserm-00071278⟩</a>", "title_s":["Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5."], "authFullName_s":["Martin Rumbo","Clément Nempont","Jean-Pierre Kraehenbuhl","Jean-Claude Sirard"], "halId_s":"inserm-00071278", "docType_s":"ART", "producedDateY_i":2006 },{ "citationRef_s":"European Journal of Immunology, 2006, 36, pp.260-3. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/eji.200535777\">⟨10.1002/eji.200535777⟩</a>", "citationFull_s":"Jean-Claude Sirard, Mariela Bayardo, Arnaud Didierlaurent. Pathogen-specific TLR signaling in mucosa: mutual contribution of microbial TLR agonists and virulence factors.. European Journal of Immunology, 2006, 36, pp.260-3. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/eji.200535777\">⟨10.1002/eji.200535777⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00000042v1\">⟨inserm-00000042⟩</a>", "title_s":["Pathogen-specific TLR signaling in mucosa: mutual contribution of microbial TLR agonists and virulence factors."], "authFullName_s":["Jean-Claude Sirard","Mariela Bayardo","Arnaud Didierlaurent"], "halId_s":"inserm-00000042", "docType_s":"ART", "producedDateY_i":2006 },{ "citationRef_s":"Molecular and Cellular Biology, 2006, 26, pp.735-42. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/MCB.26.3.735-742.2006\">⟨10.1128/MCB.26.3.735-742.2006⟩</a>", "citationFull_s":"Arnaud Didierlaurent, Brian Brissoni, Dominique Velin, Natalia Aebi, Aubry Tardivel, et al.. Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide.. Molecular and Cellular Biology, 2006, 26, pp.735-42. <a target=\"_blank\" href=\"https://dx.doi.org/10.1128/MCB.26.3.735-742.2006\">⟨10.1128/MCB.26.3.735-742.2006⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00000043v1\">⟨inserm-00000043⟩</a>", "title_s":["Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide."], "authFullName_s":["Arnaud Didierlaurent","Brian Brissoni","Dominique Velin","Natalia Aebi","Aubry Tardivel","Edgar Käslin","Jean Claude Sirard","Georgi S. Angelov","Jürg Tschopp","Kimberly Burns"], "halId_s":"inserm-00000043", "docType_s":"ART", "producedDateY_i":2006 },{ "citationRef_s":"Immunity, 2006, 24, pp.191-201. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.immuni.2006.01.005\">⟨10.1016/j.immuni.2006.01.005⟩</a>", "citationFull_s":"Marie Le Borgne, Nathalie Etchart, Anne Goubier, Sergio A. Lira, Jean Claude Sirard, et al.. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.. Immunity, 2006, 24, pp.191-201. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.immuni.2006.01.005\">⟨10.1016/j.immuni.2006.01.005⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-00000041v1\">⟨inserm-00000041⟩</a>", "title_s":["Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo."], "authFullName_s":["Marie Le Borgne","Nathalie Etchart","Anne Goubier","Sergio A. 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Jean-Claude Sirard

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