Alessandro Furlan
Publications
Alessandro Furlan, Mélanie Arcicasa, Samuel Meignan
Interdisciplinary approaches to investigate the tumor microenvironment
Mifobio 2023 Functional Microscopy for Biology, Nov 2023, Hyères, France
Alessandro Furlan, Lisa Terrassoux, Joanne Balsamelli, Samuel Meignan
A tumor-on-chip as a DIPG model mimicking tumor microenvironment
Functional investigation of multicellular systems with light probes, Jun 2023, Paris, France
Lisa Terrassoux, Hugo Claux, Salimata Bacari, Samuel Meignan, Alessandro Furlan
A Bloody Conspiracy— Blood Vessels and Immune Cells in the Tumor Microenvironment
Cancers, 2022, 14 (19), pp.4581. ⟨10.3390/cancers14194581⟩
Alan Vandenberghe, Marc Lefranc, Alessandro Furlan
An Overview of the Circadian Clock in the Frame of Chronotherapy: From Bench to Bedside
Pharmaceutics, 2022, 14 (7), pp.1424. ⟨10.3390/pharmaceutics14071424⟩
Quentin Bailleul, Pauline Navarin, Mélanie Arcicasa, Christine Bal-Mahieu, Angel Montero Carcaboso, Xuefen Le Bourhis, Alessandro Furlan, Samuel Meignan, Pierre Leblond
Evofosfamide Is Effective against Pediatric Aggressive Glioma Cell Lines in Hypoxic Conditions and Potentiates the Effect of Cytotoxic Chemotherapy and Ionizing Radiations
Cancers, 2021, 13 (8), pp.1804. ⟨10.3390/cancers13081804⟩
Andria Rakotomalala, Alexandre Escande, Alessandro Furlan, Samuel Meignan, Eric Lartigau
Hypoxia in Solid Tumors: How Low Oxygenation Impacts the “Six Rs” of Radiotherapy
Frontiers in Endocrinology, 2021, 12, pp.742215. ⟨10.3389/fendo.2021.742215⟩
Leslie Duplaquet, Catherine Leroy, Audrey Vinchent, Sonia Paget, Jonathan Lefebvre, Fabien Vanden Abeele, Steve S. Lancel, Florence Giffard, Réjane Paumelle, Gabriel Bidaux, Laurent Heliot, Laurent Poulain, Alessandro Furlan, David Tulasne
Control of cell death/survival balance by the MET dependence receptor
eLife, 2020, 9, pp.e50041. ⟨10.7554/eLife.50041⟩
Emmanuel Bresso, Alessandro Furlan, Philippe Noel, Vincent Leroux, Flavio Maina, Rosanna Dono, Bernard Maigret
Large-Scale Virtual Screening Against the MET Kinase Domain Identifies a New Putative Inhibitor Type
Molecules, 2020, 25 (4), pp.938. ⟨10.3390/molecules25040938⟩
Alessandro Furlan, Mariano Gonzalez-Pisfil, Aymeric Leray, Dorian Champelovier, Mélanie Henry, Corentin Le Nézet, Oliver Bensaude, Marc Lefranc, Thorsten Wohland, Bernard Vandenbunder, Gabriel Bidaux, Laurent Héliot
HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb
Biophysical Journal, 2019, 117 (9), pp.1615-1625. ⟨10.1016/j.bpj.2019.09.019⟩
Alessandro Furlan, Marine Jacquier, Aurore Woller, Laurent Héliot, Hélène Duez, Bart Staels, Marc Lefranc
Mathematical models converge on PGC1α as the key metabolic integrator of SIRT1 and AMPK regulation of the circadian clock
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (27), pp.13171-13172. ⟨10.1073/pnas.1907751116⟩
Nouveaux outils interdisciplinaires pour l’étude des réseaux de signalisation cellulaire et de transcription
Sciences du Vivant [q-bio]. Lille University, 2019
Alessandro Furlan, Florence Agbazahou, Mélanie Henry, Mariano Gonzalez-Pisfil, Corentin Le Nézet, Dorian Champelovier, Marie Fournier, Bernard Vandenbunder, Gabriel Bidaux, Laurent Héliot
P-TEFb et Brd4
Médecine/Sciences, 2018, 34 (8-9), pp.685-692. ⟨10.1051/medsci/20183408015⟩
Gabriel Bidaux, Corentin Le Nézet, Mariano Gonzalez Pisfil, Mélanie Henry, Alessandro Furlan, Oliver Bensaude, Bernard Vandenbunder, Laurent Héliot
FRET Image Correlation Spectroscopy Reveals RNAPII-Independent P-TEFb Recruitment on Chromatin
Biophysical Journal, 2018, 114 (3), pp.522-533. ⟨10.1016/j.bpj.2017.11.3783⟩
Alessandro Furlan, Chantal Vercamer, Laurent Héliot, Nicolas Wernert, Xavier Desbiens, Albin Pourtier
Ets-1 drives breast cancer cell angiogenic potential and interactions between breast cancer and endothelial cells
International Journal of Oncology, 2018, 54 (1), pp.29-40. ⟨10.3892/ijo.2018.4605⟩
Alexis Cortot, Zoulika Kherrouche, Clotilde Descarpentries, Marie Wislez, Simon Baldacci, Alessandro Furlan, David Tulasne
Exon 14 Deleted MET Receptor as a New Biomarker and Target in Cancers
JNCI: Journal of the National Cancer Institute, 2017, 109 (5), pp.djw262. ⟨10.1093/jnci/djw262⟩
Jieshuang Jia, Alessandro Furlan, Sara Gonzalez-Hilarion, Catherine Leroy, Dieter Gruenert, David Tulasne, Fabrice Lejeune
Caspases shutdown nonsense-mediated mRNA decay during apoptosis
Cell Death and Differentiation, 2015, 22, pp.1754 - 1763. ⟨10.1038/cdd.2015.18⟩
Alessandro Furlan, Albin Pourtier
Ets-1 activation, when tumors crosstalk with their microenvironment.
Cancer Cell & Microenvironment, 2015, ⟨10.14800/ccm.494⟩
Alessandro Furlan, Chantal Vercamer, Fatima Bouali, Isabelle Damour, Anne Chotteau-Lelievre, Nicolas Wernert, Xavier Desbiens, Albin Pourtier
Ets-1 controls breast cancer cell balance between invasion and growth
International Journal of Cancer, 2014, 135 (10), pp.2317-2328. ⟨10.1002/ijc.28881⟩
Rémi Montagne, Alessandro Furlan, Zoulika Kherrouche, David Tulasne
Le récepteur Met fête ses 30 ans: de la découverte d’un oncogène au développement de thérapies ciblées
Médecine/Sciences, 2014, 30 (10), pp.864-873. ⟨10.1051/medsci/20143010013⟩
Alessandro Furlan, David Tulasne
How does met regulate the survival/apoptosis balance?
Hepatology, 2014, 60 (3), pp.1108-1109. ⟨10.1002/hep.26969⟩
Alessandro Furlan, Fabienne Lamballe, Venturina Stagni, Azeemudeen Hussain, Sylvie Richelme, Andrea Prodosmo, Anice Moumen, Christine Brun, Ivan del Barco Barrantes, J Simon C Arthur, Anthony J Koleske, Angel R Nebreda, Daniela Barilà, Flavio Maina
Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver.
Journal of Hepatology, 2012, 57 (6), pp.1292-8. ⟨10.1016/j.jhep.2012.07.044⟩
Alessandro Furlan, Benjamin Roux, Fabienne Lamballe, Filippo Conti, Nathalie Issaly, Fabrice Daian, Jean-François Guillemot, Sylvie Richelme, Magali Contensin, Joan Bosch, Daniele Passarella, Oreste Piccolo, Rosanna Dono, Flavio Maina
Combined Drug Action of 2-Phenylimidazo[2,1-b]Benzothiazole Derivatives on Cancer Cells According to Their Oncogenic Molecular Signatures
PLoS ONE, 2012, 7 (10), pp.e46738. ⟨10.1371/journal.pone.0046738⟩
Francesco Colombo, Cristina Tintori, Alessandro Furlan, Stella Borrelli, Michael S Christodoulou, Rosanna Dono, Flavio Maina, Maurizio Botta, Mercedes Amat, Joan Bosch, Daniele Passarella
Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.
Bioorganic and Medicinal Chemistry Letters, 2012, 22 (14), pp.4693-6. ⟨10.1016/j.bmcl.2012.05.078⟩
Francesco Colombo, Cristina Tintori, Alessandro Furlan, Stella Borrelli, Michael Christodoulou, Rosanna Dono, Flavio Maina, Maurizio Botta, Mercedes Amat, Joan Bosch, Daniele Passarella
‘Click’ synthesis of a triazole-based inhibitor of Met functions in cancer cells
Bioorganic and Medicinal Chemistry Letters, 2012, 22 (14), pp.4693-4696. ⟨10.1016/j.bmcl.2012.05.078⟩
Alessandro Furlan, Francesco Colombo, Andrea Kover, Nathalie Issaly, Cristina Tintori, Lucilla Angeli, Vincent Leroux, Sébastien Letard, Mercedes Amat, Yasmine Asses, Bernard Maigret, Patrice Dubreuil, Maurizio Botta, Rosanna Dono, Joan Bosch, Oreste Piccolo, Daniele Passarella, Flavio Maina
Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling
European Journal of Medicinal Chemistry, 2012, 47, pp.239-254. ⟨10.1016/j.ejmech.2011.10.051⟩
Alessandro Furlan, Benjamin Roux, Fabienne Lamballe, Filippo Conti, Nathalie Issaly, Fabrice Daian, Jean-François Guillemot, Sylvie Richelme, Magali Contensin, Joan Bosch, Daniele Passarella, Oreste Piccolo, Rosanna Dono, Flavio Maina
Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures
PLoS ONE, 2012, 7 (10), pp.e46738. ⟨10.1371/journal.pone.0046738⟩
Flavio Maina, Alessandro Furlan, Filippo Conti, Azeemudeen Hussain, Sylvie Richelme, Venturina Stagni, Daniela Barilà, Andrea Prodosmo, Annarita Destro, Massimo Roncalli
Abl interconnects oncogenic Met and p53 core pathways in cancer cells
Cell Death and Differentiation, 2011, ⟨10.1038/cdd.2011.23⟩
Alessandro Furlan, Chantal Vercamer, Xavier Desbiens, Albin Pourtier
Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment
Journal of Cellular Physiology, 2008, 215 (3), pp.782-793. ⟨10.1002/jcp.21360⟩
Sylvain Julien, Eric Adriaenssens, Katherin Ottenberg, Alessandro Furlan, Gilles Courtand, Anne-Sophie Vercouter Edouart, Franz-Georg Hanisch, Philippe Delannoy, Xuefen Le Bourhis
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.
Glycobiology, 2006, 16, pp.54-64
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