Publications

{ "response":{"numFound":45,"start":0,"numFoundExact":true,"docs":[ { "citationRef_s":"France, Patent n° : EP23306103. 2023", "citationFull_s":"Xavier Thuru, Frédérique Klupsch, Christian Bailly, Régis Millet, Raphael Le Biannic, et al.. NOVEL PYRAZOLE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS. France, Patent n° : EP23306103. 2023. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-04542066\">⟨inserm-04542066⟩</a>", "title_s":["NOVEL PYRAZOLE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS"], "authFullName_s":["Xavier Thuru", "Frédérique Klupsch", "Christian Bailly", "Régis Millet", "Raphael Le Biannic", "Bruno Quesnel"], "halId_s":"inserm-04542066", "docType_s":"PATENT", "producedDateY_i":2023}, { "citationRef_s":"Molecules, 2023, 28 (8), pp.3491. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/molecules28083491\">⟨10.3390/molecules28083491⟩</a>", "citationFull_s":"Romain Regnault, Frédérique Klupsch, Hassiba El-Bouazzati, Romain Magnez, Raphaël Le Biannic, et al.. Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties. Molecules, 2023, 28 (8), pp.3491. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/molecules28083491\">⟨10.3390/molecules28083491⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-04139041\">⟨hal-04139041⟩</a>", "title_s":["Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties"], "authFullName_s":["Romain Regnault", "Frédérique Klupsch", "Hassiba El-Bouazzati", "Romain Magnez", "Raphaël Le Biannic", "Natascha Leleu-Chavain", "Hania Ahouari", "Herve Vezin", "Régis Millet", "Jean-François Goossens", "Xavier Thuru", "Christian Bailly"], "halId_s":"hal-04139041", "docType_s":"ART", "producedDateY_i":2023}, { "citationRef_s":"Biochemical Pharmacology, 2023, 209, pp.115445. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bcp.2023.115445\">⟨10.1016/j.bcp.2023.115445⟩</a>", "citationFull_s":"Christian Bailly, Xavier Thuru, Laurence Goossens, Jean-François Goossens. Soluble TIM-3 as a biomarker of progression and therapeutic response in cancers and other of human diseases. Biochemical Pharmacology, 2023, 209, pp.115445. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bcp.2023.115445\">⟨10.1016/j.bcp.2023.115445⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03990928\">⟨hal-03990928⟩</a>", "title_s":["Soluble TIM-3 as a biomarker of progression and therapeutic response in cancers and other of human diseases"], "authFullName_s":["Christian Bailly", "Xavier Thuru", "Laurence Goossens", "Jean-François Goossens"], "halId_s":"hal-03990928", "docType_s":"ART", "producedDateY_i":2023}, { "citationRef_s":"Biomedicine hub = Biomed Hub, 2023, 8 (1), pp.1-9. <a target=\"_blank\" href=\"https://dx.doi.org/10.1159/000528499\">⟨10.1159/000528499⟩</a>", "citationFull_s":"Xavier Thuru, Romain Magnez, Gérard Vergoten, Christian Bailly. A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition. Biomedicine hub = Biomed Hub, 2023, 8 (1), pp.1-9. <a target=\"_blank\" href=\"https://dx.doi.org/10.1159/000528499\">⟨10.1159/000528499⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-03990317\">⟨inserm-03990317⟩</a>", "title_s":["A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition"], "authFullName_s":["Xavier Thuru", "Romain Magnez", "Gérard Vergoten", "Christian Bailly"], "halId_s":"inserm-03990317", "docType_s":"ART", "producedDateY_i":2023}, { "citationRef_s":"Cancers, 2022, 14 (14), pp.3368. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers14143368\">⟨10.3390/cancers14143368⟩</a>", "citationFull_s":"Xavier Thuru, Romain Magnez, Hassiba El-Bouazzati, Gérard Vergoten, Bruno Quesnel, et al.. Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors. Cancers, 2022, 14 (14), pp.3368. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers14143368\">⟨10.3390/cancers14143368⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03857329\">⟨hal-03857329⟩</a>", "title_s":["Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors"], "authFullName_s":["Xavier Thuru", "Romain Magnez", "Hassiba El-Bouazzati", "Gérard Vergoten", "Bruno Quesnel", "Christian Bailly"], "halId_s":"hal-03857329", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"European Journal of Medicinal Chemistry, 2022, 236, pp.114343. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.ejmech.2022.114343\">⟨10.1016/j.ejmech.2022.114343⟩</a>", "citationFull_s":"Raphaël Le Biannic, Romain Magnez, Frédérique Klupsch, Natascha Leleu-Chavain, Bryan Thiroux, et al.. Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction. European Journal of Medicinal Chemistry, 2022, 236, pp.114343. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.ejmech.2022.114343\">⟨10.1016/j.ejmech.2022.114343⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03641793\">⟨hal-03641793⟩</a>", "title_s":["Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction"], "authFullName_s":["Raphaël Le Biannic", "Romain Magnez", "Frédérique Klupsch", "Natascha Leleu-Chavain", "Bryan Thiroux", "Morgane Tardy", "Hassiba El Bouazzati", "Xavier Dezitter", "Nicolas Renault", "Gérard Vergoten", "Christian Bailly", "Bruno Quesnel", "Xavier Thuru", "Régis Millet"], "halId_s":"hal-03641793", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"Molecules, 2022, Molecules, 27 (10), pp.3316. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/molecules27103316\">⟨10.3390/molecules27103316⟩</a>", "citationFull_s":"Natascha Leleu, Romain Regnault, Hania Ahouari, Raphael Le Biannic, Mostafa Kouach, et al.. Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents. Molecules, 2022, Molecules, 27 (10), pp.3316. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/molecules27103316\">⟨10.3390/molecules27103316⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03714935\">⟨hal-03714935⟩</a>", "title_s":["Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents"], "authFullName_s":["Natascha Leleu", "Romain Regnault", "Hania Ahouari", "Raphael Le Biannic", "Mostafa Kouach", "Frederique Klupsch", "Romain Magnez", "Herve Vezin", "Xavier Thuru", "Christian Bailly", "Jean-Francois Goossens", "Régis Millet"], "halId_s":"hal-03714935", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"SEPARATION SCIENCE PLUS, 2022, SEPARATION SCIENCE PLUS, <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/sscp.202200031\">⟨10.1002/sscp.202200031⟩</a>", "citationFull_s":"Romain Regnault, Mostafa Kouach, Laurence Goossens, Xavier Thuru, Christian Bailly, et al.. Mono- and bis-edaravone adducts formed in the presence of vanillin in an aqueous solution. SEPARATION SCIENCE PLUS, 2022, SEPARATION SCIENCE PLUS, <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/sscp.202200031\">⟨10.1002/sscp.202200031⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-04201660\">⟨hal-04201660⟩</a>", "title_s":["Mono- and bis-edaravone adducts formed in the presence of vanillin in an aqueous solution"], "authFullName_s":["Romain Regnault", "Mostafa Kouach", "Laurence Goossens", "Xavier Thuru", "Christian Bailly", "Jean-Francois Goossens"], "halId_s":"hal-04201660", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"Cells, 2022, 11 (6), pp.1018. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cells11061018\">⟨10.3390/cells11061018⟩</a>", "citationFull_s":"Antoine Marchand, Alessia Sarchione, Panagiotis Athanasopoulos, Hélène Bauderlique-Le Roy, Liesel Goveas, et al.. A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively. Cells, 2022, 11 (6), pp.1018. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cells11061018\">⟨10.3390/cells11061018⟩</a>. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-03625821\">⟨inserm-03625821⟩</a>", "title_s":["A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively"], "authFullName_s":["Antoine Marchand", "Alessia Sarchione", "Panagiotis Athanasopoulos", "Hélène Bauderlique-Le Roy", "Liesel Goveas", "Romain Magnez", "Matthieu Drouyer", "Marco Emanuele", "Franz Ho", "Maxime Liberelle", "Patricia Melnyk", "Nicolas Lebègue", "Xavier Thuru", "R. Jeremy Nichols", "Elisa Greggio", "Arjan Kortholt", "Thierry Galli", "Marie-Christine Chartier-Harlin", "Jean-Marc Taymans"], "halId_s":"inserm-03625821", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"International Journal of Molecular Sciences, 2022, 23 (14), pp.7672. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/ijms23147672\">⟨10.3390/ijms23147672⟩</a>", "citationFull_s":"Romain Magnez, Christian Bailly, Xavier Thuru. Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases. International Journal of Molecular Sciences, 2022, 23 (14), pp.7672. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/ijms23147672\">⟨10.3390/ijms23147672⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03857337\">⟨hal-03857337⟩</a>", "title_s":["Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases"], "authFullName_s":["Romain Magnez", "Christian Bailly", "Xavier Thuru"], "halId_s":"hal-03857337", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"Science Immunology, 2022, 7 (78), pp.ade5686. <a target=\"_blank\" href=\"https://dx.doi.org/10.1126/sciimmunol.ade5686\">⟨10.1126/sciimmunol.ade5686⟩</a>", "citationFull_s":"Silvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, Paul Fyfe, Malo Leprohon, et al.. IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. Science Immunology, 2022, 7 (78), pp.ade5686. <a target=\"_blank\" href=\"https://dx.doi.org/10.1126/sciimmunol.ade5686\">⟨10.1126/sciimmunol.ade5686⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04276595\">⟨hal-04276595⟩</a>", "title_s":["IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein"], "authFullName_s":["Silvia Gaggero", "Jonathan Martinez-Fabregas", "Adeline Cozzani", "Paul Fyfe", "Malo Leprohon", "Jie Yang", "F. Emil Thomasen", "Hauke Winkelmann", "Romain Magnez", "Alberto Conti", "Stephan Wilmes", "Elizabeth Pohler", "Manuel van Gijsel Bonnello", "Xavier Thuru", "Bruno Quesnel", "Fabrice Soncin", "Jacob Piehler", "Kresten Lindorff-Larsen", "Rahul Roychoudhuri", "Ignacio Moraga", "Suman Mitra"], "halId_s":"hal-04276595", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"Movement Disorders, 2022, <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/mds.29124\">⟨10.1002/mds.29124⟩</a>", "citationFull_s":"Ilda Coku, Eugénie Mutez, Sabiha Eddarkaoui, Sébastien Carrier, Antoine Marchand, et al.. Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.. Movement Disorders, 2022, <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/mds.29124\">⟨10.1002/mds.29124⟩</a>. <a target=\"_blank\" href=\"https://u-picardie.hal.science/hal-03703786\">⟨hal-03703786⟩</a>", "title_s":["Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease."], "authFullName_s":["Ilda Coku", "Eugénie Mutez", "Sabiha Eddarkaoui", "Sébastien Carrier", "Antoine Marchand", "Claire Deldycke", "Liesel Goveas", "Guillaume Baille", "Mélissa Tir", "Romain Magnez", "Xavier Thuru", "Gaëlle Vermeersch", "Wim Vandenberghe", "Luc Buée", "Luc Defebvre", "Bernard Sablonnière", "Marie-Christine Chartier-Harlin", "Jean-Marc Taymans", "Vincent Huin"], "halId_s":"hal-03703786", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"Journal of Cellular Biochemistry, 2022, 123 (3), pp.543-556. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/jcb.30198\">⟨10.1002/jcb.30198⟩</a>", "citationFull_s":"Yasmine Touil, Céline Latreche‐carton, Hassiba El Bouazzati, Anne‐lucie Nugues, Nathalie Jouy, et al.. p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics. Journal of Cellular Biochemistry, 2022, 123 (3), pp.543-556. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/jcb.30198\">⟨10.1002/jcb.30198⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03641788\">⟨hal-03641788⟩</a>", "title_s":["p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics"], "authFullName_s":["Yasmine Touil", "Céline Latreche‐carton", "Hassiba El Bouazzati", "Anne‐lucie Nugues", "Nathalie Jouy", "Xavier Thuru", "William Laine", "Frederic Lepretre", "Martin Figeac", "Meryem Tardivel", "Jérôme Kluza", "Thierry Idziorek", "Bruno Quesnel"], "halId_s":"hal-03641788", "docType_s":"ART", "producedDateY_i":2022}, { "citationRef_s":"European Journal of Medicinal Chemistry, 2021, 226, pp.113835. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.ejmech.2021.113835\">⟨10.1016/j.ejmech.2021.113835⟩</a>", "citationFull_s":"Manon Sturbaut, Fabrice Bailly, Mathilde Coevoet, Pasquale Sileo, Martine Pugniere, et al.. Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors. European Journal of Medicinal Chemistry, 2021, 226, pp.113835. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.ejmech.2021.113835\">⟨10.1016/j.ejmech.2021.113835⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03429462\">⟨hal-03429462⟩</a>", "title_s":["Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors"], "authFullName_s":["Manon Sturbaut", "Fabrice Bailly", "Mathilde Coevoet", "Pasquale Sileo", "Martine Pugniere", "Maxime Liberelle", "Romain Magnez", "Xavier Thuru", "Marie-Christine Chartier-Harlin", "Patricia Melnyk", "Muriel Gelin", "Frédéric Allemand", "Jean-François Guichou", "Philippe Cotelle"], "halId_s":"hal-03429462", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"Cancers, 2021, 13 (24), pp.6365. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13246365\">⟨10.3390/cancers13246365⟩</a>", "citationFull_s":"Christian Bailly, Xavier Thuru, Bruno Quesnel. Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?. Cancers, 2021, 13 (24), pp.6365. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13246365\">⟨10.3390/cancers13246365⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03641796\">⟨hal-03641796⟩</a>", "title_s":["Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?"], "authFullName_s":["Christian Bailly", "Xavier Thuru", "Bruno Quesnel"], "halId_s":"hal-03641796", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"Frontiers in Cell and Developmental Biology, 2021, 9, pp.740550. <a target=\"_blank\" href=\"https://dx.doi.org/10.3389/fcell.2021.740550\">⟨10.3389/fcell.2021.740550⟩</a>", "citationFull_s":"Thomas Rico, Melissa Gilles, Alban Chauderlier, Thomas Comptdaer, Romain Magnez, et al.. Tau Stabilizes Chromatin Compaction. Frontiers in Cell and Developmental Biology, 2021, 9, pp.740550. <a target=\"_blank\" href=\"https://dx.doi.org/10.3389/fcell.2021.740550\">⟨10.3389/fcell.2021.740550⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03429442\">⟨hal-03429442⟩</a>", "title_s":["Tau Stabilizes Chromatin Compaction"], "authFullName_s":["Thomas Rico", "Melissa Gilles", "Alban Chauderlier", "Thomas Comptdaer", "Romain Magnez", "Maggy Chwastyniak", "Herve Drobecq", "Florence Pinet", "Xavier Thuru", "Luc Buée", "Marie-Christine Galas", "Bruno Lefebvre"], "halId_s":"hal-03429442", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"Free Radical Biology and Medicine, 2021, 171, pp.1-10. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.freeradbiomed.2021.05.002\">⟨10.1016/j.freeradbiomed.2021.05.002⟩</a>", "citationFull_s":"Jean-François Goossens, Xavier Thuru, Christian Bailly. Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin. Free Radical Biology and Medicine, 2021, 171, pp.1-10. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.freeradbiomed.2021.05.002\">⟨10.1016/j.freeradbiomed.2021.05.002⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03226670\">⟨hal-03226670⟩</a>", "title_s":["Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin"], "authFullName_s":["Jean-François Goossens", "Xavier Thuru", "Christian Bailly"], "halId_s":"hal-03226670", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"France, Patent n° : WO2021009384. 2021", "citationFull_s":"Xavier Thuru, Bruno Quesnel, Romain Magnez, Régis Millet, Natascha Leleu-Chavain, et al.. NOVEL PYRAZOLONE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS. France, Patent n° : WO2021009384. 2021. <a target=\"_blank\" href=\"https://inserm.hal.science/inserm-04542080\">⟨inserm-04542080⟩</a>", "title_s":["NOVEL PYRAZOLONE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS"], "authFullName_s":["Xavier Thuru", "Bruno Quesnel", "Romain Magnez", "Régis Millet", "Natascha Leleu-Chavain", "Frédérique Klupsch"], "halId_s":"inserm-04542080", "docType_s":"PATENT", "producedDateY_i":2021}, { "citationRef_s":"France, Patent n° : WO2021009384 (A1). 2021", "citationFull_s":"Xavier Thuru, Bruno Quesnel, Magnez Romain, Régis Millet, Natascha Leleu-Chavain, et al.. NOVEL PYRAZOLONE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS. France, Patent n° : WO2021009384 (A1). 2021. <a target=\"_blank\" href=\"https://hal.science/hal-03857440\">⟨hal-03857440⟩</a>", "title_s":["NOVEL PYRAZOLONE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS"], "authFullName_s":["Xavier Thuru", "Bruno Quesnel", "Magnez Romain", "Régis Millet", "Natascha Leleu-Chavain", "Frédérique Klupsch"], "halId_s":"hal-03857440", "docType_s":"PATENT", "producedDateY_i":2021}, { "citationRef_s":"Cancers, 2021, 13 (22), pp.5746. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13225746\">⟨10.3390/cancers13225746⟩</a>", "citationFull_s":"Nicolas Stoup, Maxime Liberelle, Céline Schulz, Sumeyye Cavdarli, Romain Vasseur, et al.. The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis. Cancers, 2021, 13 (22), pp.5746. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13225746\">⟨10.3390/cancers13225746⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03641795\">⟨hal-03641795⟩</a>", "title_s":["The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis"], "authFullName_s":["Nicolas Stoup", "Maxime Liberelle", "Céline Schulz", "Sumeyye Cavdarli", "Romain Vasseur", "Romain Magnez", "Fatima Lahdaoui", "Nicolas Skrypek", "Fabien Peretti", "Frédéric Frénois", "Xavier Thuru", "Patricia Melnyk", "Nicolas Renault", "Nicolas Jonckheere", "Nicolas Lebègue", "Isabelle van Seuningen"], "halId_s":"hal-03641795", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"Cancers, 2021, 13 (12), pp.3034. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13123034\">⟨10.3390/cancers13123034⟩</a>", "citationFull_s":"Christian Bailly, Xavier Thuru, Bruno Quesnel. Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases. Cancers, 2021, 13 (12), pp.3034. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers13123034\">⟨10.3390/cancers13123034⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-03278429\">⟨hal-03278429⟩</a>", "title_s":["Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases"], "authFullName_s":["Christian Bailly", "Xavier Thuru", "Bruno Quesnel"], "halId_s":"hal-03278429", "docType_s":"ART", "producedDateY_i":2021}, { "citationRef_s":"Bioorganic and Medicinal Chemistry, 2020, 28 (10), pp.115463. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bmc.2020.115463\">⟨10.1016/j.bmc.2020.115463⟩</a>", "citationFull_s":"Christian Bailly, Paul-Emile Hecquet, Mostafa Kouach, Xavier Thuru, Jean-Francois Goossens. Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone. Bioorganic and Medicinal Chemistry, 2020, 28 (10), pp.115463. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bmc.2020.115463\">⟨10.1016/j.bmc.2020.115463⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873617\">⟨hal-02873617⟩</a>", "title_s":["Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone"], "authFullName_s":["Christian Bailly", "Paul-Emile Hecquet", "Mostafa Kouach", "Xavier Thuru", "Jean-Francois Goossens"], "halId_s":"hal-02873617", "docType_s":"ART", "producedDateY_i":2020}, { "citationRef_s":"Bio-protocol , 2020, Bio-protocol, 10 (7), <a target=\"_blank\" href=\"https://dx.doi.org/10.21769/bioprotoc.3574\">⟨10.21769/bioprotoc.3574⟩</a>", "citationFull_s":"Magnez Romain, Bryan Thiroux, Morgane Tardy, Bruno Quesnel, Xavier Thuru. Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST). Bio-protocol , 2020, Bio-protocol, 10 (7), <a target=\"_blank\" href=\"https://dx.doi.org/10.21769/bioprotoc.3574\">⟨10.21769/bioprotoc.3574⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03185893\">⟨hal-03185893⟩</a>", "title_s":["Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST)"], "authFullName_s":["Magnez Romain", "Bryan Thiroux", "Morgane Tardy", "Bruno Quesnel", "Xavier Thuru"], "halId_s":"hal-03185893", "docType_s":"ART", "producedDateY_i":2020}, { "citationRef_s":"Bioorganic Chemistry, 2020, 96, pp.103643. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bioorg.2020.103643\">⟨10.1016/j.bioorg.2020.103643⟩</a>", "citationFull_s":"Alina Ghinet, Xavier Thuru, Emilie Floquet, Joëlle Dubois, Amaury Farce, et al.. Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands. Bioorganic Chemistry, 2020, 96, pp.103643. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bioorg.2020.103643\">⟨10.1016/j.bioorg.2020.103643⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873632\">⟨hal-02873632⟩</a>", "title_s":["Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands"], "authFullName_s":["Alina Ghinet", "Xavier Thuru", "Emilie Floquet", "Joëlle Dubois", "Amaury Farce", "Benoit Rigo"], "halId_s":"hal-02873632", "docType_s":"ART", "producedDateY_i":2020}, { "citationRef_s":"NAR Cancer, 2020, 2 (1), pp.zcaa002. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/narcan/zcaa002\">⟨10.1093/narcan/zcaa002⟩</a>", "citationFull_s":"Christian Bailly, Xavier Thuru, Bruno Quesnel. Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times. NAR Cancer, 2020, 2 (1), pp.zcaa002. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/narcan/zcaa002\">⟨10.1093/narcan/zcaa002⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873714\">⟨hal-02873714⟩</a>", "title_s":["Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times"], "authFullName_s":["Christian Bailly", "Xavier Thuru", "Bruno Quesnel"], "halId_s":"hal-02873714", "docType_s":"ART", "producedDateY_i":2020}, { "citationRef_s":"Stem Cells and Development, 2020, 29 (14), pp.919-928. <a target=\"_blank\" href=\"https://dx.doi.org/10.1089/scd.2019.0223\">⟨10.1089/scd.2019.0223⟩</a>", "citationFull_s":"Yasmine S. Touil, Zacharie Segaoula, Xavier Thuru, Sylvie Zouitina, Dominique Tierny, et al.. Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities. Stem Cells and Development, 2020, 29 (14), pp.919-928. <a target=\"_blank\" href=\"https://dx.doi.org/10.1089/scd.2019.0223\">⟨10.1089/scd.2019.0223⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873700\">⟨hal-02873700⟩</a>", "title_s":["Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities"], "authFullName_s":["Yasmine S. Touil", "Zacharie Segaoula", "Xavier Thuru", "Sylvie Zouitina", "Dominique Tierny", "Bruno Quesnel"], "halId_s":"hal-02873700", "docType_s":"ART", "producedDateY_i":2020}, { "citationRef_s":"Archiv der Pharmazie / Chemistry in Life Sciences, 2019, 352 (5), pp.1800227. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/ardp.201800227\">⟨10.1002/ardp.201800227⟩</a>", "citationFull_s":"Liliana Lucescu, Alina Ghinet, Sergiu Shova, Romain Magnez, Xavier Thuru, et al.. Exploring isoxazoles and pyrrolidinones decorated with the 4,6‐dimethoxy‐1,3,5‐triazine unit as human farnesyltransferase inhibitors. Archiv der Pharmazie / Chemistry in Life Sciences, 2019, 352 (5), pp.1800227. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/ardp.201800227\">⟨10.1002/ardp.201800227⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873628\">⟨hal-02873628⟩</a>", "title_s":["Exploring isoxazoles and pyrrolidinones decorated with the 4,6‐dimethoxy‐1,3,5‐triazine unit as human farnesyltransferase inhibitors"], "authFullName_s":["Liliana Lucescu", "Alina Ghinet", "Sergiu Shova", "Romain Magnez", "Xavier Thuru", "Amaury Farce", "Benoit Rigo", "Dalila Belei", "Joëlle Dubois", "Elena Bîcu"], "halId_s":"hal-02873628", "docType_s":"ART", "producedDateY_i":2019}, { "citationRef_s":"Scientific Reports, 2019, 9 (1), <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/s41598-019-53099-0\">⟨10.1038/s41598-019-53099-0⟩</a>", "citationFull_s":"Maxime Liberelle, Romain Magnez, Xavier Thuru, Yamina Bencheikh, Séverine Ravez, et al.. MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis. Scientific Reports, 2019, 9 (1), <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/s41598-019-53099-0\">⟨10.1038/s41598-019-53099-0⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02407901\">⟨hal-02407901⟩</a>", "title_s":["MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis"], "authFullName_s":["Maxime Liberelle", "Romain Magnez", "Xavier Thuru", "Yamina Bencheikh", "Séverine Ravez", "Camille Quenon", "Anne-Sophie Drucbert", "Catherine Foulon", "Patricia Melnyk", "Isabelle Van Seuningen", "Nicolas Lebegue"], "halId_s":"hal-02407901", "docType_s":"ART", "producedDateY_i":2019}, { "citationRef_s":"BMC Cancer, 2018, 18 (1), pp.1219. <a target=\"_blank\" href=\"https://dx.doi.org/10.1186/s12885-018-5114-y\">⟨10.1186/s12885-018-5114-y⟩</a>", "citationFull_s":"Zacharie Segaoula, Aline Primot, Frederic Lepretre, Benoit Hedan, Emmanuel Bouchaert, et al.. Isolation and characterization of two canine melanoma cell lines new models for comparative oncology. BMC Cancer, 2018, 18 (1), pp.1219. <a target=\"_blank\" href=\"https://dx.doi.org/10.1186/s12885-018-5114-y\">⟨10.1186/s12885-018-5114-y⟩</a>. <a target=\"_blank\" href=\"https://univ-rennes.hal.science/hal-01972446\">⟨hal-01972446⟩</a>", "title_s":["Isolation and characterization of two canine melanoma cell lines new models for comparative oncology"], "authFullName_s":["Zacharie Segaoula", "Aline Primot", "Frederic Lepretre", "Benoit Hedan", "Emmanuel Bouchaert", "Kevin Minier", "Laurent Marescaux", "Francois Serres", "Sylvie Galiegue-Zouitina", "Catherine André", "Bruno Quesnel", "Xavier Thuru", "Dominique Tierny"], "halId_s":"hal-01972446", "docType_s":"ART", "producedDateY_i":2018}, { "citationRef_s":"Cancers, 2018, 10 (5), pp.140. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers10050140\">⟨10.3390/cancers10050140⟩</a>", "citationFull_s":"Floriane Gibault, Mathilde Coevoet, Manon Sturbaut, Amaury Farce, Nicolas Renault, et al.. Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface. Cancers, 2018, 10 (5), pp.140. <a target=\"_blank\" href=\"https://dx.doi.org/10.3390/cancers10050140\">⟨10.3390/cancers10050140⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02060686\">⟨hal-02060686⟩</a>", "title_s":["Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface"], "authFullName_s":["Floriane Gibault", "Mathilde Coevoet", "Manon Sturbaut", "Amaury Farce", "Nicolas Renault", "Frédéric Allemand", "Jean-François Guichou", "Anne Sophie Drucbert", "Catherine Foulon", "Romain Magnez", "Xavier Thuru", "Mathieu Corvaisier", "Guillemette Huet", "Philippe Chavatte", "Patricia Melnyk", "Fabrice Bailly", "Philippe Cotelle"], "halId_s":"hal-02060686", "docType_s":"ART", "producedDateY_i":2018}, { "citationRef_s":"Scientific Reports, 2017, 7 (1), pp.17623. <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/s41598-017-17963-1\">⟨10.1038/s41598-017-17963-1⟩</a>", "citationFull_s":"Romain Magnez, Bryan Thiroux, Solenne Taront, Zacharie Segaoula, Bruno Quesnel, et al.. PD-1/PD-L1 binding studies using microscale thermophoresis. Scientific Reports, 2017, 7 (1), pp.17623. <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/s41598-017-17963-1\">⟨10.1038/s41598-017-17963-1⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873635\">⟨hal-02873635⟩</a>", "title_s":["PD-1/PD-L1 binding studies using microscale thermophoresis"], "authFullName_s":["Romain Magnez", "Bryan Thiroux", "Solenne Taront", "Zacharie Segaoula", "Bruno Quesnel", "Xavier Thuru"], "halId_s":"hal-02873635", "docType_s":"ART", "producedDateY_i":2017}, { "citationRef_s":"Journal of Medicinal Chemistry, 2016, 59 (18), pp.8422-8440. <a target=\"_blank\" href=\"https://dx.doi.org/10.1021/acs.jmedchem.6b00847\">⟨10.1021/acs.jmedchem.6b00847⟩</a>", "citationFull_s":"Zacharie Segaoula, Julien Leclercq, Valérie Verones, Nathalie Flouquet, Marie Lecoeur, et al.. Synthesis and Biological Evaluation of N -[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity. Journal of Medicinal Chemistry, 2016, 59 (18), pp.8422-8440. <a target=\"_blank\" href=\"https://dx.doi.org/10.1021/acs.jmedchem.6b00847\">⟨10.1021/acs.jmedchem.6b00847⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02060584\">⟨hal-02060584⟩</a>", "title_s":["Synthesis and Biological Evaluation of N -[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity"], "authFullName_s":["Zacharie Segaoula", "Julien Leclercq", "Valérie Verones", "Nathalie Flouquet", "Marie Lecoeur", "Lionel Ach", "Nicolas Renault", "Amelie Barczyk", "Patricia Melnyk", "Pascal Berthelot", "Xavier Thuru", "Nicolas Lebegue"], "halId_s":"hal-02060584", "docType_s":"ART", "producedDateY_i":2016}, { "citationRef_s":"Clinical Cancer Research, 2015, 21 (23), pp.5314-5323. <a target=\"_blank\" href=\"https://dx.doi.org/10.1158/1078-0432.ccr-14-3174\">⟨10.1158/1078-0432.ccr-14-3174⟩</a>", "citationFull_s":"D. Tierny, F. Serres, Z. Segaoula, I. Bemelmans, E. Bouchaert, et al.. Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma. Clinical Cancer Research, 2015, 21 (23), pp.5314-5323. <a target=\"_blank\" href=\"https://dx.doi.org/10.1158/1078-0432.ccr-14-3174\">⟨10.1158/1078-0432.ccr-14-3174⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873640\">⟨hal-02873640⟩</a>", "title_s":["Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma"], "authFullName_s":["D. Tierny", "F. Serres", "Z. Segaoula", "I. Bemelmans", "E. Bouchaert", "A. Petain", "V. Brel", "S. Couffin", "T. Marchal", "L. Nguyen", "Xavier Thuru", "P. Ferré", "N. Guilbaud", "B. Gomes"], "halId_s":"hal-02873640", "docType_s":"ART", "producedDateY_i":2015}, { "citationRef_s":"Bioorganic and Medicinal Chemistry, 2011, 19 (20), pp.6042-6054. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bmc.2011.08.047\">⟨10.1016/j.bmc.2011.08.047⟩</a>", "citationFull_s":"Alina Ghinet, Benoit Rigo, Jean-Pierre Hénichart, Delphine Le Broc-Ryckewaert, Jean Pommery, et al.. Synthesis and biological evaluation of phenstatin metabolites. Bioorganic and Medicinal Chemistry, 2011, 19 (20), pp.6042-6054. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bmc.2011.08.047\">⟨10.1016/j.bmc.2011.08.047⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873643\">⟨hal-02873643⟩</a>", "title_s":["Synthesis and biological evaluation of phenstatin metabolites"], "authFullName_s":["Alina Ghinet", "Benoit Rigo", "Jean-Pierre Hénichart", "Delphine Le Broc-Ryckewaert", "Jean Pommery", "Nicole Pommery", "Xavier Thuru", "Bruno Quesnel", "Philippe Gautret"], "halId_s":"hal-02873643", "docType_s":"ART", "producedDateY_i":2011}, { "citationRef_s":"Journal of Infectious Diseases, 2008, 197 (7), pp.972-980. <a target=\"_blank\" href=\"https://dx.doi.org/10.1086/528990\">⟨10.1086/528990⟩</a>", "citationFull_s":"Samir Jawhara, Xavier Thuru, Annie Standaert‐vitse, Thierry Jouault, Serge Mordon, et al.. Colonization of Mice by Candida albicans Is Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3. Journal of Infectious Diseases, 2008, 197 (7), pp.972-980. <a target=\"_blank\" href=\"https://dx.doi.org/10.1086/528990\">⟨10.1086/528990⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873647\">⟨hal-02873647⟩</a>", "title_s":["Colonization of Mice by Candida albicans Is Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3"], "authFullName_s":["Samir Jawhara", "Xavier Thuru", "Annie Standaert‐vitse", "Thierry Jouault", "Serge Mordon", "Boualem Sendid", "Pierre Desreumaux", "Daniel Poulain"], "halId_s":"hal-02873647", "docType_s":"ART", "producedDateY_i":2008}, { "citationRef_s":"Gut, 2007, 56 (7), pp.974-81. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2006.105122\">⟨10.1136/gut.2006.105122⟩</a>", "citationFull_s":"Dania Chakass, David Philippe, Edmone Erdual, Sébastien Dharancy, Mathilde Malapel, et al.. micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.. Gut, 2007, 56 (7), pp.974-81. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2006.105122\">⟨10.1136/gut.2006.105122⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00189969\">⟨hal-00189969⟩</a>", "title_s":["micro-Opioid receptor activation prevents acute hepatic inflammation and cell death."], "authFullName_s":["Dania Chakass", "David Philippe", "Edmone Erdual", "Sébastien Dharancy", "Mathilde Malapel", "Caroline Dubuquoy", "Xavier Thuru", "Jérôme Gay-Quéheillard", "Claire Gaveriaux-Ruff", "Pierre Dubus", "Philippe Mathurin", "Brigitte L Kieffer", "Pierre Desreumaux", "Mathias Chamaillard"], "halId_s":"hal-00189969", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"Inflammatory Bowel Diseases, 2007, Inflammatory Bowel Diseases, 13 (5), pp.650. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705005-00026\">⟨10.1097/00054725-200705005-00026⟩</a>", "citationFull_s":"F Gonzalez, L Peyrin-Biroulet, C Rousseaux, Laurent Dubuquoy, Xavier Thuru, et al.. C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease. Inflammatory Bowel Diseases, 2007, Inflammatory Bowel Diseases, 13 (5), pp.650. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705005-00026\">⟨10.1097/00054725-200705005-00026⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03113336\">⟨hal-03113336⟩</a>", "title_s":["C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease"], "authFullName_s":["F Gonzalez", "L Peyrin-Biroulet", "C Rousseaux", "Laurent Dubuquoy", "Xavier Thuru", "C Decourcelle", "L Gambiez", "Christel Neut", "J Colombel", "Pierre Desreumaux"], "halId_s":"hal-03113336", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"Journal of Crohn's and Colitis, 2007, 1 (1), pp.49. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s1873-9954(07)70188-x\">⟨10.1016/s1873-9954(07)70188-x⟩</a>", "citationFull_s":"F. Gonzalez, L. Peyrin-Biroulet, C. Rousseaux, Xavier Thuru, C. Decourcelle, et al.. P176 C-Reactive Protein (crp), a novel adipocytokine overexpressed in Mesenteric fat in Crohn's disease. Journal of Crohn's and Colitis, 2007, 1 (1), pp.49. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s1873-9954(07)70188-x\">⟨10.1016/s1873-9954(07)70188-x⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873662\">⟨hal-02873662⟩</a>", "title_s":["P176 C-Reactive Protein (crp), a novel adipocytokine overexpressed in Mesenteric fat in Crohn's disease"], "authFullName_s":["F. Gonzalez", "L. Peyrin-Biroulet", "C. Rousseaux", "Xavier Thuru", "C. Decourcelle", "L. Gambiez", "A. Saudemont", "C. Neut", "L. Penicaud", "J.B. Saulnier", "J.-F. Colombel", "P. Desreumaux"], "halId_s":"hal-02873662", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"Journal of Crohn's and Colitis, 2007, 1 (1), pp.2. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s1873-9954(07)70004-6\">⟨10.1016/s1873-9954(07)70004-6⟩</a>", "citationFull_s":"L. Peyrin-Biroulet, Xavier Thuru, C. Vignal, L. Dubuquoy, E. Merour, et al.. Peroxisome Proliferator-Activated Receptor Gamma Functions As An Antibacterial Factor. Journal of Crohn's and Colitis, 2007, 1 (1), pp.2. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s1873-9954(07)70004-6\">⟨10.1016/s1873-9954(07)70004-6⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873659\">⟨hal-02873659⟩</a>", "title_s":["Peroxisome Proliferator-Activated Receptor Gamma Functions As An Antibacterial Factor"], "authFullName_s":["L. Peyrin-Biroulet", "Xavier Thuru", "C. Vignal", "L. Dubuquoy", "E. Merour", "E. Erdual", "C. Neut", "P. Chavatte", "A. Darfeuille-Michaud", "J.F. Colombel", "P. Desreumaux", "M. Chamaillard"], "halId_s":"hal-02873659", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"Nature Medicine, 2007, 13 (1), pp.35-37. <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/nm1521\">⟨10.1038/nm1521⟩</a>", "citationFull_s":"Christel Rousseaux, Xavier Thuru, Agathe Gelot, Nicolas Barnich, Christel Neut, et al.. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nature Medicine, 2007, 13 (1), pp.35-37. <a target=\"_blank\" href=\"https://dx.doi.org/10.1038/nm1521\">⟨10.1038/nm1521⟩</a>. <a target=\"_blank\" href=\"https://hal.inrae.fr/hal-02667010\">⟨hal-02667010⟩</a>", "title_s":["Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors"], "authFullName_s":["Christel Rousseaux", "Xavier Thuru", "Agathe Gelot", "Nicolas Barnich", "Christel Neut", "Laurent Dubuquoy", "Caroline Dubuquoy", "Emilie Mérour", "Karen Geboes", "Mathias Chamaillard", "Arthur Ouwehand", "Greg Leyer", "Didier Carcano", "Jean-Fréderic Colombel", "Denis Ardid", "Pierre Desreumaux"], "halId_s":"hal-02667010", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"Inflammatory Bowel Diseases, 2007, 13 (supplement), pp.650. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705001-00026\">⟨10.1097/00054725-200705001-00026⟩</a>", "citationFull_s":"F. Gonzalez, L. Peyrin-Biroulet, C. Rousseaux, L. Dubuquoy, Xavier Thuru, et al.. C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease. Inflammatory Bowel Diseases, 2007, 13 (supplement), pp.650. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705001-00026\">⟨10.1097/00054725-200705001-00026⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873652\">⟨hal-02873652⟩</a>", "title_s":["C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease"], "authFullName_s":["F. Gonzalez", "L. Peyrin-Biroulet", "C. Rousseaux", "L. Dubuquoy", "Xavier Thuru", "C Decourcelle", "L. Gambiez", "C. Neut", "J. Colombel", "P. Desreumaux"], "halId_s":"hal-02873652", "docType_s":"ART", "producedDateY_i":2007}, { "citationRef_s":"5. Annual Advances in the Inflammatory Bowel Diseases, Dec 2006, Miami (Florida), United States. 13 (Supplement 5), pp.652-653, 2007, Abstracts from the 2006 CCFA National Research and Clinical Conference, 5th Annual Advances in the Inflammatory Bowel Diseases, Dec. 1‐3, 2006, Miami, FL. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705001-00035\">⟨10.1097/00054725-200705001-00035⟩</a>", "citationFull_s":"C. Rousseaux, Xavier Thuru, A. Gelot, N. Barnich, C. Neut, et al.. Induction of mu opioid and cannabinoid receptors by probiotics: A new mechanism of regulation of visceral pain perception. 5. Annual Advances in the Inflammatory Bowel Diseases, Dec 2006, Miami (Florida), United States. 13 (Supplement 5), pp.652-653, 2007, Abstracts from the 2006 CCFA National Research and Clinical Conference, 5th Annual Advances in the Inflammatory Bowel Diseases, Dec. 1‐3, 2006, Miami, FL. <a target=\"_blank\" href=\"https://dx.doi.org/10.1097/00054725-200705001-00035\">⟨10.1097/00054725-200705001-00035⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873654\">⟨hal-02873654⟩</a>", "title_s":["Induction of mu opioid and cannabinoid receptors by probiotics: A new mechanism of regulation of visceral pain perception"], "authFullName_s":["C. Rousseaux", "Xavier Thuru", "A. Gelot", "N. Barnich", "C. Neut", "C. Dubuquoy", "A. Ouwehand", "D. Ardid", "D. Carcano", "P. Desreumaux"], "halId_s":"hal-02873654", "docType_s":"POSTER", "producedDateY_i":2006}, { "citationRef_s":"Gut, 2006, 55 (9), pp.1341-1349. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2006.093484\">⟨10.1136/gut.2006.093484⟩</a>", "citationFull_s":"Xavier Thuru, L. Dubuquoy. PPAR as a new therapeutic target in inflammatory bowel diseases. Gut, 2006, 55 (9), pp.1341-1349. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2006.093484\">⟨10.1136/gut.2006.093484⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873664\">⟨hal-02873664⟩</a>", "title_s":["PPAR as a new therapeutic target in inflammatory bowel diseases"], "authFullName_s":["Xavier Thuru", "L. Dubuquoy"], "halId_s":"hal-02873664", "docType_s":"ART", "producedDateY_i":2006}, { "citationRef_s":"Gut, 2006, 55 (6), pp.815-823. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2005.080887\">⟨10.1136/gut.2005.080887⟩</a>", "citationFull_s":"Xavier Thuru, D Philippe. Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation. Gut, 2006, 55 (6), pp.815-823. <a target=\"_blank\" href=\"https://dx.doi.org/10.1136/gut.2005.080887\">⟨10.1136/gut.2005.080887⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873665\">⟨hal-02873665⟩</a>", "title_s":["Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation"], "authFullName_s":["Xavier Thuru", "D Philippe"], "halId_s":"hal-02873665", "docType_s":"ART", "producedDateY_i":2006}, { "citationRef_s":"Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, 2004, 28 (1), pp.97. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s0399-8320(04)94859-2\">⟨10.1016/s0399-8320(04)94859-2⟩</a>", "citationFull_s":"Pierre Desreumaux, Xavier Thuru, David Philippe. Cannabis : des nouvelles fonctions anti-diarrhéiques et anti-cancéreuses. Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, 2004, 28 (1), pp.97. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/s0399-8320(04)94859-2\">⟨10.1016/s0399-8320(04)94859-2⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02873668\">⟨hal-02873668⟩</a>", "title_s":["Cannabis : des nouvelles fonctions anti-diarrhéiques et anti-cancéreuses"], "authFullName_s":["Pierre Desreumaux", "Xavier Thuru", "David Philippe"], "halId_s":"hal-02873668", "docType_s":"ART", "producedDateY_i":2004}] }}