nicolas Willand
Publications
Compte-rendu et recension critique d'ouvrage
-
Faion, Léo
;
Djaout, Kamel
;
Frita, Rosangela
;
Pintiala, Catalin
;
Cantrelle, Francois-Xavier
;
Moune, Martin
;
Vandeputte, Alexandre
;
Bourbiaux, Kevin
;
Piveteau, Catherine
;
Herledan, Adrien
;
Biela, Alexandre
;
Leroux, Florence
;
Kremer, Laurent
;
Blaise, Mickael
;
Tanina, Abdalkarim
;
Wintjens, René
;
Hanoulle, Xavier
;
Déprez, Benoit
;
Willand, nicolas
;
Baulard, Alain
;
Flipo, Marion
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening
Elsevier, 2020, , https://dx.doi.org/10.1016/j.ejmech.2020.112440
-
Prevet, Hugues
;
Moune, Martin
;
Tanina, Abdalkarim
;
Kemmer, Christian
;
Herledan, Adrien
;
Frita, Rosangela
;
Wohlkönig, Alexandre
;
Bourotte, Marilyne
;
Villemagne, Baptiste
;
Leroux, Florence
;
Gitzinger, Marc
;
Baulard, Alain
;
Déprez, Benoit
;
Wintjens, René
;
Willand, nicolas
;
Flipo, Marion
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2
Elsevier, 2019, , https://dx.doi.org/10.1016/j.ejmech.2019.02.023
-
Machelart, Arnaud
;
Salzano, Giuseppina
;
Li, Xue
;
Demars, Aurore
;
Debrie, Anne-Sophie
;
Menendez-Miranda, Mario
;
Pancani, Elisabetta
;
Jouny, Samuel
;
Hoffmann, Eik
;
Deboosere, Nathalie
;
Belhaouane, Imène
;
Rouanet, Carine
;
Simar, Sophie
;
Talahari, Smaïl
;
Giannini, Valerie
;
Villemagne, Baptiste
;
Flipo, Marion
;
Brosch, Roland
;
Nesslany, Fabrice
;
Déprez, Benoit
;
Muraille, Eric
;
Locht, Camille
;
Baulard, Alain
;
Willand, nicolas
;
Majlessi, Laleh
;
Gref, Ruxandra
;
Brodin, Priscille
Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis
American Chemical Society, 2019, , https://dx.doi.org/10.1021/acsnano.8b07902
-
Pastor, Alexandra
;
Machelart, Arnaud
;
Li, Xue
;
Willand, nicolas
;
Baulard, Alain
;
Brodin, Priscille
;
Gref, Ruxandra
;
Desmaele, Didier
A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation
Royal Society of Chemistry, 2019, , https://dx.doi.org/10.1039/c9ob00680j
-
Costa-Gouveia, Joana
;
Pancani, Elisabetta
;
Jouny, Samuel
;
Machelart, Arnaud
;
Delorme, Vincent
;
Salzano, Giuseppina
;
Iantomasi, Raffaella
;
Piveteau, Catherine
;
Queval, Christophe
;
Song, Ok-Ryul
;
Flipo, Marion
;
Déprez, Benoit
;
Saint-André, Jean-Paul
;
Hureaux, José
;
Majlessi, Laleh
;
Willand, nicolas
;
Baulard, Alain
;
Brodin, Priscille
;
Gref, Ruxandra
Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles
Nature Publishing Group, 2018, , https://dx.doi.org/10.1038/s41598-018-25177-2
-
Costa-Gouveia, Joana
;
Pancani, Elisabetta
;
Jouny, Samuel
;
Machelart, Arnaud
;
Delorme, Vincent
;
Salzano, Giuseppina
;
Iantomasi, Raffaella
;
Piveteau, Catherine
;
Queval, Christophe
;
Song, Ok-Ryul
;
Flipo, Marion
;
Déprez, Benoit
;
Saint-Andre, Jean-Paul
;
Hureaux, José
;
Majlessi, Laleh
;
Willand, nicolas
;
Baulard, Alain
;
Brodin, Priscille
;
Gref, Ruxandra
Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles
Nature Publishing Group, 2017, , https://dx.doi.org/10.1038/s41598-017-05453-3
-
Salzano, Giuseppina
;
Wankar, Jitendra
;
Ottani, Stefano
;
Villemagne, Baptiste
;
Baulard, Alain
;
Willand, nicolas
;
Brodin, Priscille
;
Manet, Ilse
;
Gref, Ruxandra
Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs
Elsevier, 2017, , https://dx.doi.org/10.1016/j.ijpharm.2017.05.030
-
Blondiaux, Nicolas
;
Moune, Martin
;
Desroses, Matthieu
;
Frita, Rosangela
;
Flipo, Marion
;
Mathys, Vanessa
;
Soetaert, Karine
;
Kiass, Mehdi
;
Delorme, Vincent
;
Djaout, Kamel
;
Trebosc, Vincent
;
Kemmer, Christian
;
Wintjens, René
;
Wohlkönig, Alexandre
;
Antoine, Rudy
;
Huot, Ludovic
;
Hot, David
;
Coscolla, Mireia
;
Feldmann, Julia
;
Gagneux, Sebastien
;
Locht, Camille
;
Brodin, Priscille
;
Gitzinger, Marc
;
Déprez, Benoit
;
Willand, nicolas
;
Baulard, Alain
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
American Association for the Advancement of Science (AAAS), 2017, , https://dx.doi.org/10.1126/science.aag1006
-
Tatum, Natalie
;
Liebeschuetz, John
;
Cole, Jason
;
Frita, Rosangela
;
Herledan, Adrien
;
Baulard, Alain
;
Willand, nicolas
;
Pohl, Ehmke
New active leads for tuberculosis booster drugs by structure-based drug discovery
Royal Society of Chemistry, 2017, , https://dx.doi.org/10.1039/c7ob00910k
-
Tatum, Natalie
;
Villemagne, Baptiste
;
Willand, nicolas
;
Deprez, Benoit
;
Liebeschuetz, John
;
Baulard, Alain
;
Pohl, Ehmke
Structural and docking studies of potent ethionamide boosters
International Union of Crystallography, 2013, , https://dx.doi.org/10.1107/S0108270113028126
-
Flipo, Marion
;
Willand, nicolas
;
Lecat-Guillet, Nathalie
;
Hounsou, Candide
;
Desroses, Matthieu
;
Leroux, Florence
;
Lens, Zoé
;
Villeret, Vincent
;
Wohlkönig, Alexandre
;
Wintjens, René
;
Christophe, Thierry
;
Kyoung Jeon, Hee
;
Locht, Camille
;
Brodin, Priscille
;
Baulard, Alain
;
Déprez, Benoit
Discovery of Novel N -Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis
American Chemical Society, 2012, , https://dx.doi.org/10.1021/jm300377g
-
Carette, Xavier
;
Blondiaux, Nicolas
;
Willery, Eve
;
Hoos, Sylviane
;
Lecat-Guillet, Nathalie
;
Lens, Zoé
;
Wohlkönig, Alexandre
;
Wintjens, René
;
Soror, Sameh
;
Frénois, Frédéric
;
Dirié, Bertrand
;
Villeret, Vincent
;
England, Patrick
;
Lippens, Guy
;
Deprez, Benoit
;
Locht, Camille
;
Willand, nicolas
;
Baulard, Alain
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands
Oxford University Press, 2011, , https://dx.doi.org/10.1093/nar/gkr1113
-
Flipo, Marion
;
Desroses, Matthieu
;
Lecat-Guillet, Nathalie
;
Villemagne, Baptiste
;
Blondiaux, Nicolas
;
Leroux, Florence
;
Piveteau, Catherine
;
Mathys, Vanessa
;
Flament, Marie-Pierre
;
Siepmann, Juergen
;
Villeret, Vincent
;
Wohlkönig, Alexandre
;
Wintjens, René
;
Soror, Sameh
;
Christophe, Thierry
;
Jeon, Hee Kyoung
;
Locht, Camille
;
Brodin, Priscille
;
Déprez, Benoit
;
Baulard, Alain
;
Willand, nicolas
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
American Chemical Society, 2011, , https://dx.doi.org/10.1021/jm200825u
-
Bonnel, David
;
Legouffe, Raphael
;
Willand, nicolas
;
Baulard, Alain
;
Hamm, Gregory
;
Deprez, Benoit
;
Stauber, Jonathan
MALDI imaging techniques dedicated to drug-distribution studies
Future Science, 2011, , https://dx.doi.org/10.4155/bio.11.88
-
Flipo, Marion
;
Desroses, Matthieu
;
Lecat-Guillet, Nathalie
;
Dirié, Bertrand
;
Carette, Xavier
;
Leroux, Florence
;
Piveteau, Catherine
;
Demirkaya, Fatma
;
Lens, Zoé
;
Rucktooa, Prakash
;
Villeret, Vincent
;
Christophe, Thierry
;
Jeon, Hee Kyoung
;
Locht, Camille
;
Brodin, Priscille
;
Déprez, Benoit
;
Baulard, Alain
;
Willand, nicolas
Ethionamide Boosters: Synthesis, Biological Activity, and Structure−Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors
American Chemical Society, 2011, , https://dx.doi.org/10.1021/jm200076a
-
Willand, nicolas
;
Desroses, Matthieu
;
Toto, Patrick
;
Dirié, Bertrand
;
Lens, Zoé
;
Villeret, Vincent
;
Rucktooa, Prakash
;
Locht, Camille
;
Baulard, Alain
;
Deprez, Benoit
Exploring Drug Target Flexibility Using in Situ Click Chemistry: Application to a Mycobacterial Transcriptional Regulator
American Chemical Society, 2010, , https://dx.doi.org/10.1021/cb100177g
-
Willand, nicolas
;
Dirié, Bertrand
;
Carette, Xavier
;
Bifani, Pablo
;
Singhal, Amit
;
Desroses, Matthieu
;
Leroux, Florence
;
Willery, Eve
;
Mathys, Vanessa
;
Déprez-Poulain, Rebecca
;
Delcroix, Guy
;
Frénois, Frédéric
;
Aumercier, Marc
;
Locht, Camille
;
Villeret, Vincent
;
Déprez, Benoit
;
Baulard, Alain
Synthetic EthR inhibitors boost antituberculous activity of ethionamide
Nature Publishing Group, 2009, , https://dx.doi.org/10.1038/nm.1950
Partie d'ouvrage
-
Willand, nicolas
;
Flipo, Marion
;
Villemagne, Baptiste
;
Baulard, Alain
;
Deprez, Benoit
Recent advances in the design of inhibitors of mycobacterial transcriptional regulators to boost thioamides anti-tubercular activity and circumvent acquired-resistance
Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis, 2019, , https://dx.doi.org/10.1016/bs.armc.2019.06.003