nicolas Willand
Publications
Article dans une revue scientifique
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Ruggieri, Francesca
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HANCE, PHILIPPE
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Gioia, Bruna
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Biela, Alexandre
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Roussel, Pascal
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Hilbert, Jean-Louis
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willand, nicolas
A Three-Step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from Cichorium intybus L. Roots and Semisynthesis of Chicory STLs Standards
Pharmaceuticals, MDPI, 2023 , https://dx.doi.org/10.3390/ph16050771
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Tangara, Salia
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Faïon, Léo
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Piveteau, Catherine
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Capet, Frederic
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Godelier, Romain
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Michel, Marion
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Flipo, Marion
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Deprez, Benoit
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willand, nicolas
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Villemagne, Baptiste
Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization
Pharmaceuticals, MDPI, 2023 , https://dx.doi.org/10.3390/ph16030413
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Pastor, Alexandra
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Machelart, Arnaud
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Li, Xue
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willand, nicolas
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Baulard, Alain
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Brodin, Priscille
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Gref, Ruxandra
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Desmaele, Didier
A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2019 , https://dx.doi.org/10.1039/C9OB00680J
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Prevet, Hugues
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Flipo, Marion
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Roussel, Pascal
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Deprez, Benoit
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willand, nicolas
Microwave-assisted synthesis of functionalized spirohydantoins as 3-D privileged fragments for scouting the chemical space
Tetrahedron Letters, 2016 , https://dx.doi.org/10.1016/j.tetlet.2016.05.065
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Jida, M.
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Soueidan, M.
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willand, nicolas
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Agbossou-Niedercorn, Francine
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Pelinski, Lydie
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Laconde, G.
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Deprez-Poulain, Rebecca
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Deprez, Benoit
A facile and rapid synthesis of N-benzyl-2-substituted piperazines
Tetrahedron Lett., 2015 , https://dx.doi.org/10.1016/j.tetlet.2011.02.011
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Flipo, Marion
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Desroses, M.
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Lecat-Guillet, N.
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Villemagne, Baptiste
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Blondiaux, N.
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Leroux, Florence
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Piveteau, Catherine
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Mathys, V.
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Leterme Flament, Marie-Pierre
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Siepmann, Juergen
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Villeret, V.
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Wohlkonig, A.
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Wintjens, R.
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Soror, S. H.
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Christophe, T.
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Jeon, H. K.
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Locht, Camille
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Brodin, Priscille
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Deprez, Benoit
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Baulard, Alain
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willand, nicolas
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
J. Med. Chem., 2015 , https://dx.doi.org/10.1021/jm200825u
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Villemagne, Baptiste
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Flipo, Marion
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Blondiaux, Nicolas
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Crauste, Céline
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Malaquin, Sandra
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Leroux, Florence
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Piveteau, Catherine
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Villeret, Vincent
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Brodin, Priscille
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Villoutreix, Bruno O.
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Sperandio, Olivier
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Soror, Sameh H.
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Wohlkönig, Alexandre
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Wintjens, René
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Deprez, Benoit
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Baulard, Alain
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willand, nicolas
Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches
Journal of medicinal chemistry, 2014 , https://dx.doi.org/10.1021/jm500422b
Compte-rendu et recension critique d'ouvrage
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Mosheim, Juan Rodriguez
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Ruggieri, Francesca
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Humeau, Catherine
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Hance, Philippe
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willand, nicolas
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Hilbert, Jean-Louis
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Heuson, Egon
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Froidevaux, Rénato
O-acylation régiosélective biocatalytique des lactones sesquiterpéniques de la chicorée : une voie vers de nouveaux dérivés esters
Wiley-VCH Verlag, 2024, , https://dx.doi.org/10.1002/cbic.202300722
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Vieira Da Cruz, Anais
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Jiménez-Castellanos, Juan-Carlos
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Börnsen, Clara
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Van Maele, Laurye
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Compagne, Nina
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Pradel, Elizabeth
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Müller, Reinke
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Meurillon, Virginie
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Soulard, Daphnée
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Piveteau, Catherine
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Biela, Alexandre
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Dumont, Julie
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Leroux, Florence
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Deprez, Benoit
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Willand, nicolas
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Pos, Klaas
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Frangakis, Achilleas
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Hartkoorn, Ruben
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Flipo, Marion
Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae
Wiley Open Access, 2023, , https://dx.doi.org/10.1038/s44321-023-00007-9
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Gioia, Bruna
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Ruggieri, Francesca
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Biela, Alexandre
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Landry, Valérie
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Roussel, Pascal
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Leroux, Florence
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Hartkoorn, Ruben
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Willand, nicolas
Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis
MDPI, 2023, , https://dx.doi.org/10.3390/ijms242417395
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Compagne, Nina
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Jiménez-Castellanos, Juan-Carlos
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Meurillon, Virginie
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Pradel, Elizabeth
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Vieira Da Cruz, Anais
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Piveteau, Catherine
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Biela, Alexandre
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Eveque, Maxime
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Leroux, Florence
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Deprez, Benoit
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Willand, nicolas
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Hartkoorn, Ruben
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Flipo, Marion
Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump
Elsevier, 2023, , https://dx.doi.org/10.1016/j.ejmech.2023.115630
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Faïon, Léo
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Djaout, Kamel
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Pintiala, Catalin
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Piveteau, Catherine
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Leroux, Florence
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Biela, Alexandre
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Slupek, Stéphanie
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Antoine, Rudy
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Záhorszká, Monika
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Cantrelle, Francois-Xavier
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Hanoulle, Xavier
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Korduláková, Jana
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Deprez, Benoit
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Willand, nicolas
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Baulard, Alain
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Flipo, Marion
Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification
MDPI, 2023, , https://dx.doi.org/10.3390/ph16030335
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Faïon, Léo
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Djaout, Kamel
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Pintiala, Catalin
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Piveteau, Catherine
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Leroux, Florence
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Biela, Alexandre
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Slupek, Stéphanie
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Antoine, Rudy
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Záhorszká, Monika
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Cantrelle, Francois-Xavier
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Hanoulle, Xavier
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Korduláková, Jana
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Deprez, Benoit
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Willand, nicolas
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Baulard, Alain
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Flipo, Marion
Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification
MDPI, 2023, , https://dx.doi.org/10.3390/ph16030335
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Dam, Sushovan
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Tangara, Salia
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Hamela, Claire
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Hattabi, Theo
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Faïon, Léo
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Carre, Paul
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Antoine, Rudy
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Herledan, Adrien
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Leroux, Florence
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Piveteau, Catherine
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Eveque, Maxime
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Flipo, Marion
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Deprez, Benoit
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Kremer, Laurent
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Willand, nicolas
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Villemagne, Baptiste
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Hartkoorn, Ruben
Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases
American Chemical Society, 2022, , https://dx.doi.org/10.1021/acs.jmedchem.2c01493
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Flipo, Marion
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Frita, Rosangela
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Bourotte, Marilyne
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Martínez-Martínez, María
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Boesche, Markus
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Boyle, Gary
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Derimanov, Geo
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Drewes, Gerard
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Gamallo, Pablo
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Ghidelli-Disse, Sonja
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Gresham, Stephanie
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Jiménez, Elena
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de Mercado, Jaime
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Pérez-Herrán, Esther
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Porras-de Francisco, Esther
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Rullas, Joaquín
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Casado, Patricia
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Leroux, Florence
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Piveteau, Catherine
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Kiass, Mehdi
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Mathys, Vanessa
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Soetaert, Karine
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Megalizzi, Véronique
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Tanina, Abdalkarim
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Wintjens, René
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Antoine, Rudy
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Brodin, Priscille
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Delorme, Vincent
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Moune, Martin
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Djaout, Kamel
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Slupek, Stéphanie
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Kemmer, Christian
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Gitzinger, Marc
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Ballell, Lluis
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Mendoza-Losana, Alfonso
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Lociuro, Sergio
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Déprez, Benoît
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Barros-Aguirre, David
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Remuiñán, Modesto
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Willand, nicolas
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Baulard, Alain
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis
American Association for the Advancement of Science (AAAS), 2022, , https://dx.doi.org/10.1126/scitranslmed.aaz6280
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Antraygues, Kevin
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Compagne, Nina
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Ruggieri, Francesca
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Djaout, Kamel
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Edoo, Zainab
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Eveque, Maxime
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Faïon, Léo
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Gioia, Bruna
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Tangara, Salia
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Vieira Da Cruz, Anais
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Villemagne, Baptiste
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Flipo, Marion
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Baulard, Alain
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Willand, nicolas
On the Hunt for Next-Generation Antimicrobial Agents: An Online Symposium Organized Jointly by the French Society for Medicinal Chemistry (Société de Chimie Thérapeutique) and the French Microbiology Society (Société Française de Microbiologie) on 9–10 December 2021
MDPI, 2022, , https://dx.doi.org/10.3390/ph15040388
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Plé, Coline
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Tam, Heng-Keat
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Vieira Da Cruz, Anais
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Compagne, Nina
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Jiménez-Castellanos, Juan-Carlos
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Müller, Reinke
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Pradel, Elizabeth
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Foong, Wuen Ee
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Malloci, Giuliano
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Ballée, Alexia
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Kirchner, Moritz
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Moshfegh, Parisa
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Herledan, Adrien
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Herrmann, Andrea
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Deprez, Benoit
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Willand, nicolas
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Vargiu, Attilio Vittorio
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Pos, Klaas
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Flipo, Marion
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Hartkoorn, Ruben
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps
Nature Publishing Group, 2022, , https://dx.doi.org/10.1038/s41467-021-27726-2
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Moureu, Sophie
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Caradec, Thibault
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Trivelli, Xavier
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Drobecq, Hervé
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Beury, Delphine
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Bouquet, Peggy
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Caboche, Segolene
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Desmecht, Eva
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Maurier, Florence
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Muharram, Ghaffar
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Villemagne, Baptiste
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Herledan, Adrien
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Hot, David
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Willand, nicolas
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Hartkoorn, Ruben Christiaan
Rubrolone production by Dactylosporangium vinaceum: biosynthesis, modulation and possible biological function
Springer Verlag, 2021, , https://dx.doi.org/10.1007/s00253-021-11404-w
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Faion, Léo
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Djaout, Kamel
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Frita, Rosangela
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Pintiala, Catalin
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Cantrelle, Francois-Xavier
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Moune, Martin
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Vandeputte, Alexandre
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Bourbiaux, Kevin
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Piveteau, Catherine
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Herledan, Adrien
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Biela, Alexandre
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Leroux, Florence
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Kremer, Laurent
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Blaise, Mickael
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Tanina, Abdalkarim
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Wintjens, René
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Hanoulle, Xavier
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Déprez, Benoit
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Willand, nicolas
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Baulard, Alain
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Flipo, Marion
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening
Elsevier, 2020, , https://dx.doi.org/10.1016/j.ejmech.2020.112440