Dascălu AE, Furman C, Lancel S, Lipka E, Liberelle M, Boulanger E, Ghinet A. Ultrasound-Assisted Synthesis of Pyrazoline Derivatives as Potential Antagonists of RAGE-Mediated Pathologies: Insights from SAR Studies and Biological Evaluations. ChemMedChem. 2025 Jan 2;20(1):e202400527. doi: 10.1002/cmdc.202400527. Epub 2024 Nov 5.

Toulotte F, Coevoet M, Liberelle M, Bailly F, Zagiel B, Gelin M, Allemand F, Fourquet P, Melnyk P, Guichou JF, Cotelle P,
Towards the design of ligands of the internal pocket TEADs C-terminal domain. Eur J Med Chem, 2024, 282:117026.

Iannotta L, Fasiczka R, Favetta G, Zhao Y, Giusto E, Dall'Ara E, Wei J, Ho FY, Ciriani C, Cogo S, Tessari I, Iaccarino C, Liberelle M, Bubacco L, Taymans JM, Manzoni C, Kortholt A, Civiero L, Hilfiker S, Lu ML, Greggio E. PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner. Cell Death Dis. 2024 Oct 17;15(10):752. doi: 10.1038/s41419-024-07124-4.

Morez M, Lara Ordóñez AJ, Melnyk P, Liberelle M, Lebègue N, Taymans JM. Leucine-rich repeat kinase 2 (LRRK2) inhibitors for Parkinson's disease: a patent review of the literature to date. Expert Opin Ther Pat. 2024 Sep;34(9):773-788. doi: 10.1080/13543776.2024.2378076. Epub 2024 Jul 19.

Entrena JM, Artacho-Cordón A, Ravez S, Liberelle M, Melnyk P, Toledano-Pinedo M, Almendros P, Cobos EJ, Marco-Contelles J. The proof of concept of 2-{3-[N-(1-benzylpiperidin-4-yl)propyl]amino}-6-[N-methyl-N-(prop-2-yn-1-yl)amino]-4-phenylpyridine-3,5-dicarbonitrile for the therapy of neuropathic pain. Bioorg Chem. 2024 Sep;150:107537. doi: 10.1016/j.bioorg.2024.107537. Epub 2024 Jun 6.

Laversin A, Dufossez R, Bolteau R, Duroux R, Ravez S, Hernandez-Tapia S, Fossart M, Coevoet M, Liberelle M, Yous S, Lebègue N, Melnyk P. Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists. Molecules. 2024 Aug 14;29(16):3847. doi: 10.3390/molecules29163847.

Stoup N, Liberelle M, Lebègue N, Van Seuningen I. Emerging paradigms and recent progress in targeting ErbB in cancers. Trends Pharmacol Sci. 2024 Jun;45(6):552-576. doi: 10.1016/j.tips.2024.04.009. Epub 2024 May 25.

Boutin JA, Liberelle M, Yous S, Ferry G, Nepveu F.
Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems. J Pineal Res, 2023, accepted.

Petrova L, Gergov N, Stoup M, Zapryanova S, Van Damme EJM, Lebègue N, Liberelle M, Zasheva D, Bogoeva V. Jacalin-Curcumin Complex Sensitizes the Breast Cancer MDA-MB-231 Cell Line. Int J Mol Sci. 2023 Dec 12;24(24):17399. doi: 10.3390/ijms242417399.

Bolteau R, Duroux R, Laversin A, Vreulz B, Shiriaeva A, Stauch B, Han G-W, Cherezov V, Renault N, Barczyk A, Ravez S, Coevoet M, Melnyk P, Liberelle M, Yous S.
High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists, Eur J Med Chem, 2022, 241, 114620.

Kozlova A, Thabault L, Dauguet N , Deskeuvre M , Stroobant V , Pilotte L , Liberelle M , Van den Eynde B, Frédérick R.
Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 23-dioxygenase, Eur J Med Chem, 2022, 227, 113892.

Liberelle M, Toulotte F, Renault N, Gelin M, Allemand F, Melnyk P, Guichou J-F, Cotelle P.
Towards the design of selective ligands of TEAD C-terminal domain, J Med Chem, 2022, 65, 5926-5940.

Marchand A, Sarchione A, Athanasopoulos P-S, Roy H-B, Goveas L, Magnez R, Drouyer M, Emanuele M, Ho F-Y, Liberelle M, Melnyk P, Lebègue N, Thuru X, Nichols R-J, Greggio E, Kortholt A, Galli T, Chartier-Harlin M-C, Taymans J-M.
A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively, Cells, 2022, 11(6), 1018.

Thabault L, Brustenga C, Savoyen P, Van Gysel M, Wouters J, Sonveaux P, Frédérick R, Liberelle M.
Discovery of small molecules interacting at lactate dehydrogenases tetrameric interface using a biophysical screening cascade, Eur J Med Chem, 2022, 230, 114102.

Ettaoussi M, Laversin A, Vreulz B, Rami M, Lebègue N, Delagrange P, Caignard D-H, Melnyk P, Liberelle M, Yous S.
Synthesis and SAR studies of Novel Isoquinoline and Tetrahydroisoquinoline Derivatives as Melatonin Receptor Ligands, Chem Med Chem, 2021, 17(3), e202100658.

Kozlova A, Thabault L, Liberelle M, Klaessens S, Prevost J, Mathieu C, Pilotte L, Stroobant V, Van den Eynde B, Frédérick R.
Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 23-Dioxygenase, J Med Chem, 2021, 64(15), 10967–10980.

Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frenois F, Thuru X, Melnyk P, Renault N, Jonckherre N, Lebègue N, Van Seuningen I.
The EGF domains of MUC4 oncomucin mediate HER2 binding affinity and promote pancreatic cancer cell tumorigenesis, Cancers, 2021, 13(22), 5746.

Sturbaut M, Bailly F, Coevoet M, Sileo P, Pugniere M, Liberelle M, Magnez R, Thuru X, Chartier-Harlin M-C, Melnyk P, Gelin M, Allemand F, Guichou JF, Cotelle P.
Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors, Eur J Med Chem, 2021, 226, 113835-849.

Thabault L, Liberelle M, Frédérick R.
Targeting proteins self-association in drug design, Drug Discov Today, 2021, 26(5), 1148-63

Thabault L, Liberelle M, Koruza K, Yildiz E, Joudiou N, Messens J, Brisson L, Wouters J, Sonveaux P, Frédérick R.
Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides, J Biol Chem, 2021, 296, 100422.

Liberelle M, Jonckheere N, Melnyk P, Van Seuningen I, Lebègue N.
EGF-containing membrane-bound Mucins : a hidden ErbB2 signaling pathway ? J Med Chem, 2020, 63(10), 5074-5088.

Thabault L, Brisson L, Brustenga C, Martinez Gache SA, Prévost J, Kozlova A, Spillier Q, Liberelle M, Benyahia Z, Messens J, Copetti T, Sonveaux P, Frédérick R.
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides, J Med Chem, 2020, 63(9),4628-4643.

Liberelle M, Magnez R, Thuru X, Bencheikh Y, Ravez S, Quenon C, Drucbert AS, Foulon C, Melnyk P, Van Seuningen I, Lebègue N.
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis and Surface Plasmon Resonance, Sci Rep, 2019, 9, 16678-85.