
Laurent L'homme
Publications
Mathilde Lebas, G. Chinigò, Evan Courmont, Louay Bettaieb, Amani Machmouchi, J. Goveia, A. Beatovic, J. van Kerckhove, Cyril Robil, F. S. Angulo, M. Vedelago, A. Errerd, L. Treps, Vance Gao, H. C. Delgado de la Herrán, Alicia Mayeuf-Louchart, Laurent L'Homme, M. Chamlali, C. Dejos, Valerie Gouyer, V. N. S. Garikipati, D. Tomar, H. Yin, H. Fukui, S. Vinckier, A. Stolte, L. C. Conradi, F. Infanti, Loic Lemonnier, E. Zeisberg, Y. Luo, L. Lin, Jean-Luc Desseyn, J. Pickering, R. Kishore, M. Madesh, David Dombrowicz, F. Perocchi, Bart Staels, A. F. Pla, Dimitra Gkika, Anna Rita Cantelmo
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition.
Science Advances , 2024, Sci Adv, 10 (32), eadp6182. ⟨10.1126/sciadv.adp6182⟩
Laurent L’homme, Benan Pelin Sermikli, Joel T Haas, Sébastien Fleury, Sandrine Quemener, Valentine Guinot, Emelie Barreby, Nathalie Esser, Robert Caiazzo, Hélène Verkindt, Benjamin Legendre, Violeta Raverdy, Lydie Cheval, Nicolas Paquot, Jacques Piette, Sylvie Legrand-Poels, Myriam Aouadi, François Pattou, Bart Staels, David Dombrowicz
Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH
Nature Communications, 2024, 15 (1), pp.7173. ⟨10.1038/s41467-024-51078-2⟩
Margaud Iovino, Megan Colonval, Chloé Wilkin, Laurent L’homme, Cédric Lassence, Manon Campas, Olivier Peulen, Pascal de Tullio, Jacques Piette, Sylvie Legrand-Poels
Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid
Frontiers in Immunology, 2023, 14, pp.1204126. ⟨10.3389/fimmu.2023.1204126⟩
Laurent L'Homme, David Dombrowicz
in vitro models of human mast cells: How to get more and better with induced pluripotent stem cells?
Journal of Allergy and Clinical Immunology, 2022, Online ahead of print. ⟨10.1016/j.jaci.2021.12.788⟩
Denis A Mogilenko, Robert Caiazzo, Laurent L'Homme, Laurent Pineau, Violeta Raverdy, Jerome Noulette, Bruno Derudas, Francois Pattou, Bart Staels, David Dombrowicz
IFNγ-producing NK cells in adipose tissue are associated with hyperglycemia and insulin resistance in obese women
International Journal of Obesity, 2021, Online ahead of print. ⟨10.1038/s41366-021-00826-1⟩
Laurent L’homme, Benan Pelin Sermikli, Bart Staels, Jacques Piette, Sylvie Legrand-Poels, David Dombrowicz
Saturated fatty acids promote GDF15 expression in human macrophages through the PERK/eIF2/CHOP signaling pathway
Nutrients, 2020, 12 (12), pp.3771. ⟨10.3390/nu12123771⟩
Laurent L’homme, Benan Pelin Sermikli, Olivier Molendi-Coste, Sébastien Fleury, Sandrine Quemener, Mathilde Le Maître, Marie-Laure Joseph, Laurent Pineau, Christian Duhem, Barbara Gross, Emmanuelle Vallez, Anne Tailleux, Bart Staels, David Dombrowicz
Deletion of the nuclear receptor RORalpha in macrophages does not modify the development of obesity, insulin resistance and NASH
Scientific Reports, 2020, 10 (1), pp.21095. ⟨10.1038/s41598-020-77858-6⟩
Marco A Gianfrancesco, Jonas Dehairs, Laurent l'Homme, Gaëtan Herinckx, Nathalie Esser, Olivia Jansen, Yvette Habraken, Cédric Lassence, Johan V Swinnen, Mark H Rider, Jacques Piette, Nicolas Paquot, Sylvie Legrand-Poels
Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (7), ⟨10.1016/j.bbalip.2019.04.001⟩
Denis Mogilenko, Joel Haas, Laurent L’homme, Sébastien Fleury, Sandrine Quemener, Matthieu Levavasseur, Coralie Becquart, Julien Wartelle, Alexandra Bogomolova, Laurent Pineau, Olivier Molendi-Coste, Steve Lancel, Hélène Dehondt, Celine Gheeraert, Aurelie Melchior, Cédric Dewas, Artemii Nikitin, Samuel Pic, Nabil Rabhi, Jean-Sébastien Annicotte, Seiichi Oyadomari, Talia Velasco-Hernandez, Jörg Cammenga, Marc Foretz, Benoit Viollet, Milica Vukovic, Arnaud Villacreces, Kamil Kranc, Peter Carmeliet, Guillemette Marot, Alexis Boulter, Simon Tavernier, Luciana Berod, Maria Longhi, Christophe Paget, Sophie Janssens, Delphine Staumont-Sallé, Ezra Aksoy, Bart Staels, David Dombrowicz
Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Cell, 2019, 178 (1), pp.263. ⟨10.1016/j.cell.2019.06.017⟩
Denis Mogilenko, Joel Haas, Laurent L’homme, Sébastien Fleury, Sandrine Quemener, Matthieu Levavasseur, Coralie Becquart, Julien Wartelle, Alexandra Bogomolova, Laurent Pineau, Olivier Molendi-Coste, Steve Lancel, Hélène Dehondt, Celine Gheeraert, Aurelie Melchior, Cédric Dewas, Artemii Nikitin, Samuel Pic, Nabil Rabhi, Jean-Sébastien Annicotte, Seiichi Oyadomari, Talia Velasco-Hernandez, Jörg Cammenga, Marc Foretz, Benoit Viollet, Milica Vukovic, Arnaud Villacreces, Kamil Kranc, Peter Carmeliet, Guillemette Marot, Alexis Boulter, Simon Tavernier, Luciana Berod, Maria Longhi, Christophe Paget, Sophie Janssens, Delphine Staumont-Sallé, Ezra Aksoy, Bart Staels, David Dombrowicz
Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Cell, 2019, 178 (1), pp.263. ⟨10.1016/j.cell.2019.06.017⟩
Denis A Mogilenko, Joël Haas, Laurent L'Homme, Sébastien Fleury, Sandrine Quemener, Matthieu Levavasseur, Coralie Becquart, Julien Wartelle, Alexandra Bogomolova, Laurent Pineau, Olivier Molendi-Coste, Steve Lancel, Hélène Dehondt, Céline Gheeraert, Aurélie Melchior, Cédric Dewas, Artemii Nikitin, Samuel Pic, Nabil Rabhi, Jean-Sébastien Annicotte, Seiichi Oyadomari, Talia Velasco-Hernandez, Jörg Cammenga, Marc Foretz, Benoit Viollet, Milica Vukovic, Arnaud Villacreces, Kamil Kranc, Peter Carmeliet, Guillemette Marot, Alexis Boulter, Simon J. Tavernier, Luciana Berod, Maria P. Longhi, Christophe Paget, Sophie Janssens, Delphine Staumont-Sallé, Ezra Aksoy, Bart Staels, David Dombrowicz
Metabolic and innate immune cues merge into a specific inflammatory response via unfolded protein response (UPR)
Cell, In press, 177 (5), pp.1201-1216.e19. ⟨10.1016/j.cell.2019.03.018⟩
Antonio Molinaro, Robert Caesar, Laurent L'Homme, Ara Koh, Marcus Ståhlman, Bart Staels, Fredrik Bäckhed
Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding
Molecular metabolism, 2019, 23, pp.82-87. ⟨10.1016/j.molmet.2019.02.010⟩
Laura Riva, Ok-Ryul Song, Jannick Prentoe, Francois Helle, Laurent L'Homme, Charles-Henry Gattolliat, Alexandre Vandeputte, Lucie Fénéant, Sandrine Belouzard, Thomas F. Baumert, Tarik Asselah, Jens Bukh, Priscille Brodin, Laurence Cocquerel, Yves Rouillé, Jean Dubuisson
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩
Laurent L'Homme, David Dombrowicz
Astrotactin 1–derived peptide: A new skin-penetrating peptide against inflammatory skin diseases
Journal of Allergy and Clinical Immunology, 2017, ⟨10.1016/j.jaci.2017.07.028⟩
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