professeure des universités - InformatiqueCNU : SECTION 27 - INFORMATIQUE
- Laboratoire / équipe
- Composantes, facultés
Domaines de recherche
Recherche opérationnelle, optimisation combinatoire, optimisation multi-objectif, extraction de connaissances
Actualité / news - 1 postdoc position proposal
Approches biclustering sur une représentation de type « embedding » pour mieux caractériser les endotypes de maladies inflammatoires chroniques
Applications are invited for a 2-year postdoctoral fellow to begin on January 1, 2021.
The position will be co-supervised by Pr. Clarisse Dhaenens, computer Science, Pr. Vincent Sobanski, internal medicine and Pr. Grégoire Ficheur, medical informatics.
The applicant should have a PhD in Computer Science. The ideal candidate would have expertise in one or more of the following areas:
Operations research, Combinatorial Optimization, Data Mining (clustering, bi-clustering), optimization approaches, textual analysis…
An interest or an experience about health domain will be appreciated.
The position is open to candidates of any nationality and selection will be based upon the candidate's research record and potential.
Application material will be submitted by e-mail to email@example.com before December 1st 2020, and include (in a single PDF file)
- Cover letter
- 2 reference letters
- Research statement
The objective of this project is to use a biclustering approach to combine two different and complementary data sources in order to better characterize endotypes of chronic inflammatory diseases:
• Build a "word embedding" type representation based on BERT modeling (Bidirectional Encoder Representations from Transformers, Devlin 2018) from textual concepts present in medical letters from a computerized patient records database
• Filter a set of characteristics unrelated to the type of diagnosis that may be found among the interests of patients
• Build clusters by the biclustering method, based on (i) the identified signs, (ii) on the previously constructed embedding and / or (iii) on the variables from a local complete database
• Compare the clusters obtained using these different approaches, in particular with regard to the concordance on the grouping of patients as well as on the clinical relevance of the subgroups identified.
She/He will also work actively with the INCLUDE team at the Lille University Hospital
(health data warehouse project - https://include-project.chru-lille.fr/en/the-team/https://include-project.chru-lille.fr/en/the-team/),
the METRICS team (ULR 2694, Lille University Hospital),
and the INFINITE team (INSERM U1286, Lille University Hospital - http://lille-inflammation-research.org/en/workpackages/861-wp3-enhttp://lille-inflammation-research.org/en/workpackages/861-wp3-en).
Do not hesitate to contact us to have more details.
A complete description of the projet can be sent if required.