Dominique Legrand
Directeur de recherche epst
Laboratoire / équipe
Publications
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"citationFull_s":"Gargouch Nesrine, Mélissandre Herbaut, Dominique Legrand, Vianney Deleplace, Sylvain Julien, et al.. TMEM165, a new molecular actor involved in the regulation of the N-glycosylation of the marine microalgae Phaeodactylum tricornutum. <i>29 ème Journées du Groupe Français des Glycosciences</i>, May 2024, Obernai, France. <a target=\"_blank\" href=\"https://normandie-univ.hal.science/hal-04617847v1\">⟨hal-04617847⟩</a>",
"title_s":["TMEM165, a new molecular actor involved in the regulation of the N-glycosylation of the marine microalgae Phaeodactylum tricornutum"],
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"citationRef_s":"<i>FEBS Open Bio</i>, 2023, 13, pp.249. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/2211-5463.13646\">⟨10.1002/2211-5463.13646⟩</a>",
"citationFull_s":"Dominique Legrand, Mélissandre Herbaut, Zoé Durin, Guillaume Brysbaert, Marc F Lensink, et al.. Solving the pathogenecity of TMEM16 variants using structural modeling based on AlphaFold 2 predictions. <i>FEBS Open Bio</i>, 2023, 13, pp.249. <a target=\"_blank\" href=\"https://dx.doi.org/10.1002/2211-5463.13646\">⟨10.1002/2211-5463.13646⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-04235441v1\">⟨hal-04235441⟩</a>",
"title_s":["Solving the pathogenecity of TMEM16 variants using structural modeling based on AlphaFold 2 predictions"],
"authFullName_s":["Dominique Legrand","Mélissandre Herbaut","Zoé Durin","Guillaume Brysbaert","Marc F Lensink","François Foulquier"],
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"citationRef_s":"<i>Computational and Structural Biotechnology Journal</i>, 2023, 21, pp.3424-3436. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.csbj.2023.06.015\">⟨10.1016/j.csbj.2023.06.015⟩</a>",
"citationFull_s":"Dominique Legrand, Mélissandre Herbaut, Zoé Durin, Guillaume Brysbaert, Muriel Bardor, et al.. New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions. <i>Computational and Structural Biotechnology Journal</i>, 2023, 21, pp.3424-3436. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.csbj.2023.06.015\">⟨10.1016/j.csbj.2023.06.015⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-04141374v1\">⟨hal-04141374⟩</a>",
"title_s":["New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions"],
"authFullName_s":["Dominique Legrand","Mélissandre Herbaut","Zoé Durin","Guillaume Brysbaert","Muriel Bardor","Marc F Lensink","François Foulquier"],
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"citationRef_s":"<i>Human Genetics</i>, 2022, 141 (7), pp.1287-1298. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s00439-021-02420-x\">⟨10.1007/s00439-021-02420-x⟩</a>",
"citationFull_s":"Zoe Durin, Johanne Dubail, Aurore Layotte, Dominique Legrand, Valérie Cormier-Daire, et al.. SLC10A7, an orphan member of the SLC10 family involved in congenital disorders of glycosylation. <i>Human Genetics</i>, 2022, 141 (7), pp.1287-1298. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s00439-021-02420-x\">⟨10.1007/s00439-021-02420-x⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03538979v1\">⟨hal-03538979⟩</a>",
"title_s":["SLC10A7, an orphan member of the SLC10 family involved in congenital disorders of glycosylation"],
"authFullName_s":["Zoe Durin","Johanne Dubail","Aurore Layotte","Dominique Legrand","Valérie Cormier-Daire","Francois Foulquier"],
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"citationRef_s":"<i>Biochimica et Biophysica Acta (BBA) - General Subjects</i>, 2020, 1864 (10), pp.129674. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bbagen.2020.129674\">⟨10.1016/j.bbagen.2020.129674⟩</a>",
"citationFull_s":"François Foulquier, Dominique Legrand. Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis. <i>Biochimica et Biophysica Acta (BBA) - General Subjects</i>, 2020, 1864 (10), pp.129674. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.bbagen.2020.129674\">⟨10.1016/j.bbagen.2020.129674⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02997375v1\">⟨hal-02997375⟩</a>",
"title_s":["Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis"],
"authFullName_s":["François Foulquier","Dominique Legrand"],
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"citationRef_s":"<i>Biochimie</i>, 2019, 165, pp.123-130. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.biochi.2019.07.016\">⟨10.1016/j.biochi.2019.07.016⟩</a>",
"citationFull_s":"Elodie Lebredonchel, Marine Houdou, Sven Potelle, Geoffroy de Bettignies, Céline Schulz, et al.. Dissection of TMEM165 function in Golgi glycosylation and its Mn2+ sensitivity. <i>Biochimie</i>, 2019, 165, pp.123-130. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.biochi.2019.07.016\">⟨10.1016/j.biochi.2019.07.016⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02390802v1\">⟨hal-02390802⟩</a>",
"title_s":["Dissection of TMEM165 function in Golgi glycosylation and its Mn2+ sensitivity"],
"authFullName_s":["Elodie Lebredonchel","Marine Houdou","Sven Potelle","Geoffroy de Bettignies","Céline Schulz","Marie-Ange Krzewinski Recchi","Vladimir Lupashin","Dominique Legrand","André Klein","François Foulquier"],
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"citationRef_s":"<i>Transfusion Clinique et Biologique</i>, 2019, 26 (3), pp.S95. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.tracli.2019.06.204\">⟨10.1016/j.tracli.2019.06.204⟩</a>",
"citationFull_s":"Elyès Ben Khalifa, Maelle Detoc, Alain Lefebvre, Julie Huet, Sophie Titoulet, et al.. Inflammation et écologie du stress en application au don de sang : expérience au sein de l’EFS Auvergne–Rhône-Alpes (Saint-Étienne). <i>Transfusion Clinique et Biologique</i>, 2019, 26 (3), pp.S95. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.tracli.2019.06.204\">⟨10.1016/j.tracli.2019.06.204⟩</a>. <a target=\"_blank\" href=\"https://shs.hal.science/halshs-02613721v1\">⟨halshs-02613721⟩</a>",
"title_s":["Inflammation et écologie du stress en application au don de sang : expérience au sein de l’EFS Auvergne–Rhône-Alpes (Saint-Étienne)"],
"authFullName_s":["Elyès Ben Khalifa","Maelle Detoc","Alain Lefebvre","Julie Huet","Sophie Titoulet","Dominique Legrand","Fabrice Cognasse","Pascal Vallet"],
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"citationRef_s":"<i>FASEB Journal</i>, 2019, 33 (2), pp.2669-2679. <a target=\"_blank\" href=\"https://dx.doi.org/10.1096/fj.201800387R\">⟨10.1096/fj.201800387R⟩</a>",
"citationFull_s":"Marine Houdou, Elodie Lebredonchel, Anne Garat, Sandrine Duvet, Dominique Legrand, et al.. Involvement of thapsigargin– and cyclopiazonic acid–sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn 2+. <i>FASEB Journal</i>, 2019, 33 (2), pp.2669-2679. <a target=\"_blank\" href=\"https://dx.doi.org/10.1096/fj.201800387R\">⟨10.1096/fj.201800387R⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-02390809v1\">⟨hal-02390809⟩</a>",
"title_s":["Involvement of thapsigargin– and cyclopiazonic acid–sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn 2+"],
"authFullName_s":["Marine Houdou","Elodie Lebredonchel","Anne Garat","Sandrine Duvet","Dominique Legrand","Valérie Decool","André Klein","Mohamed Ouzzine","Bruno Gasnier","Sven Potelle","François Foulquier"],
"halId_s":"hal-02390809",
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"producedDateY_i":2019
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"citationRef_s":"<i>Nanoscale</i>, 2014, Nanoscale, 6 (13), pp.7379-7390. <a target=\"_blank\" href=\"https://dx.doi.org/10.1039/c4nr01110d\">⟨10.1039/c4nr01110d⟩</a>",
"citationFull_s":"Nadia Skandrani, Alexandre Barras, Dominique Legrand, Tijani Gharbi, Hatem Boulahdour, et al.. Lipid nanocapsules functionalized with polyethyleneimine for plasmid DNA and drug co-delivery and cell imaging. <i>Nanoscale</i>, 2014, Nanoscale, 6 (13), pp.7379-7390. <a target=\"_blank\" href=\"https://dx.doi.org/10.1039/c4nr01110d\">⟨10.1039/c4nr01110d⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03174734v1\">⟨hal-03174734⟩</a>",
"title_s":["Lipid nanocapsules functionalized with polyethyleneimine for plasmid DNA and drug co-delivery and cell imaging"],
"authFullName_s":["Nadia Skandrani","Alexandre Barras","Dominique Legrand","Tijani Gharbi","Hatem Boulahdour","Rabah Boukherroub"],
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"citationRef_s":"<i>Human Molecular Genetics</i>, 2013, Human Molecular Genetics, 22 (14), pp.2914-2928. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/hmg/ddt146\">⟨10.1093/hmg/ddt146⟩</a>",
"citationFull_s":"Claire Rosnoblet, Dominique Legrand, Didier Demaegd, Hêla Hacine-Gherbi, Geoffroy de Bettignies, et al.. Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II. <i>Human Molecular Genetics</i>, 2013, Human Molecular Genetics, 22 (14), pp.2914-2928. <a target=\"_blank\" href=\"https://dx.doi.org/10.1093/hmg/ddt146\">⟨10.1093/hmg/ddt146⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03159619v1\">⟨hal-03159619⟩</a>",
"title_s":["Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II"],
"authFullName_s":["Claire Rosnoblet","Dominique Legrand","Didier Demaegd","Hêla Hacine-Gherbi","Geoffroy de Bettignies","Riet Bammens","Cindy Borrego","Sandrine Duvet","Pierre Morsomme","Gert Matthijs","Francois Foulquier"],
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"citationRef_s":"<i>Proceedings of the National Academy of Sciences of the United States of America</i>, 2013, Proceedings of the National Academy of Sciences of the United States of America, 110 (17), pp.6859-6864. <a target=\"_blank\" href=\"https://dx.doi.org/10.1073/pnas.1219871110\">⟨10.1073/pnas.1219871110⟩</a>",
"citationFull_s":"Didier Demaegd, Francois Foulquier, Anne-Sophie Colinet, Louis Gremillon, Dominique Legrand, et al.. Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells. <i>Proceedings of the National Academy of Sciences of the United States of America</i>, 2013, Proceedings of the National Academy of Sciences of the United States of America, 110 (17), pp.6859-6864. <a target=\"_blank\" href=\"https://dx.doi.org/10.1073/pnas.1219871110\">⟨10.1073/pnas.1219871110⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03159522v1\">⟨hal-03159522⟩</a>",
"title_s":["Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells"],
"authFullName_s":["Didier Demaegd","Francois Foulquier","Anne-Sophie Colinet","Louis Gremillon","Dominique Legrand","Pascal Mariot","Edgar Peiter","Emile van Schaftingen","Gert Matthijs","Pierre Morsomme"],
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"citationRef_s":"<i>Glycoconjugate Journal</i>, 2013, Glycoconjugate journal, 30 (1), pp.23-31. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s10719-012-9389-y\">⟨10.1007/s10719-012-9389-y⟩</a>",
"citationFull_s":"Claire Rosnoblet, Romain Péanne, Dominique Legrand, Francois Foulquier. Glycosylation disorders of membrane trafficking. <i>Glycoconjugate Journal</i>, 2013, Glycoconjugate journal, 30 (1), pp.23-31. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s10719-012-9389-y\">⟨10.1007/s10719-012-9389-y⟩</a>. <a target=\"_blank\" href=\"https://hal.univ-lille.fr/hal-03158962v1\">⟨hal-03158962⟩</a>",
"title_s":["Glycosylation disorders of membrane trafficking"],
"authFullName_s":["Claire Rosnoblet","Romain Péanne","Dominique Legrand","Francois Foulquier"],
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"citationRef_s":"<i>Journal of Biological Chemistry</i>, 2012, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1074/jbc.M112.392209\">⟨10.1074/jbc.M112.392209⟩</a>",
"citationFull_s":"Claire Rosnoblet, Bernd Fritzinger, Dominique Legrand, Hélène Launay, Jean-Michel Wieruszeski, et al.. Hepatitis C Virus NS5B and Host Cyclophilin A share a common binding site on NS5A.. <i>Journal of Biological Chemistry</i>, 2012, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1074/jbc.M112.392209\">⟨10.1074/jbc.M112.392209⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00765873v1\">⟨hal-00765873⟩</a>",
"title_s":["Hepatitis C Virus NS5B and Host Cyclophilin A share a common binding site on NS5A."],
"authFullName_s":["Claire Rosnoblet","Bernd Fritzinger","Dominique Legrand","Hélène Launay","Jean-Michel Wieruszeski","Guy Lippens","Xavier Hanoulle"],
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"citationRef_s":"<i>FEBS Journal</i>, 2011, 278 (14), pp.2552-2564. <a target=\"_blank\" href=\"https://dx.doi.org/10.1111/j.1742-4658.2011.08180.x\">⟨10.1111/j.1742-4658.2011.08180.x⟩</a>",
"citationFull_s":"Marie-Estelle Losfels, Arnaud Leroy, Bernadette Coddeville, Mathieu Carpentier, Joel Mazurier, et al.. N-glycosylation influences the structure and self-association abilities of recombinant nucleolin. <i>FEBS Journal</i>, 2011, 278 (14), pp.2552-2564. <a target=\"_blank\" href=\"https://dx.doi.org/10.1111/j.1742-4658.2011.08180.x\">⟨10.1111/j.1742-4658.2011.08180.x⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00641786v1\">⟨hal-00641786⟩</a>",
"title_s":["N-glycosylation influences the structure and self-association abilities of recombinant nucleolin"],
"authFullName_s":["Marie-Estelle Losfels","Arnaud Leroy","Bernadette Coddeville","Mathieu Carpentier","Joel Mazurier","Dominique Legrand"],
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"citationRef_s":"<i>Journal of Biological Chemistry</i>, 2010, 285 (43), pp.33435-33444. <a target=\"_blank\" href=\"https://dx.doi.org/10.1074/jbc.M110.149419\">⟨10.1074/jbc.M110.149419⟩</a>",
"citationFull_s":"Arnaud Leroy, Isabelle Landrieu, Isabelle Huvent, Dominique Legrand, Bernadette Coddeville, et al.. Spectroscopic studies of GSK3β phosphorylation of the neuronal Tau protein and its interaction with the N-terminal domain of apolipoprotein E. <i>Journal of Biological Chemistry</i>, 2010, 285 (43), pp.33435-33444. <a target=\"_blank\" href=\"https://dx.doi.org/10.1074/jbc.M110.149419\">⟨10.1074/jbc.M110.149419⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00641629v1\">⟨hal-00641629⟩</a>",
"title_s":["Spectroscopic studies of GSK3β phosphorylation of the neuronal Tau protein and its interaction with the N-terminal domain of apolipoprotein E"],
"authFullName_s":["Arnaud Leroy","Isabelle Landrieu","Isabelle Huvent","Dominique Legrand","Bernadette Coddeville","Jean-Michel Wieruszeski","Guy Lippens"],
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"citationRef_s":"<i>BioMetals</i>, 2010, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s10534-010-9297-1\">⟨10.1007/s10534-010-9297-1⟩</a>",
"citationFull_s":"Dominique Legrand, Joël Mazurier. A critical review of the roles of host lactoferrin in immunity.. <i>BioMetals</i>, 2010, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1007/s10534-010-9297-1\">⟨10.1007/s10534-010-9297-1⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00469788v1\">⟨hal-00469788⟩</a>",
"title_s":["A critical review of the roles of host lactoferrin in immunity."],
"authFullName_s":["Dominique Legrand","Joël Mazurier"],
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"citationRef_s":"<i>5th International Conference on Microtechnologies in Medicine and Biology, MMB 2009</i>, Apr 2009, Québec, Canada. pp.172-173",
"citationFull_s":"A. Treizebre, Bertrand Bocquet, Dominique Legrand, Joël Mazurier. THz microscopic investigation on living cells. <i>5th International Conference on Microtechnologies in Medicine and Biology, MMB 2009</i>, Apr 2009, Québec, Canada. pp.172-173. <a target=\"_blank\" href=\"https://hal.science/hal-00474108v1\">⟨hal-00474108⟩</a>",
"title_s":["THz microscopic investigation on living cells"],
"authFullName_s":["A. Treizebre","Bertrand Bocquet","Dominique Legrand","Joël Mazurier"],
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"citationRef_s":"<i>Médecine/Sciences</i>, 2009, 25 (4), pp.361-9",
"citationFull_s":"Annick Pierce, Dominique Legrand, Joël Mazurier. [Lactoferrin: a multifunctional protein.]. <i>Médecine/Sciences</i>, 2009, 25 (4), pp.361-9. <a target=\"_blank\" href=\"https://hal.science/hal-00385057v1\">⟨hal-00385057⟩</a>",
"title_s":["[Lactoferrin: a multifunctional protein.]"],
"authFullName_s":["Annick Pierce","Dominique Legrand","Joël Mazurier"],
"halId_s":"hal-00385057",
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"citationRef_s":"<i>International Workshop on Optical Terahertz Science and Technology, OTST 2009</i>, Mar 2009, Santa Barbara, CA, United States",
"citationFull_s":"A. Treizebre, Dominique Legrand, Joël Mazurier, Bertrand Bocquet. THz microscopic investigation for molecular and cellular biology. <i>International Workshop on Optical Terahertz Science and Technology, OTST 2009</i>, Mar 2009, Santa Barbara, CA, United States. <a target=\"_blank\" href=\"https://hal.science/hal-00575738v1\">⟨hal-00575738⟩</a>",
"title_s":["THz microscopic investigation for molecular and cellular biology"],
"authFullName_s":["A. Treizebre","Dominique Legrand","Joël Mazurier","Bertrand Bocquet"],
"halId_s":"hal-00575738",
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"citationRef_s":"<i>Experimental Cell Research</i>, 2008, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.yexcr.2008.10.039\">⟨10.1016/j.yexcr.2008.10.039⟩</a>",
"citationFull_s":"Marie-Estelle Losfeld, Diala El Khoury, Pascal Mariot, Mathieu Carpentier, Bernard Krust, et al.. The cell surface expressed nucleolin is a glycoprotein that triggers calcium entry into mammalian cells.. <i>Experimental Cell Research</i>, 2008, epub ahead of print. <a target=\"_blank\" href=\"https://dx.doi.org/10.1016/j.yexcr.2008.10.039\">⟨10.1016/j.yexcr.2008.10.039⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00347895v1\">⟨hal-00347895⟩</a>",
"title_s":["The cell surface expressed nucleolin is a glycoprotein that triggers calcium entry into mammalian cells."],
"authFullName_s":["Marie-Estelle Losfeld","Diala El Khoury","Pascal Mariot","Mathieu Carpentier","Bernard Krust","Jean-Paul Briand","Joël Mazurier","Ara G Hovanessian","Dominique Legrand"],
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"citationRef_s":"<i>Joint 33rd International Conference on Infrared and Millimeter Waves and 16th International Conference on Terahertz Electronics, IRMMW-THz 2008</i>, Sep 2008, Pasadena, CA, United States. pp.1-2, <a target=\"_blank\" href=\"https://dx.doi.org/10.1109/ICIMW.2008.4665843\">⟨10.1109/ICIMW.2008.4665843⟩</a>",
"citationFull_s":"A. Treizebre, Bertrand Bocquet, Dominique Legrand, Joël Mazurier. Studies of cellular informative transfer by THz BioMEMS. <i>Joint 33rd International Conference on Infrared and Millimeter Waves and 16th International Conference on Terahertz Electronics, IRMMW-THz 2008</i>, Sep 2008, Pasadena, CA, United States. pp.1-2, <a target=\"_blank\" href=\"https://dx.doi.org/10.1109/ICIMW.2008.4665843\">⟨10.1109/ICIMW.2008.4665843⟩</a>. <a target=\"_blank\" href=\"https://hal.science/hal-00362354v1\">⟨hal-00362354⟩</a>",
"title_s":["Studies of cellular informative transfer by THz BioMEMS"],
"authFullName_s":["A. Treizebre","Bertrand Bocquet","Dominique Legrand","Joël Mazurier"],
"halId_s":"hal-00362354",
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"producedDateY_i":2008
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"citationRef_s":"<i>Physiological Measurement</i>, 2008, 29 (6), pp.S213-S225. <a target=\"_blank\" href=\"https://dx.doi.org/10.1088/0967-3334/29/6/S19\">⟨10.1088/0967-3334/29/6/S19⟩</a>",
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