David Launay

Professeur des universités-praticien hospitalier - Médecine Interne et Immunologie Clinique
CNU : SECTION 5301 - MEDECINE INTERNE
david_launay.jpeg

David Launay

Professeur des universités-praticien hospitalier - Médecine Interne et Immunologie Clinique

Publications

Article dans une revue scientifique

Major Publications

Before 2009, date of my PhD, I published 73 manuscripts and 218 after my PhD for a total of 291 manuscripts including 226  articles, 32 reviews, 22 letters and 11 editorials. Thirty three manuscripts are in the top10% InCites and 3 in the top 1%. My works were cited 6727 times with h-index of 42.

Among these publications, I will present the following 10 ones (* means that both authors contributed equally), which are linked to the present project and pave the way for the next disrupting stage of my work.

First, I show that SSc was a very severe disease even in the modern era by conducting a national study (Pokeerbux MR, Giovannelli J, Dauchet L, Mouthon L, Agard C, Lega JC, Allanore Y, Jego P, Bienvenu B, Berthier S, Mekinian A, Hachulla E, Launay D. Survival and prognosis factors in systemic sclerosis: data of a French multicenter cohort, systematic review, and meta-analysis of the literature. Arthritis Res Ther. 2019 Apr 3;21(1):86. doi: 10.1186/s13075-019-1867-1. PMID: 30944015; PMCID: PMC6446383), cited 18 times (top10%). Among prognosis factors, positivity for antiTOPO1 was associated with a significant higher risk of death. This study completed a previous one which I initiated, conducted and supervised on the prognosis of SSc patients with pulmonary hypertension (Lefèvre G, Dauchet L, Hachulla E, Montani D, Sobanski V, Lambert M, Hatron PY, Humbert M, Launay D. Survival and prognostic factors in systemic sclerosis-associated pulmonary hypertension: a systematic review and meta-analysis. Arthritis Rheum. 2013 Sep;65(9):2412-23. doi: 10.1002/art.38029. PMID: 23740572). This study has 132 citations (top10%) and was judged by the international scientific community as an important step forward as showed by the title of the accompanying editorial by Hassoun et al. (Tackling the challenges of systemic sclerosis-associated pulmonary hypertension: one step forward. Arthritis Rheum. 2013 Sep;65(9):2240-2). This reinforced the interest I had in understanding the clinical presentation and prognosis of SSc.

Thus, I proposed to EUSTAR a very ambitious and international study aiming to decipher the heterogeneity of SSc by using the large EUSTAR database (>10000 SSc patients) (Sobanski V, Giovannelli J, Allanore Y, Riemekasten G, Airò P, Vettori S, Cozzi F, Distler O, Matucci-Cerinic M, Denton C, Launay D*, Hachulla E; EUSTAR Collaborators. Phenotypes Determined by Cluster Analysis and Their Survival in the Prospective European Scleroderma Trials and Research Cohort of Patients With Systemic Sclerosis. Arthritis Rheumatol. 2019 Sep;71(9):1553-1570. doi: 10.1002/art.40906. Epub 2019 Aug 12. PMID: 30969034; PMCID: PMC6771590.). This study has been cited 20 times (top10%) and is considered as game changing in the understanding of clinical phenotypes of SSc patients, as shown by the accompanying article published in Nature Review Rheumatology analyzing our results (Hinchcliff M, Mahoney JM. Towards a new classification of systemic sclerosis. Nat Rev Rheumatol. 2019 Aug;15(8):456-457. doi: 10.1038/s41584-019-0257-z. PMID: 31217541). In this work, we showed that antiTOPO1 AAb were very important biomarkers of severity and outcome. This reinforced my interest in humoral immunity in SSc. I initiated and supervised a study on the prevalence of another ANA, i.e. antiRNA POLIII AAb, in our cohort of SSc patients completed by the first metaanalysis on this topic (Sobanski V, Dauchet L, Lefèvre G, Lambert M, Morell-Dubois S, Sy T, Hachulla E, Hatron PY, Launay D*, Dubucquoi S. Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: New data from a French cohort and a systematic review and meta-analysis. Arthritis Rheumatol. 2014 Feb;66(2):407-17. doi: 10.1002/art.38219. PMID: 24504813). In this study, we demonstrated that the overall pooled world-wide prevalence of antiRNA POLIII Aab was 11% and highly variable between studies, only partially explained by the geographic factors and not by the variable clinical characteristics of SSc between studies. This study is a reference on this topic with 56 citation (top10%). I completed by initiating and supervising two studies on B cell homeostasis both in human SSc (Forestier A, Guerrier T, Jouvray M, Giovannelli J, Lefèvre G, Sobanski V, Hauspie C, Hachulla E, Hatron PY, Zéphir H, Vermersch P, Labalette M, Launay D*, Dubucquoi S. Altered B lymphocyte homeostasis and functions in systemic sclerosis. Autoimmun Rev. 2018 Mar;17(3):244-255. doi: 10.1016/j.autrev.2017.10.015. Epub 2018 Jan 16. PMID: 29343447; cited 19 times) and a murine model of SSc (Sanges S, Jendoubi M, Kavian N, Hauspie C, Speca S, Crave JC, Guerrier T, Lefèvre G, Sobanski V, Savina A, Hachulla E, Hatron PY, Labalette M, Batteux F, Dubucquoi S, Launay D*. B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis. Front Immunol. 2017 Feb 7;8:53. doi: 10.3389/fimmu.2017.00053. PMID: 28223983; PMCID: PMC5293837; cited twice), showing that animal models could recapitulate the alteration of B cell homeostasis observed in SSc patients. Altogether, these works were important in terms both of scientific impact and to imagine the present project focused on the direct role of ANA in the pathophysiology of SSc. For my PhD, I participated in imaging, building and using an innovative tool to characterize the antigenic targets of ANA, i.e. an optimized fluorescence-based bidimensional immunoproteomic approach (Dutoit-Lefèvre V, Dubucquoi S, Launay D, Sobanski V, Dussart P, Chafey P, Broussard C, Duban-Deweer S, Vermersch P, Prin L, Lefranc D. An Optimized Fluorescence-Based Bidimensional Immunoproteomic Approach for Accurate Screening of Autoantibodies. PLoS One. 2015 Jul 1;10(7):e0132142. doi: 10.1371/journal.pone.0132142. PMID: 26132557; PMCID: PMC4489013, cited 4 times). I fine-tuned this technique to characterize the antigenic targets in neuropsychiatric systemic lupus erythematosus during my PhD (Lefranc D, Launay D*, Dubucquoi S, de Seze J, Dussart P, Vermersch M, Hachulla E, Hatron PY, Vermersch P, Mouthon L, Prin L. Characterization of discriminant human brain antigenic targets in neuropsychiatric systemic lupus erythematosus using an immunoproteomic approach. Arthritis Rheum. 2007 Oct;56(10):3420-32. doi: 10.1002/art.22863. PMID: 17907141, cited 32 times). For the first time, I found that intracellular antigenic targets (MAP-2B and triosephosphate isomerase) in neurons were recognized by immunoglobulins of patients with neuropsychiatric systemic lupus erythematosus.

My aim in understanding the direct role of ANA is to tackle a core and unanswered question, paving the way to find new immunological mechanisms and find new therapeutic options. ANDROID perfectly fits my combined profile of searcher in Immunology and clinician. Indeed, I already participated in several international, game changing randomized control trial as, for example, the role of stem cell transplantation in SSc (van Laar JM, Farge D, Sont JK, Naraghi K, Marjanovic Z, Larghero J, Schuerwegh AJ, Marijt EW, Vonk MC, Schattenberg AV, Matucci-Cerinic M, Voskuyl AE, van de Loosdrecht AA, Daikeler T, Kötter I, Schmalzing M, Martin T, Lioure B, Weiner SM, Kreuter A, Deligny C, Durand JM, Emery P, Machold KP, Sarrot-Reynauld F, Warnatz K, Adoue DF, Constans J, Tony HP, Del Papa N, Fassas A, Himsel A, Launay D, Lo Monaco A, Philippe P, Quéré I, Rich É, Westhovens R, Griffiths B, Saccardi R, van den Hoogen FH, Fibbe WE, Socié G, Gratwohl A, Tyndall A; EBMT/EULAR Scleroderma Study Group. Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial. JAMA. 2014 Jun 25;311(24):2490-8. doi: 10.1001/jama.2014.6368. PMID: 25058083, cited 331 times, top1%), demonstrating for the first time that a treatment was able to increase the survival in this dismal disease. I also coordinated a study at the national level on the role of cyclophosphamide in pulmonary hypertension in autoimmune diseases (Jais X, Launay D*, Yaici A, Le Pavec J, Tchérakian C, Sitbon O, Simonneau G, Humbert M. Immunosuppressive therapy in lupus- and mixed connective tissue disease-associated pulmonary arterial hypertension: a retrospective analysis of twenty-three cases. Arthritis Rheum. 2008 Feb;58(2):521-31. doi: 10.1002/art.23303. PMID: 18240255, cited 204 times, top 10%), which modified the way we treat patients with this condition.

All publications

Pokeerbux MR, Farhat MM, Merger M, Launay D, Hachulla E , Calcinosis in systemic sclerosis.Joint Bone Spine, 2021 , 105180

Scanvion Q, Pascal L, Sy T, Stervinou-Wémeau L, Lejeune AL, Deken V & al , Systemic Pulmonary Events Associated with Myelodysplastic Syndromes: A Retrospective Multicentre Study.J Clin Med, 2021

Belbézier A, Arnaud M, Boccon-Gibod I, Pelletier F, McAvoy C, Gobert D & al , COVID-19 as a trigger of acute attacks in people with hereditary angioedema.Clin Exp Allergy, 2021

Ledoult E, Morelle M, Soussan M, Mékinian A, Béhal H, Sobanski V & al , 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study.Arthritis Res Ther, 2021 , 76

Harb S, Peláez S, Carrier ME, Kwakkenbos L, Bartlett SJ, Hudson M & al , Barriers and facilitators to physical activity for people with scleroderma: a Scleroderma Patient-centered Intervention Network (SPIN) Cohort study.Arthritis Care Res (Hoboken), 2021

Lacoste Palasset T, Chaumais MC, Weatherald J, Savale L, Jaïs X, Price LC & al , Association between Leflunomide and Pulmonary Hypertension.Ann Am Thorac Soc, 2021

Sanges S, Jeanpierre E, Lopez B, Russick J, Delignat S, Carpentier B & al , Acquired Hemophilia A in IgG4-Related Disease: Case Report, Immunopathogenic Study, and Review of the LiteratureFront. Immunol., 2020

Demaret J, Lefèvre G, Vuotto F, Trauet J, Duhamel A, Labreuche J & al , Severe SARS-CoV-2 patients develop a higher specific T-cell response.Clin Transl Immunology, 2020 , e1217

Wu Y, Kwakkenbos L, Henry RS, Carrier ME, Gagarine M, Harb S & al , Factors associated with fears due to COVID-19: A scleroderma patient-centered intervention network (SPIN) COVID-19 cohort study.J Psychosom Res, 2020 , 110314

Billebeau A, Fain O, Launay D, Boccon-Gibod I, Bouillet L, Gobert D & al , Hereditary Angioedema with and Without C1-Inhibitor Deficiency in Postmenopausal Women.J Clin Immunol, 2020

Lhote R, Annesi-Maesano I, Nunes H, Launay D, Borie R, Sacré K & al , Clinical phenotypes of extrapulmonary sarcoidosis: an analysis of a French, multiethnic, multicenter cohort.Eur Respir J, 2020

Thombs BD, Kwakkenbos L, Henry RS, Carrier ME, Patten S, Harb S & al , Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study.J Psychosom Res, 2020 , 110262

Sommer SJ, Harel D, Kwakkenbos L, Carrier ME, Gholizadeh S, Gottesman K & al , Assessing differential item functioning for the Social Appearance Anxiety Scale: a Scleroderma atient-centred Intervention Network (SPIN) Cohort Study.BMJ Open, 2020 , e037639

Blanchet B, Jallouli M, Allard M, Ghillani-Dalbin P, Galicier L, Aumaître O & al , Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence.null, 2020 , 223

Sobanski V, Lescoat A, Launay D , Novel classifications for systemic sclerosis: challenging historical subsets to unlock new doors.Curr Opin Rheumatol, 2020

Chauvelot L, Gamondes D, Berthiller J, Nieves A, Renard S, Catella-Chatron J & al , Hemodynamic response to treatment and outcome in pulmonary hypertension associated with interstitial lung disease versus pulmonary arterial hypertension in systemic sclerosis.null, 2020

Gobert D, Bouillet L, Armengol G, Coppo P, Defendi F, Du-Thanh A & al , [Acquired angioedema due to C1-inhibitor deficiency: CREAK recommendations for diagnosis and treatment].Rev Med Interne, 2020

Leurs A, Dubucquoi S, Machuron F, Balden M, Renaud F, Rogeau S & al , Extended myositis-specific and -associated antibodies profile in systemic sclerosis: a cross-sectional study.Joint Bone Spine, 2020

Sanges S, Farhat MM, Assaraf M, Galland J, Rivière E, Roubille C & al , Raising rare disease awareness using red flags, role play simulation and patient educators: results of a novel educational workshop on Raynaud phenomenon and systemic sclerosis.Orphanet J Rare Dis, 2020 , 159

Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S & al , Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients.J Psychosom Res, 2020 , 110132

Lenfant T, Salah S, Leroux G, Bousquet E, Le Guern V, Chasset F & al , Risk factors for hydroxychloroquine retinopathy in systemic lupus erythematosus: a case-control study with hydroxychloroquine blood-level analysis.Rheumatology (Oxford), 2020 , 3807-3816

Hachulla E, Gouellec NL, Launay D, Balquet MH, Maillard H, Azar R & al , Adherence to hydroxychloroquine in patients with systemic lupus: contrasting results and weak correlation between assessment tools.Joint Bone Spine, 2020

Scanvion Q, Béné J, Gautier S, Grandvuillemin A, Le Beller C, Chenaf C & al , Moderate-to-severe eosinophilia induced by treatment with immune checkpoint inhibitors: 37 cases from a national reference center for hypereosinophilic syndromes and the French pharmacovigilance database.Oncoimmunology, 2020 , 1722022

Forestier A, Le Gouellec N, Béhal H, Kramer G, Perez T, Sobanski V & al , Evolution of high-resolution CT-scan in systemic sclerosis-associated interstitial lung disease: Description and prognosis factors.Semin. Arthritis Rheum., 2020

Kreitmann L, Montaigne D, Launay D, Morell-Dubois S, Maillard H, Lambert M & al , Clinical Characteristics and Outcome of Patients with Infective Endocarditis Diagnosed in a Department of Internal Medicine.J Clin Med, 2020

Bütikofer L, Varisco PA, Distler O, Kowal-Bielecka O, Allanore Y, Riemekasten G & al , ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis-a EUSTAR analysis.Arthritis Res. Ther., 2020 , 59

Chazal T, Varnous S, Guihaire J, Goeminne C, Launay D, Boignard A & al , Sarcoidosis diagnosed on granulomas in the explanted heart after transplantation: Results of a French nationwide study.Int. J. Cardiol., 2020

Marx-Deseure A, Labreuche J, Launay D, Depret S, Subtil D , Are pregnancies with lupus but without APS of good prognosis?Autoimmun Rev, 2020 , 102489

Ledoult E, Launay D, Béhal H, Mouthon L, Pugnet G, Lega JC & al , Early trajectories of skin thickening are associated with severity and mortality in systemic sclerosis.Arthritis Res. Ther., 2020 , 30

Stabler S, Giovannelli J, Launay D, Cotteau-Leroy A, Heusele M, Lefèvre G & al , Serious infectious events and immunoglobulin replacement therapy in patients with autoimmune diseases receiving rituximab: a retrospective cohort study.Clin. Infect. Dis., 2020

Lefèvre G, Leurs A, Gibier JB, Copin MC, Staumont-Sallé D, Dezoteux F & al , \"Idiopathic eosinophilic vasculitis\": another side of hypereosinophilic syndrome? A comprehensive analysis of 117 cases in asthma-free patients.J Allergy Clin Immunol Pract, 2019

Farhat MM, Morell-Dubois S, Le Gouellec N, Launay D, Maillard H, Balquet MH & al , Consideration of coping strategies for patients suffering from systemic lupus erythematosus: reflection for a personalised practice of patient education.Clin. Exp. Rheumatol., 2019

Mihai C, Distler O, Gheorghiu AM, Constantin PI, Dobrota R, Jordan S & al , Incidence and risk factors for gangrene in patients with systemic sclerosis from the EUSTAR cohort.Rheumatology (Oxford), 2019

Hachulla E, Launay D, Boucly A, Mouthon L, de Groote P, Cottin V & al , Survival improved in systemic sclerosis associated pulmonary arterial hypertension patients aged 70 years or less over the period 2006-2017 in France.Chest, 2019

Jaeger VK, Tikly M, Xu D, Siegert E, Hachulla E, Airò P & al , Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study.Rheumatology (Oxford), 2019

Lopez B, Bertier N, Ledoult E, Joudinaud R, Maanaoui M, Majerus V & al , Classical pathway activity C3c, C4 and C1-inhibitor protein reference intervals determination in EDTA plasma.Biochem Med (Zagreb), 2019 , 030707

Kwakkenbos L, Cumin J, Carrier ME, Bartlett SJ, Malcarne VL, Mouthon L & al , Factors associated with patient-reported likelihood of using online self-care interventions: a Scleroderma Patient-centered Intervention Network (SPIN) ohort study.BMJ Open, 2019 , e029542

Ledoult E, Groh M, Kahn JE, Trauet J, Bouaziz JD, Caristan A & al , Assessment of T-cell polarization on the basis of surface marker expression: diagnosis and potential therapeutic implications in lymphocytic variant hypereosinophilic syndrome.J Allergy Clin Immunol Pract, 2019

Bygum A, Caballero T, Grumach AS, Longhurst HJ, Bouillet L, Aberer W & al , Elderly versus younger patients with hereditary angioedema type I/II: patient characteristics and safety analysis from the Icatibant Outcome SurveyClin. Transl. Allergy, 2019

Vigneron C, Lécluse A, Ronzière T, Bouillet L, Boccon-Gibod I, Gayet S & al , Angioedema Associated With Thrombolysis For Ischemic Stroke: Analysis Of A Case-Control Study.J. Intern. Med., 2019

Leurs A, Gnemmi V, Lionet A, Renaud L, Gibier JB, Copin MC & al , Renal Pathologic Findings in TAFRO Syndrome: Is There a Continuum Between Thrombotic Microangiopathy and Membranoproliferative Glomerulonephritis? A Case Report and Literature ReviewFront. Immunol., 2019

Javaud N, Altar A, Fain O, Reuter PG, Desmaizieres M, Petrovic T & al , Hereditary angioedema, emergency management of attacks by a call center.Eur. J. Intern. Med., 2019

Becetti K, Kwakkenbos L, Carrier ME, Gordon JK, Nguyen JT, Mancuso CA & al , Physical or Occupational Therapy Use in Systemic Sclerosis: A Scleroderma Patient-centered Intervention Network Cohort Study.J. Rheumatol., 2019 , 1605-1613

Sobanski V, Giovannelli J, Allanore Y, Riemekasten G, Airò P, Vettori S & al , Phenotypes determined by cluster analysis and their survival in the prospective EUSTAR cohort of patients with systemic sclerosis.null, 2019

Elhai M, Boubaya M, Distler O, Smith V, Matucci-Cerinic M, Alegre Sancho JJ & al , Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study.Ann. Rheum. Dis., 2019

Pokeerbux MR, Giovannelli J, Dauchet L, Mouthon L, Agard C, Lega JC & al , Survival and prognosis factors in systemic sclerosis: data of a French multicenter cohort, systematic review, and meta-analysis of the literature.Arthritis Res. Ther., 2019 , 86

Antunes M, Scirè CA, Talarico R, Alexander T, Avcin T, Belocchi C & al , Undifferentiated connective tissue disease: state of the art on clinical practice guidelines.RMD Open, 2018 , e000786

Meyer A, Scirè CA, Talarico R, Alexander T, Amoura Z, Avcin T & al , Idiopathic inflammatory myopathies: narrative review of unmet needs in clinical practice guidelines.RMD Open, 2018 , e000784

Bonnard G, Cohen-Aubart F, Steichen O, Bourgarit A, Abad S, Ranque B & al , [Reliability and validity of a workbook for assessment of professional competencies of internal medicine residents].Rev Med Interne, 2019

Harel D, Mills SD, Kwakkenbos L, Carrier ME, Nielsen K, Portales A & al , Shortening patient-reported outcome measures through optimal test assembly: application to the Social Appearance Anxiety Scale in the Scleroderma Patient-centered Intervention Network Cohort.BMJ Open, 2019 , e024010

Iaccarino L, Talarico R, Scirè CA, Amoura Z, Burmester G, Doria A & al , IgG4-related diseases: state of the art on clinical practice guidelines.RMD Open, 2018 , e000787

Mahlaoui N, Picard C, Bach P, Costes L, Courteille V, Ranohavimparany A & al , Genetic diagnosis of primary immunodeficiencies: A survey of the French national registry.J. Allergy Clin. Immunol., 2019

Lescoat A, Yelnik CM, Coiffier G, Wargny M, Lamotte C, Cazalets C & al , Ulnar Artery Occlusion and severity markers of vasculopathy in Systemic sclerosis: a multicenter cross-sectional study.null, 2018

Farhat MM, Condette-Wojtasik G, Maillard H, Sobanski V, Lambert M, Launay D & al , [Exploring illness perceptions of lupus patients for a motivational environment in therapeutic education].Rev Med Interne, 2018

Sobanski V, Lemaire-Olivier A, Giovannelli J, Dauchet L, Simon M, Lopez B & al , Prevalence and Clinical Associations of Antiphospholipid Antibodies in Systemic Sclerosis: New Data From a French Cross-Sectional Study, Systematic Review, and Meta-AnalysisFront. Immunol., 2018

Bouillet L, Defendi F, Hardy G, Cesbron JY, Boccon-Gibod I, Deroux A & al , Presse Med, 2018

Titeca-Beauport D, Francois A, Lobbedez T, Guerrot D, Launay D, Vrigneaud L & al , Early predictors of one-year mortality in patients over 65 presenting with ANCA-associated renal vasculitis: a retrospective, multicentre study.BMC Nephrol, 2018 , 317

Champtiaux N, Cottin V, Chassagnon G, Chaigne B, Valeyre D, Nunes H & al , Combined pulmonary fibrosis and emphysema in systemic sclerosis: A syndrome associated with heavy morbidity and mortality.Semin. Arthritis Rheum., 2018

Rednic S, Damian L, Talarico R, Scirè CA, Tobias A, Costedoat-Chalumeau N & al , Relapsing polychondritis: state of the art on clinical practice guidelines.RMD Open, 2018 , e000788

Limper M, Scirè CA, Talarico R, Amoura Z, Avcin T, Basile M & al , Antiphospholipid syndrome: state of the art on clinical practice guidelines.RMD Open, 2018 , e000785

Chaigne B, Scirè CA, Talarico R, Alexander T, Amoura Z, Avcin T & al , Mixed connective tissue disease: state of the art on clinical practice guidelines.RMD Open, 2018 , e000783

Smith V, Scirè CA, Talarico R, Airo P, Alexander T, Allanore Y & al , Systemic sclerosis: state of the art on clinical practice guidelines.RMD Open, 2018 , e000782

Urbanski G, Yelnik CM, Maillard H, Launay D, Dubucquoi S, Hachulla E & al , Antiphospholipid Syndrome With Isolated Isotype M Anticardiolipin and/or Anti-B2GPI Antibody Is Associated With Stroke.Stroke, 2018 , 2770-2772

Leurs A, Chenivesse C, Lopez B, Gibier JB, Clément G, Groh M & al , C-reactive protein as a diagnostic tool in differential diagnosis of hypereosinophilic syndrome and ANCA-negative eosinophilic granulomatosis with polyangiitis.J Allergy Clin Immunol Pract, 2018

Kwakkenbos L, Sanchez TA, Turner KA, Mouthon L, Carrier ME, Hudson M & al , The association of sociodemographic and disease variables with hand function: a Scleroderma Patient-centered Intervention Network cohort study.Clin. Exp. Rheumatol., 2018 , 88-94

Weatherald J, Boucly A, Launay D, Cottin V, Prévot G, Bourlier D & al , Haemodynamics and serial risk assessment in systemic-sclerosis associated pulmonary arterial hypertension.Eur. Respir. J., 2018

Desbois AC, Biard L, Addimanda O, Lambert M, Hachulla E, Launay D & al , Efficacy of anti-TNF alpha in severe and refractory major vessel involvement of Behcet''s disease: A multicenter observational study of 18 patients.Clin. Immunol., 2018

Soudet S, Fajgenbaum D, Delattre C, Forestier A, Hachulla E, Hatron PY & al , Schnitzler syndrome co-occurring with idiopathic multicentric Castleman disease that responds to anti-IL-1 therapy: A case report and clue to pathophysiology.Curr Res Transl Med, 2018

Yelnik CM, Lambert M, Drumez E, Le Guern V, Bacri JL, Guerra MM & al , Bleeding complications and antithrombotic treatment in 264 pregnancies in antiphospholipid syndrome.Lupus, 2018 , 961203318787032

Belbézier A, Hardy G, Marlu R, Defendi F, Dumestre Perard C, Boccon-Gibod I & al , Plasminogen gene mutation with normal C1Inhibitor-hereditary angioedema: Three additional French families.Allergy, 2018

Javaud N, Bouillet L, Rabetrano H, Bitoun A, Launay D, Lapostolle F & al , Hereditary Angioedema, Clinical Presentation and Socio-Economic Cost of 200 French Patients.J Allergy Clin Immunol Pract, 2018

Jouvray M, Launay D, Dubucquoi S, Sobanski V, Podevin C, Lambert M & al , Whole-Body Distribution and Clinical Association of Telangiectases in Systemic Sclerosis.JAMA Dermatol, 2018

Launay D, Montani D, Hassoun PM, Cottin V, Le Pavec J, Clerson P & al , Clinical phenotypes and survival of pre-capillary pulmonary hypertension in systemic sclerosis.PLoS ONE, 2018 , e0197112

Terrier B, Pagnoux C, Perrodeau É, Karras A, Khouatra C, Aumaître O & al , Long-term efficacy of remission-maintenance regimens for ANCA-associated vasculitides.Ann. Rheum. Dis., 2018

Riedl MA, Aygören-Pürsün E, Baker J, Farkas H, Anderson J, Bernstein JA & al , Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: the OPUS-2 study.Allergy, 2018

Thiebaut M, Launay D, Rivière S, Mahévas T, Bellakhal S, Hachulla E & al , Efficacy and safety of rituximab in systemic sclerosis: French retrospective study and literature review.Autoimmun Rev, 2018

Caballero T, Zanichelli A, Aberer W, Maurer M, Longhurst HJ, Bouillet L & al , Effectiveness of icatibant for treatment of hereditary angioedema attacks is not affected by body weight: findings from the Icatibant Outcome Survey, a cohort observational study.Clin Transl Allergy, 2018 , 11

Merz EL, Kwakkenbos L, Carrier ME, Gholizadeh S, Mills SD, Fox RS & al , Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating 'not applicable' responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study.BMJ Open, 2018 , e018641

Javaud N, Fain O, Durand-Zaleski I, Launay D, Bouillet L, Gompel A & al , Specialist Advice Support for Management of Severe Hereditary Angioedema Attacks: A Multicenter Cluster-Randomized Controlled Trial.Ann Emerg Med, 2018

Montani D, Henry J, O''Connell C, Jaïs X, Cottin V, Launay D & al , Association between Rheumatoid Arthritis and Pulmonary Hypertension: Data from the French Pulmonary Hypertension Registry.Respiration, 2018

Leurs A, Launay D, Terriou L, Hatron PY, Quartier P, Hachulla E , Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab.J Clin Rheumatol, 2018

Forestier A, Buob D, Mirault T, Puech P, Gnemmi V, Launay D & al , No specific imaging pattern can help differentiate IgG4-related disease from idiopathic retroperitoneal fibrosis: 18 histologically proven cases.Clin. Exp. Rheumatol., 2018

Fox RS, Kwakkenbos L, Carrier ME, Mills SD, Gholizadeh S, Jewett LR & al , Validation of the Brief Fear of Negative Evaluation Scale-II in patients with systemic sclerosis: A Scleroderma Patient-centered Intervention Network Cohort study.Arthritis Care Res (Hoboken), 2018

Lopez B, Boucher A, Bahuaud M, Mortuaire G, Melliez H, Launay D & al , Polysaccharide Antibody Deficiency: Specific or General? ReplyClin. Infect. Dis., 2018 , 637-638

Forestier A, Guerrier T, Jouvray M, Giovannelli J, Lefèvre G, Sobanski V & al , Altered B lymphocyte homeostasis and functions in systemic sclerosis.Autoimmun Rev, 2018

Mills SD, Kwakkenbos L, Carrier ME, Gholizadeh S, Fox RS, Jewett LR & al , Validation of the Social Appearance Anxiety Scale in Patients with Systemic Sclerosis: A Scleroderma Patient-centered Intervention Network Cohort Study.Arthritis Care Res (Hoboken), 2018

Lopez B, Bahuaud M, Fieschi C, Mehlal S, Jeljeli M, Rogeau S & al , Value of the Overall Pneumococcal Polysaccharide Response in the Diagnosis of Primary Humoral ImmunodeficienciesFront. Immunol., 2017

Guerrier T, Labalette M, Launay D, Lee-Chang C, Outteryck O, Lefèvre G & al , Proinflammatory B-cell profile in the early phases of MS predicts an active disease.Neurol Neuroimmunol Neuroinflamm, 2018 , e431

Sanges S, Giovannelli J, Sobanski V, Morell-Dubois S, Maillard H, Lambert M & al , Factors associated with the 6-minute walk distance in patients with systemic sclerosisArthritis Res. Ther., 2017

Martis N, Queyrel-Moranne V, Launay D, Neviere R, Fuzibet JG, Marquette CH & al , Limited Exercise Capacity in Patients with Systemic Sclerosis: Identifying Contributing Factors with Cardiopulmonary Exercise TestingJ. Rheumatol., 2018 , 95-102

Degano B, Soumagne T, Delaye T, Berger P, Perez T, Guillien A & al , Combined measurement of carbon monoxide and nitric oxide lung transfer does not improve the identification of pulmonary hypertension in systemic sclerosis.Eur. Respir. J., 2017

Louis C, Vijgen S, Samii K, Chalandon Y, Terriou L, Launay D & al , TAFRO Syndrome in Caucasians: A Case Report and Review of the Literature.Front Med (Lausanne), 2017 , 149

Launay D, Sobanski V, Hachulla E, Humbert M , Pulmonary hypertension in systemic sclerosis: different phenotypes.Eur Respir Rev, 2017

INGEGNOLI F, UGHI N, DINSDALE G, ORENTI A, BORACCHI P, ALLANORE Y & al , An international SUrvey on non-iNvaSive tecHniques to assess the mIcrocirculation in patients with RayNaud's phEnomenon (SUNSHINE survey).Rheumatol. Int., 2017 , 1879-1890

Hachulla E, Jais X, Cinquetti G, Clerson P, Rottat L, Launay D & al , Pulmonary Arterial Hypertension Associated With Systemic Lupus Erythematosus Results From the French Pulmonary Hypertension RegistryChest, 2018 , 143-151

Avouac J, Guignabert C, Hoffmann-Vold AM, Ruiz B, Dorfmuller P, Pezet S & al , Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic SclerosisArthritis Rheumatol., 2017 , 2209-2221

Le Gouellec N, Duhamel A, Perez T, Hachulla AL, Sobanski V, Faivre JB & al , Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung diseasePLoS One, 2017

Yelnik CM, Urbanski G, Drumez E, Caron C, Maillard H, Morell-Dubois S & al , Anticoagulation withdrawal in antiphospholipid syndrome: a retrospective matched-control studyLupus, 2018 , 357-364

Andre R, Cottin V, Saraux JL, Blaison G, Bienvenu B, Cathebras P & al , Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literatureAutoimmun. Rev., 2017 , 963-969

Mekinian A, Dervin G, Lapidus N, Kahn JE, Terriou L, Liozon E & al , Biologics in myelodysplastic syndrome-related systemic inflammatory and autoimmune diseases: French multicenter retrospective study of 29 patientsAutoimmun. Rev., 2017 , 903-910

Peres N, Morell-Dubois S, Hachulla E, Hatron PY, Duhamel A, Godard D & al , Systemic sclerosis and occupational difficulties: Results of a prospective studyRev. Med. Interne, 2017 , 718-724

Aberer W, Maurer M, Bouillet L, Zanichelli A, Caballero T, Longhurst HJ & al , Breakthrough attacks in patients with hereditary angioedema receiving long-term prophylaxis are responsive to icatibant: findings from the Icatibant Outcome Survey.Allergy Asthma Clin Immunol, 2017 , 31

Launay D, Sobanski V , [Pulmonary hypertension screening in systemic sclerosis: The best strategy remains to be defined].Rev Med Interne, 2017 , 499-501

Sanges S, Prévotat A, Fertin M, Terriou L, Lefèvre G, Quesnel B & al , Haemodynamically proven pulmonary hypertension in a patient with GATA2 deficiency-associated pulmonary alveolar proteinosis and fibrosis.Eur. Respir. J., 2017

Desvignes C, Becquart C, Launay D, Terriou L, Patenotre P, Deheul S & al , Extensive levamisole-induced vasculitisClin. Exp. Dermatol., 2017 , 413-415

Lopez B, Boucher A, Bahuaud M, Mortuaire G, Melliez H, Launay D & al , Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 CasesClin. Infect. Dis., 2017 , 328-331

Caballero T, Aberer W, Longhurst HJ, Maurer M, Zanichelli A, Perrin A & al , The Icatibant Outcome Survey: experience of hereditary angioedema management from six European countries.J Eur Acad Dermatol Venereol, 2017 , 1214-1222

Rosain J, Hong E, Fieschi C, Vieira Martins P, El Sissy C, Deghmane AE & al , Strains Responsible for Invasive Meningococcal Disease in Patients With Terminal Complement Pathway DeficienciesJ. Infect. Dis., 2017 , 1331-1338

Marlu R, Deroux A, Du-Thanh A, Boccon-Gibod I, Launay D, Bouillet L , Normal PAI-2 level in French FXII-HAE patientsJ. Allergy Clin. Immunol., 2017 , 1719-1720

Adens A, Landy P, Terriou L, Baillet C, Beron A, Lambert M & al , Usefulness of nuclear medicine in Erdheim-Chester disease: A Lille experienceRev. Med. Interne, 2017 , 235-242

Bouillet L, Boccon-Gibod I, Gompel A, Floccard B, Martin L, Blanchard-Delaunay C & al , Hereditary angioedema with normal C1 inhibitor: clinical characteristics and treatment response with plasma-derived human C1 inhibitor concentrate (Berinert (R)) in a French cohortEur. J. Dermatol., 2017 , 155-159

Bouillet L, Boccon-Gibod I, Launay D, Gompel A, Kanny G, Fabien V & al , Hereditary angioedema with normal C1 inhibitor in a French cohort: Clinical characteristics and response to treatment with icatibant.Immun Inflamm Dis, 2017 , 29-36

Sanges S, Rivière S, Mekinian A, Martin T, Le Quellec A, Chatelus E & al , Intravenous immunoglobulins in systemic sclerosis: Data from a French nationwide cohort of 46 patients and review of the literatureAutoimmun. Rev., 2017 , 377-384

Sanges S, Jendoubi M, Kavian N, Hauspie C, Speca S, Crave JC & al , B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic SclerosisFront. Immunol., 2017

Sanges S, Wallet F, Blondiaux N, Theis D, Verin I, Vachee A & al , Diagnosis of primary antibody and complement deficiencies in young adults after a first invasive bacterial infectionClin. Microbiol. Infect., 2017

Floccard B, Javaud N, Deroux A, Boccon-Gibod I, Fain O, Amarger S & al , Diagnosis and treatment of upper airway oedema caused by acute angio-oedema in the emergency department: a French consensus statementEur. J. Emerg. Med., 2017 , 318-325

Caballero T, Maurer M, Longhurst HJ, Aberer W, Bouillet L, Fabien V , Triggers and Prodromal Symptoms of Angioedema Attacks in Patients With Hereditary Angioedema.J Investig Allergol Clin Immunol, 2016 , 383-386

Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y & al , Update of EULAR recommendations for the treatment of systemic sclerosis.Ann. Rheum. Dis., 2017 , 1327-1339

Zanichelli A, Maurer M, Aberer W, Caballero T, Longhurst HJ, Bouillet L & al , Long-term safety of icatibant treatment of patients with angioedema in real-world clinical practice.Allergy, 2017 , 994-998

Zanichelli A, Longhurst HJ, Maurer M, Bouillet L, Aberer W, Fabien V & al , Misdiagnosis trends in patients with hereditary angioedema from the real-world clinical setting.Ann. Allergy Asthma Immunol., 2016 , 394-398

Chater C, Terriou L, Duhamel A, Launay D, Chambon JP, Pruvot FR & al , Reemergence of Splenectomy for ITP Second-line Treatment?Ann. Surg., 2016 , 772-777

Sanges S, Yelnik CM, Sitbon O, Benveniste O, Mariampillai K, Phillips-Houlbracq M & al , Pulmonary arterial hypertension in idiopathic inflammatory myopathies: Data from the French pulmonary hypertension registry and review of the literatureMedicine (Baltimore), 2016

Launay D , A New Era in the Treatment of Scleroderma-associated Interstitial Lung Disease?J. Rheumatol., 2016 , 1619-1621

Allanore Y, Komocsi A, Vettori S, Hachulla E, Hunzelmann N, Distler J & al , N-terminal pro-brain natriuretic peptide is a strong predictor of mortality in systemic sclerosisInt. J. Cardiol., 2016 , 385-389

Gobert D, Paule R, Ponard D, Levy P, Frémeaux-Bacchi V, Bouillet L & al , A nationwide study of acquired C1-inhibitor deficiency in France Characteristics and treatment responses in 92 patientsMedicine (Baltimore), 2016

Ghrenassia E, Mekinian A, Chapelon-Albric C, Levy P, Cosnes J, Sève P & al , Digestive-tract sarcoidosis French nationwide case-control study of 25 casesMedicine (Baltimore), 2016

Yelnik CM, Urbanski G, Drumez E, Sobanski V, Maillard H, Lanteri A & al , Persistent triple antiphospholipid antibody positivity as a strong risk factor of first thrombosis, in a long-term follow-up study of patients without history of thrombosis or obstetrical morbidityLupus, 2017 , 163-169

Sanges S, Desauw C, de Groote P, Fertin M, Lamblin N, Bervar JF & al , Tolerance of bevacizumab therapy in systemic sclerosis-associated pulmonary arterial hypertension: A case reportRev. Med. Interne, 2017 , 274-277

Chandesris MO, Damaj G, Canioni D, Brouzes C, Lhermitte L, Hanssens K & al , Midostaurin in Advanced Systemic MastocytosisN. Engl. J. Med., 2016 , 2605-2607

Rouet A, Aouba A, Damaj G, Soucié E, Hanssens K, Chandesris MO & al , y Mastocytosis among elderly patients A multicenter retrospective French study on 53 patientsMedicine (Baltimore), 2016

Desbois AC, Addimanda O, Bertrand A, Deroux A, Pérard L, Depaz R & al , Efficacy of Anti-TNF alpha in Severe and Refractory Neuro-Behcet Disease An Observational StudyMedicine (Baltimore), 2016

Deroux A, Boccon-Gibod I, Fain O, Pralong P, Ollivier Y, Pagnier A & al , Hereditary angioedema with normal C1 inhibitor and factor XII mutation: a series of 57 patients from the French National Center of Reference for AngioedemaClin. Exp. Immunol., 2016 , 332-337

Sobanski V, Launay D, Depret S, Ducloy-Bouthors AS, Hachulla E , Special considerations in pregnant systemic sclerosis patientsExpert Rev. Clin. Immunol., 2016 , 1161-1173

Javaud N, Fain O, Durand-Zaleski I, Launay D, Bouillet L, Gompel A & al , Dedicated call center (SOS-HAE) for hereditary angioedema attacks: study protocol for a randomised controlled trialTrials, 2016

Anquetil C, Stavris C, Chanson N, Lambert M, Hachulla E, Launay D & al , Hemorrhagic shock revealing multiple digestive microaneurysms in a patient with systemic lupus erythematosus: Case report and literature reviewRev. Med. Interne, 2017 , 56-60

Sanges S, Guerrier T, Launay D, Lefèvre G, Labalette M, Forestier A & al , Role of B cells in the pathogenesis of systemic sclerosisRev. Med. Interne, 2017 , 113-124

Dobrota R, Maurer B, Graf N, Jordan S, Mihai C, Kowal-Bielecka O & al , Prediction of improvement in skin fibrosis in diffuse cutaneous systemic sclerosis: a EUSTAR analysis.Ann. Rheum. Dis., 2016 , 1743-8

de Boysson H, Martin Silva N, de Moreuil C, Néel A, de Menthon M, Meyer O & al , Neutrophilic Dermatoses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis A French Multicenter Study of 17 Cases and Literature ReviewMedicine (Baltimore), 2016

Sobanski V, Launay D, Hachulla E, Humbert M , Current Approaches to the Treatment of Systemic-Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)Curr. Rheumatol. Rep., 2016

Georgin-Lavialle S, Moura DS, Salvador A, Chauvet-Gelinier JC, Launay JM, Damaj G & al , Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis.Mol. Psychiatry, 2016 , 1511-1516

Allenbach Y, Leroux G, Suárez-Calvet X, Preusse C, Gallardo E, Hervier B & al , Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.Am. J. Pathol., 2016 , 691-700

Kreitmann L, Terriou L, Launay D, Caspar Y, Courcol R, Maurin M & al , Disseminated Infection Caused by Francisella philomiragia, France, 2014Emerg. Infect. Dis, 2015 , 2260-2261

Puéchal X, Pagnoux C, Perrodeau É, Hamidou M, Boffa JJ, Kyndt X & al , Long-Term Outcomes Among Participants in the WEGENT Trial of Remission-Maintenance Therapy for Granulomatosis With Polyangiitis (Wegener's) or Microscopic PolyangiitisArthritis Rheumatol., 2016 , 690-701

Carvalhosa AB, Aouba A, Damaj G, Canioni D, Brouzes C, Gyan E & al , A French National Survey on Clotting Disorders in MastocytosisMedicine (Baltimore), 2015

Jouvray M, Terriou L, Meignin V, Bouchindhomme B, Jourdain M, Lambert M & al , Pseudo-adult Still's disease, anasarca, thrombotic thrombocytopenic purpura and dysautonomia: An atypical presentation of multicentric Castleman's disease. Discussion of TAFRO syndromeRev. Med. Interne, 2016 , 53-57

Mekinian A, Grignano E, Braun T, Decaux O, Liozon E, Costedoat-Chalumeau N & al , Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective studyRHEUMATOLOGY, 2016 , 291-300

Sanges S, Launay D, Rhee RL, Sitbon O, Hachulla É, Mouthon L & al , A prospective study of the 6 min walk test as a surrogate marker for haemodynamics in two independent cohorts of treatment-naive systemic sclerosis-associated pulmonary arterial hypertensionAnn. Rheum. Dis., 2016 , 1457-1465

Longhurst HJ, Aberer W, Bouillet L, Caballero T, Fabien V, Zanichelli A & al , Analysis of characteristics associated with reinjection of icatibant: Results from the icatibant outcome survey.Allergy Asthma Proc, 2015 , 399-406

Zaidan M, Terrier B, Pozdzik A, Frouget T, Rioux-Leclercq N, Combe C & al , Spectrum and Prognosis of Noninfectious Renal Mixed Cryoglobulinemic GNJ. Am. Soc. Nephrol., 2016 , 1213-1224

Ingegnoli F, Boracchi P, Gualtierotti R, Smith V, Cutolo M, Foeldvari I & al , A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory studyMicrovasc. Res., 2015 , 19-24

Dutoit-Lefevre V, Dubucquoi S, Launay D, Sobanski V, Dussart P, Chafey P & al , An Optimized Fluorescence-Based Bidimensional Immunoproteomic Approach for Accurate Screening of AutoantibodiesPLoS One, 2015

Hernández Fernandez de Rojas D, Ibañez E, Longhurst H, Maurer M, Fabien V, Aberer W & al , Treatment of HAE Attacks in the Icatibant Outcome Survey: An Analysis of Icatibant Self-Administration versus Administration by Health Care Professionals.Int. Arch. Allergy Immunol., 2015 , 21-8

Benarous L, Terrier B, Puéchal X, Dunogué B, Cohen P, Le Jeunne C & al , Tobacco differentially affects the clinical-biological phenotypes of ANCA-associated vasculitides.Clin. Exp. Rheumatol., 2015 , S-116-21

Hachulla E, Hatron PY, Carpentier P, Agard C, Chatelus E, Jego P & al , Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE studyAnn. Rheum. Dis., 2016 , 1009-1015

Jallouli M, Galicier L, Zahr N, Aumaître O, Francès C, Le Guern V & al , Determinants of Hydroxychloroquine Blood Concentration Variations in Systemic Lupus ErythematosusArthritis Rheumatol., 2015 , 2176-2184

Bouillet L, Lehmann A, Gompel A, Boccon-Gibod I, Launay D, Fain O , Hereditary angioedema treatments: Recommendations from the French national center for angioedema (Bordeaux consensus 2014)Presse Med., 2015 , 526-532

Javaud N, Gompel A, Bouillet L, Boccon-Gibod I, Cantin D, Smaiti N & al , Factors associated with hospital admission in hereditary angioedema attacks: a multicenter prospective studyAnn. Allergy Asthma Immunol., 2015 , 499-503

Strubi-Vuillaume I, Carlier V, Obeuf C, Vasseur F, Maury JC, Maboudou P & al , Gentle blood aspiration and tube cushioning reduce pneumatic tube system interference in lactate dehydrogenase assaysAnn. Clin. Biochem., 2016 , 295-297

Jamet MP, Gnemmi V, Hachulla É, Dhaenens CM, Bouchindhomme B, Delattre C & al , Distinctive Patterns of Transthyretin Amyloid in Salivary Tissue A Clinicopathologic Study of 92 Patients With Amyloid-containing Minor Salivary Gland BiopsiesAm. J. Surg. Pathol., 2015 , 1035-1044

Rochoy M, Gautier S, Bordet R, Caron J, Launay D, Hachulla E & al , Pharmacovigilance center internal medicine interactions: A useful diagnostic toolRev. Med. Interne, 2015 , 516-521

Mihai C, Landewé R, van der Heijde D, Walker UA, Constantin PI, Gherghe AM & al , Digital ulcers predict a worse disease course in patients with systemic sclerosisAnn. Rheum. Dis., 2016 , 681-686

Lefevre G, Copin MC, Roumier C, Aubert H, Avenel-Audran M, Grarde N & al , CD3(-)CD4(+) lymphoid variant of hypereosinophilic syndrome: nodal and extranodal histopathological and immunophenotypic features of a peripheral indolent clonal T-cell lymophoproliferative disorderHaematologica, 2015 , 1086-1095

Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P & al , Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR populationRHEUMATOLOGY, 2015 , 1262-1269

Launay D , Angioedema: Differential diagnosisPresse Med., 2015 , 30-36

Lefevre G, Copin MC, Staumont-Salle D, Avenel-Audran M, Aubert H, Taieb A & al , The Lymphoid Variant of Hypereosinophilic Syndrome Study of 21 Patients With CD3-CD4+ Aberrant T-Cell PhenotypeMedicine (Baltimore), 2014 , 255-266

Schoindre Y, Jallouli M, Tanguy ML, Ghillani P, Galicier L, Aumaître O & al , Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up.Lupus Sci Med, 2014 , e000027

Guillevin L, Pagnoux C, Karras A, Khouatra C, Aumaître O, Cohen P & al , Rituximab versus Azathioprine for Maintenance in ANCA-Associated VasculitisN. Engl. J. Med., 2014 , 1771-1780

Lefevre G, Meyer A, Launay D, Machelart I, DeBandt M, Michaud J & al , Seronegative polyarthritis revealing antisynthetase syndrome: a multicentre study of 40 patientsRHEUMATOLOGY, 2015 , 927-932

Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P & al , A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective studyAnn. Rheum. Dis., 2016 , 163-169

Neel A, Henry B, Barbarot S, Masseau A, Perrin F, Bernier C & al , Long-term effectiveness and safety of interleukin-1 receptor antagonist (anakinra) in Schnitzler's syndrome: A french multicenter studyAutoimmun. Rev., 2014 , 1035-1041

Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G, Carreira PE & al , Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective studyAnn. Rheum. Dis., 2016 , 103-109

Trad S, Nosbaum A, Musset L, Ghillani-Dalbin P, Launay D, Costedoat-Chalumeau N & al , Systemic sclerosis and prevalence of monoclonal immunoglobulinAutoimmun. Rev., 2014 , 1189-1194

Charignon D, Ghannam A, Defendi F, Ponard D, Monnier N, Trascasa ML & al , Hereditary angioedema with F12 mutation: factors modifying the clinical phenotypeAllergy, 2014 , 1659-1665

Lanteri A, Sobanski V, Langlois C, Lefevre G, Hauspie C, Sanges S & al , Serum free light chains of immunoglobulins as biomarkers for systemic sclerosis characteristics, activity and severityAutoimmun. Rev., 2014 , 974-980

van Laar JM, Farge D, Sont JK, Naraghi K, Marjanovic Z, Larghero J & al , Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical TrialJAMA-J. Am. Med. Assoc., 2014 , 2490-2498

Launay D, Savale L, Berezne A, Le Pavec J, Hachulla E, Mouthon L & al , Lung and heart-lung transplantation for systemic sclerosis patients. A monocentric experience of 13 patients, review of the literature and position paper of a multidisciplinary Working GroupPresse Med., 2014 , E345-E363

Maurer B, Graf N, Michel BA, Müller-Ladner U, Czirják L, Denton CP & al , Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database.Ann. Rheum. Dis., 2015 , 1124-31

Wintenberger C, Boccon-Gibod I, Launay D, Fain O, Kanny G, Jeandel PY & al , Tranexamic acid as maintenance treatment for non-histaminergic angioedema: analysis of efficacy and safety in 37 patientsClin. Exp. Immunol., 2014 , 112-117

Gathmann B, Mahlaoui N, Gérard L, Oksenhendler E, Warnatz K, Schulze I & al , Clinical picture and treatment of 2212 patients with common variable immunodeficiency.J. Allergy Clin. Immunol., 2014 , 116-26

Sobanski V, Dauchet L, Lefevre G, Lambert M, Morell-Dubois S, Sy T & al , Prevalence of Anti-RNA Polymerase III Antibodies in Systemic Sclerosis New Data From a French Cohort and a Systematic Review and Meta-AnalysisArthritis Rheumatol., 2014 , 407-417

Heusele M, Clerson P, Guery B, Lambert M, Launay D, Lefevre G & al , Risk factors for severe bacterial infections in patients with systemic autoimmune diseases receiving rituximabClin. Rheumatol., 2014 , 799-805

Damaj G, Joris M, Chandesris O, Hanssens K, Soucie E, Canioni D & al , ASXL1 but Not TET2 Mutations Adversely Impact Overall Survival of Patients Suffering Systemic Mastocytosis with Associated Clonal Hematologic Non-Mast-Cell DiseasesPLoS One, 2014

Terrier B, Marie I, Launay D, Lacraz A, Belenotti P, de St-Martin L & al , Predictors of early relapse in patients with non-infectious mixed cryoglobulinemia vasculitis: Results from the French nationwide CryoVas surveyAutoimmun. Rev., 2014 , 630-634

Mekinian A, Braun T, Decaux O, Falgarone G, Toussirot E, Raffray L & al , Inflammatory Arthritis in Patients With Myelodysplastic Syndromes A Multicenter Retrospective Study and Literature Review of 68 CasesMedicine (Baltimore), 2014 , 1-10

Kasdi R, El Arid JM, Lambert M, Launay D, Polge AS, Koussa M & al , To Spare or Not to Spare ...? The Aortic Valve in Scleroderma and Aortic Root AneurysmJ. Card. Surg., 2014 , 55-58

Sivova N, Launay D, Wemeau-Stervinou L, De Groote P, Remy-Jardin M, Denis G & al , Relevance of Partitioning DLCO to Detect Pulmonary Hypertension in Systemic SclerosisPLoS One, 2013

Jamilloux Y, Magy L, Hurtevent JF, Gondran G, de Seze J, Launay D & al , Immunological profiles determine neurological involvement in Sjogren's syndromeEur. J. Intern. Med., 2014 , 177-181

Goeb V, Ardizzone M, Arnaud L, Avouac J, Baillet A, Belot A & al , Recommendations for using TNF alpha antagonists and French Clinical Practice Guidelines endorsed by the French National Authority for HealthJoint Bone Spine, 2013 , 574-581

Bouillet L, Launay D, Fain O, Boccon-Gibod I, Laurent J, Martin L & al , Hereditary angioedema with C1 inhibitor deficiency: clinical presentation and quality of life of 193 French patientsAnn. Allergy Asthma Immunol., 2013 , 290-294

Defendi F, Charignon D, Ghannam A, Baroso R, Csopaki F, Allegret-Cadet M & al , Enzymatic assays for the diagnosis of bradykinin-dependent angioedema.PLoS ONE, 2013 , e70140

Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D & al , Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry.Clin. Exp. Rheumatol., 2013 , 71-80

Hamoir B, Giroux M, Outteryck O, Launay D, Vermersch P , Mixed connective tissue disease presenting as trigeminal neuropathyActa Neurol. Belg., 2014 , 245-246

Morel N, Bachelot A, Chakhtoura Z, Ghillani-Dalbin P, Amoura Z, Galicier L & al , Study of Anti-Mullerian Hormone and Its Relation to the Subsequent Probability of Pregnancy in 112 Patients With Systemic Lupus Erythematosus, Exposed or Not to CyclophosphamideJ. Clin. Endocrinol. Metab., 2013 , 3785-3792

Jallouli M, Francès C, Piette JC, Huong du LT, Moguelet P, Factor C & al , Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus: a case-control study.JAMA Dermatol, 2013 , 935-40

Lefevre G, Dauchet L, Hachulla E, Montani D, Sobanski V, Lambert M & al , Survival and Prognostic Factors in Systemic Sclerosis-Associated Pulmonary Hypertension: A Systematic Review and Meta-AnalysisArthritis Rheum., 2013 , 2412-2423

Launay D, Dutoit-Lefevre V, Faure E, Robineau O, Hauspie C, Sobanski V & al , Effect of In Vitro and In Vivo Anakinra on Cytokines Production in Schnitzler SyndromePLoS One, 2013

Saule C, Boccon-Gibod I, Fain O, Kanny G, Plu-Bureau G, Martin L & al , Benefits of progestin contraception in non-allergic angioedemaClin. Exp. Allergy, 2013 , 475-482

Rochoy M, Lefeyre G, Fontaine A, Boualit M, Le Roy P, Neugebauer Y & al , Atypical gastritisRev. Med. Interne, 2013 , 581-582

Hervier B, Meyer A, Dieval C, Uzunhan Y, Devilliers H, Launay D & al , Pulmonary hypertension in antisynthetase syndrome: prevalence, aetiology and survivalEur. Resp. J., 2013 , 1271-1282

Nosbaum A, Bouillet L, Floccard B, Javaud N, Launay D, Boccon-Gibod I & al , Management of angiotensin-converting enzyme inhibitor-related angioedema: Recommendations from the French national centre for angioedemaRev. Med. Interne, 2013 , 209-213

Launay D, Sitbon O, Hachulla E, Mouthon L, Gressin V, Rottat L & al , Survival in systemic sclerosis-associated pulmonary arterial hypertension in the modern management eraAnn. Rheum. Dis., 2013 , 1940-1946

Costedoat-Chalumeau N, Galicier L, Aumaître O, Francès C, Le Guern V, Lioté F & al , Hydroxychloroquine in systemic lupus erythematosus: results of a French multicentre controlled trial (PLUS Study)Ann. Rheum. Dis., 2013 , 1786-1792

Forestier A, Lefebvre G, Leroy X, Husson J, Gay J, Leleu X & al , Osteolytic Lesion with Thick Sclerotic Walls and Demyelinating PolyneuropathyJ. Rheumatol., 2012 , 2175-2176

Comarmond C, Pagnoux C, Khellaf M, Cordier JF, Hamidou M, Viallard JF & al , Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohortArthritis Rheum., 2013 , 270-281

Haroche J, Charlotte F, Arnaud L, von Deimling A, Helias-Rodzewicz Z, Hervier B & al , High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytosesBlood, 2012 , 2700-2703

Meier FM, Frommer KW, Dinser R, Walker UA, Czirjak L, Denton CP & al , Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database.Ann. Rheum. Dis., 2012 , 1355-60

Mekinian A, Jaccard A, Soussan M, Launay D, Berthier S, Federici L & al , 18F-FDG PET/CT in patients with amyloid light-chain amyloidosis: case-series and literature reviewAmyloid-J. Protein Fold. Disord., 2012 , 94-98

Terrier B, Carrat F, Krastinova E, Marie I, Launay D, Lacraz A & al , Prognostic factors of survival in patients with non-infectious mixed cryoglobulinaemia vasculitis: data from 242 cases included in the CryoVas surveyAnn. Rheum. Dis., 2013 , 374-380

Lefevre G, Zephir H, Warembourg F, Michelin E, Pruvo JP, Hachulla E & al , Neuropsychiatric systemic lupus erythematosus (1st part). Cases definitions and diagnosis and treatment of central nervous system and psychiatric manifestations of systemic lupus erythematosusRev. Med. Interne, 2012 , 491-502

Lefevre G, Zephir H, Michelin E, Semah F, Warembourg F, Pruvo JP & al , Neuropsychiatric systemic lupus erythematosus (2nd part). Diagnostic and treatment tools in psychiatric or central nervous system manifestations in systemic lupus erythematosusRev. Med. Interne, 2012 , 503-513

Terrier B, Krastinova E, Marie I, Launay D, Lacraz A, Belenotti P & al , Management of noninfectious mixed cryoglobulinemia vasculitis: data from 242 cases included in the CryoVas surveyBlood, 2012 , 5996-6004

Hannebicque-Montaigne K, Le Roc'h A, Launay D, Coulon C, Deruelle P, Langlois S , Haemophagocytic syndrome in pregnancy: A case reportAnn. Fr. Anest. Reanim., 2012 , 239-242

Denton CP, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Silkey M & al , Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.Ann. Rheum. Dis., 2012 , 718-21

Aouba A, Bienvenu B, Launay D, Hermine O , Role of Iconographic Examinations in the Treatment Algorithm in Erdheim-Chester DiseaseJ. Clin. Oncol., 2011 , 4466-4467

Mekinian A, Ravaud P, Hatron PY, Larroche C, Leone J, Gombert B & al , Efficacy of rituximab in primary Sjogren's syndrome with peripheral nervous system involvement: results from the AIR registryAnn. Rheum. Dis., 2012 , 84-87

Broucqsault A, Ouzzane A, Launay D, Leroy X, Rose C, Villers A & al , Renal extramedullary hematopoiesisProg. Urol., 2011 , 575-579

Humbert M, Yaici A, de Groote P, Montani D, Sitbon O, Launay D & al , Screening for Pulmonary Arterial Hypertension in Patients With Systemic Sclerosis Clinical Characteristics at Diagnosis and Long-Term SurvivalArthritis Rheum., 2011 , 3522-3530

Martel C, Gondran G, Launay D, Lalloue F, Palat S, Lambert M & al , Active Immunological Profile Is Associated with Systemic Sjogren's SyndromeJ. Clin. Immunol., 2011 , 840-847

Stavris C, Lambert M, Lefevre G, Mirault T, Pape E, Buchdahl-Duchange AL & al , Clinical case of the Spring if Internal Medicine Bernard Debulder Day Any part of Greenwich Weight loss and dyspnea in a 46-year-old womanRev. Med. Interne, 2011 , 447-450

Daikeler T, Labopin M, Di Gioia M, Abinun M, Alexander T, Miniati I & al , Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working PartyBlood, 2011 , 1693-1698

Distler JHW, Jordan S, Airo P, Alegre-Sancho JJ, Allanore Y, Gurman AB & al , Is there a role for TNF-alpha antagonists in the treatment of SSc? EUSTAR expert consensus development using the Delphi techniqueClin. Exp. Rheumatol., 2011 , S40-S45

Lefevre G, Lambert M, Bacri JL, Dubucquoi S, Quemeneur T, Caron C & al , Thrombotic events during long-term follow-up of obstetric antiphospholipid syndrome patientsLupus, 2011 , 861-865

Le Pavec J, Girgis RE, Lechtzin N, Mathai SC, Launay D, Hummers LK & al , Systemic Sclerosis-Related Pulmonary Hypertension Associated With Interstitial Lung Disease Impact of Pulmonary Arterial Hypertension TherapiesArthritis Rheum., 2011 , 2456-2464

Hachulla E, Launay D, Le Pavec J, Mouthon L, Guillevin L, de Groote P , [Systemic sclerosis associated pulmonary arterial hypertension: the pitfalls].Presse Med, 2011 , 1S46-53

Launay D, Humbert M, Berezne A, Cottin V, Allanore Y, Couderc LJ & al , Clinical Characteristics and Survival in Systemic Sclerosis-Related Pulmonary Hypertension Associated With Interstitial Lung DiseaseChest, 2011 , 1016-1024

Morell-Dubois S, Condette-Wojtasik G, Clerson P, Berezne A, Launay D, Lambert M & al , Complaints, needs of patients with systemic sclerosis: A better understanding for a better careRev. Med. Interne, 2011 , 537-543

Bloch J, Morell-Dubois S, Koch E, Launay D, Maillard-Lefebvre H, Buchdahl AL & al , [Visual hallucinations and giant cell arteritis: the Charles Bonnet syndrome].Rev Med Interne, 2011 , e119-21

Mekinian A, Durand-Joly I, Hatron PY, Moranne O, Denis G, Dei-Cas E & al , Pneumocystis jirovecii colonization in patients with systemic autoimmune diseases: prevalence, risk factors of colonization and outcomeRHEUMATOLOGY, 2011 , 569-577

Mekinian A, Lions C, Leleu X, Duhamel A, Lamblin N, Coiteux V & al , Prognosis Assessment of Cardiac Involvement in Systemic AL Amyloidosis by Magnetic Resonance ImagingAm. J. Med., 2010 , 864-868

Terrier B, Launay D, Kaplanski G, Hot A, Larroche C, Cathebras P & al , Safety and Efficacy of Rituximab in Nonviral Cryoglobulinemia Vasculitis: Data From the French AutoImmunity and Rituximab RegistryArthritis Care Res., 2010 , 1787-1795

de Groote P, Lamblin N, Launay D, Bervar JF, Hachulla E , Screening and diagnosis of pulmonary arterial hypertension. Comments regarding the latest guidelines from the European Societies of Cardiology and of PulmonologyPresse Med., 2010 , 1S16-1S21

Ranque B, Berezne A, Le-Guern V, Pagnoux C, Allanore Y, Launay D & al , Myopathies related to systemic sclerosis: a case-control study of associated clinical and immunological featuresScand. J. Rheumatol., 2010 , 498-505

Avouac J, Walker U, Tyndall A, Kahan A, Matucci-Cerinic M, Allanore Y & al , Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database.J. Rheumatol., 2010 , 1488-501

Fauchais AL, Martel C, Gondran G, Lambert M, Launay D, Jauberteau MO & al , Immunological profile in primary Sjogren syndrome Clinical significance, prognosis and long-term evolution to other auto-immune diseaseAutoimmun. Rev., 2010 , 595-599

Launay D, Schmidt J, Lepers S, Mirault T, Lambert M, Kyndt X & al , Comparison of the Farr radioimmunoassay, 3 commercial enzyme immunoassays and Crithidia luciliae immunofluorescence test for diagnosis and activity assessment of systemic lupus erythematosusClin. Chim. Acta, 2010 , 959-964

Fauchais AL, Ouattara B, Gondran G, Lalloue F, Petit D, Ly K & al , Articular manifestations in primary Sjogren's syndrome: clinical significance and prognosis of 188 patientsRHEUMATOLOGY, 2010 , 1164-1172

Hachulla E, Launay D, Yaici A, Berezne A, de Groote P, Sitbon O & al , Pulmonary arterial hypertension associated with systemic sclerosis in patients with functional class II dyspnoea: mild symptoms but severe outcomeRHEUMATOLOGY, 2010 , 940-944

Hachulla E, Launay D , Diagnosis and Classification of Systemic SclerosisClin. Rev. Allergy Immunol., 2011 , 78-83

Pagnoux C, Seror R, Henegar C, Mahr A, Cohen P, Le Guern V & al , Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database.Arthritis Rheum., 2010 , 616-26

Maillard-Lefebvre H, Morell-Dubois S, Lambert M, Charlanne H, Launay D, Hachulla E & al , Graft-versus-host disease-related polymyositisClin. Rheumatol., 2010 , 431-433

Launay D, Baubet T, Cottencin O, Berezne A, Zephir H, Morell-Dubois S & al , Neuropsychiatric manifestations in systemic sclerosisPresse Med., 2010 , 539-547

Le Pavec J, Launay D, Mathai SC, Hassoun PM, Humbert M , Scleroderma Lung DiseaseClin. Rev. Allergy Immunol., 2011 , 104-116

Mekinian A, Queyrel V, Durand-Joly I, Moranne O, Denis G, Delhaes L & al , Positive Pneumocystis jirovecii PCR in immunocompromised patients with a systemic disease: Infection or colonisation?Rev. Med. Interne, 2010 , 194-199

Launay D, Sitbon O, Le Pavec J, Savale L, Tcherakian C, Yaici A & al , Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafilRHEUMATOLOGY, 2010 , 490-500

Guiheneuf R, Vuillaume I, Mangalaboyi J, Launay D, Berthon C, Maury JC & al , Pneumatic transport is critical for leukaemic patients with major leukocytosis: what precautions to measure lactate dehydrogenase, potassium and aspartate aminotransferase?Ann. Clin. Biochem., 2010 , 94-96

de Coppet H, Lambert M, Charlanne H, Launay D, Morell-Dubois S, Maillard-Lefebvre H & al , Superficial cranial venous thromboses preceding the diagnosis of giant cell arteritisJ. Mal. Vasc., 2010 , 23-25

Lefevre G, Queyrel V, Maurage CA, Laurent C, Launay D, Lacour A & al , Effective immune restoration after immunosuppressant discontinuation in a lupus patient presenting progressive multifocal leukoencephalopathyJ. Neurol. Sci., 2009 , 246-249

Declerck L, Queyrel V, Morell-Dubois S, Dewilde A, Charlanne H, Launay D & al , Cytomegalovirus and systemic lupus: Severe infection and difficult diagnosisRev. Med. Interne, 2009 , 789-793

Monsarrat N, Houfflin-Debarge V, Richard A, Launay D, Lambert M, Hatron PY & al , Fetal ultrasonography and Doppler in isolated congenital heart blockGynecol. Obstet. Fertil., 2009 , 633-644

Mekinian A, Lambert M, Beregi JP, Morell-Dubois S, Launay D, Queyrel V & al , Aortic aneurysm in MAGIC syndrome successfully managed with combined anti-TNF-alpha and stent graftingRHEUMATOLOGY, 2009 , 1169-1170

Launay D, Marjanovic Z, de Bazelaire C, Florea L, Zohar S, Keshtmand H & al , Autologous Hematopoietic Stem Cell Transplant in Systemic Sclerosis: Quantitative High Resolution Computed Tomography of the Chest ScoringJ. Rheumatol., 2009 , 1460-1463

Hachulla E, de Groote P, Gressin V, Sibilia J, Diot E, Carpentier P & al , The Three-Year Incidence of Pulmonary Arterial Hypertension Associated With Systemic Sclerosis in a Multicenter Nationwide Longitudinal Study in FranceArthritis Rheum., 2009 , 1831-1839

Hachulla E, Launay D, Mouthon L, Sitbon O, Berezne A, Guillevin L & al , Is Pulmonary Arterial Hypertension Really a Late Complication of Systemic Sclerosis?Chest, 2009 , 1211-1219

Verrecchia F, Michel L, Keshtmand H, Wang Y, Launay D, Farge D , Do specific antifibrotic properties of immunosuppressive drugs used in the treatment of systemic sclerosis exist?Rev. Med. Interne, 2009 , 955-962

Hornez N, Morell-Dubois S, Woillez JP, Queyrel V, Charlanne H, Launay D & al , Euthyroid Graves' disease: A case reportRev. Med. Interne, 2009 , 988-990

Rak JM, Pagni PP, Tiev K, Allanore Y, Farge D, Harle JR & al , Male microchimerism and HLA compatibility in French women with sclerodema: a different profile in limited and diffuse subsetRHEUMATOLOGY, 2009 , 363-366

Hachulla E, Bervar JF, Launay D, Lamblin N, Perez T, Mouthon L & al , Dyspnea on exertion in scleroderma: from symptom to diagnosisPresse Med., 2009 , 911-926

Hachulla E, Carpentier P, Gressin V, Diot E, Allanore Y, Sibilia J & al , Risk factors for death and the 3-year survival of patients with systemic sclerosis: the French ItinrAIR-Sclrodermie studyRHEUMATOLOGY, 2009 , 304-308

Pagnoux C, Mahr A, Hamidou MA, Boffa JJ, Ruivard M, Ducroix JP & al , Azathioprine or Methotrexate Maintenance for ANCA-Associated Vasculitis.N. Engl. J. Med., 2008 , 2790-2803

Hachulla AL, Launay D, Gaxotte V, de Groote P, Lamblin N, Devos P & al , Cardiac magnetic resonance imaging in systemic sclerosis: a cross-sectional observational study of 52 patientsAnn. Rheum. Dis., 2009 , 1878-1884

Ranque B, Authier FJ, Le-Guern V, Pagnoux C, Berezne A, Allanore Y & al , A descriptive and prognostic study of systemic sclerosis-associated myopathiesAnn. Rheum. Dis., 2009 , 1474-1477

Maillard-Lefebvre H, Queyrel V, Lambert M, Hachulla E, Launay D, Morell-Dubois S & al , Abdominal pain in a 22-year-old womanRev. Med. Interne, 2008 , 754-757

Gondran G, Fauchais AL, Lambert M, Ly K, Launay D, Queyrel V & al , Primary Sjogren's syndrome in menScand. J. Rheumatol., 2008 , 300-305

Mekinian A, Lambert M, Queyrel V, Launay D, Morell-Dubois S, Hachulla E & al , Adult-onset Still's disease and hepatic angiosarcoma, a fortuitous association or a paraneoplastic syndrome: A case-reportRev. Med. Interne, 2008 , 936-939

Lambert M, Launay D, Hachulla E, Morell-Dubois S, Soland V, Queyrel V & al , High-dose intravenous immunoglobulins dyamatically reverse systemic capillary leak syndromeCrit. Care Med., 2008 , 2184-2187

Maillard-Lefebvre H, Launay D, Mouquet F, Gaxotte V, Hachulla E, de Groote P & al , Polyarteritis nodosa-related coronary aneurysmsJ. Rheumatol., 2008 , 933-934

Berezne A, Ranque B, Valeyre D, Brauner M, Allanore Y, Launay D & al , Therapeutic strategy combining intravenous cyclophosphamide followed by oral azathioprine to treat worsening interstitial lung disease associated with systemic sclerosis: A retrospective multicenter open-label studyJ. Rheumatol., 2008 , 1064-1072

Edme JL, Tellart AS, Launay D, Neviere R, Grutzmacher C, Boulenguez C & al , Cytokine concentrations in exhaled breath condensates in systemic sclerosisInflamm. Res., 2008 , 151-156

Jais X, Launay D, Yaici A, Le Pavec J, Tcherakian C, Sitbon O & al , Immunosuppressive therapy in lupus- and mixed connective tissue disease-associated pulmonary arterial hypertensionArthritis Rheum., 2008 , 521-531

Bosman T, Simonin C, Launay D, Caron S, Destee A, Defebvre L , Idiopathic hypertrophic cranial pachymeningitis treated by oral methotrexate: a case report and review of literatureRheumatol. Int., 2008 , 713-718

Hereng T, Lambert M, Hachulla E, Samor M, Dubucquoi S, Caron C & al , Influence of aspirin on the clinical outcomes of 103 anti-phospholipid antibodies-positive patientsLupus, 2008 , 11-15

Launay D, Souza R, Guillevin L, Hachulla E, Pouchot J, Simonneau G & al , Pulmonary arterial hypertension in ANCA-associated vasculitisSarcoidosis Vasc. Diffus. Lung Dis., 2006 , 223-228

Hachulla E, Launay D, Hatron PY , Iloprost for the treatment of systemic sclerosisPresse Med., 2008 , 831-839

Crinquette C, de Seze J, Maurage CA, Launay D, Ferriby D, Delalande S & al , Polymyositis and cranial neuropathyRev. Neurol., 2007 , 1075-1081

Outteryck O, Stojkovic T, Launay D, Meignie-Ramon B, Vermersch P , Periorbital ecchymoses are not pathognomonic of the light-chain type of amyloidosisActa Derm.-Venereol., 2007 , 544-545

Lefranc D, Launay D, Dubucquoi S, de Seze J, Dussart P, Vermersch M & al , Characterization of discriminant human brain antigenic targets in neuropsychiatric systemic lupus erythematosus using an immunoproteomic approachArthritis Rheum., 2007 , 3420-3432

Launay D, Hachulla E, Hatron PY, Jais X, Simonneau G, Humbert M , Pulmonary arterial hypertension: A rare complication of primary Sjogren syndrome - Report of 9 new cases and review of the literatureMedicine (Baltimore), 2007 , 299-315

Cottencin O, Lambert M, Queyrel V, Launay D, Morell-Dubois S, Hachulla E & al , Consultation/liaison psychiatry practice: Combined medical and psychiatric consultationsJ. Psychosomat. Res., 2007 , 219-220

Ludikhuize J, de Launay D, Groot D, Smeets TJ, Vinkenoog M, Sanders ME & al , Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue.Arthritis Rheum., 2007 , 2180-91

Launay D, Mouthon L, Hachulla E, Pagnoux C, de Groote P, Remy-Jardin M & al , Prevalence and characteristics of moderate to severe pulmonary hypertension in systemic sclerosis with and without interstitial lung diseaseJ. Rheumatol., 2007 , 1005-1011

Vuotto F, Queyrel V, Lambert M, Morell-Dubois S, Launay D, Hachulla E & al , MPO-ANCA related vasculitis presenting as chronic iron deficiency anemia due to paucisymptornatic intra-alveolar haemorrhageRev. Med. Interne, 2007 , 484-487

Schmidt J, Launay D, Soudan B, Hachulla E, de Groote P, Lambert M & al , Assessment of plasma endothelin level measurement in systemic sclerosisRev. Med. Interne, 2007 , 371-376

Morell-Dubois S, Quemeneur T, Bourdon F, Lambert M, Queyrel V, Launay D & al , Central retinal artery occlusion in Wegener' granulomatosisRev. Med. Interne, 2007 , 33-37

Launay D, Humbert M, Hachulla E , Pulmonary arterial hypertension and systemic sclerosisPresse Med., 2006 , 1929-1937

Launay D, Lambert M, Hachulla E, De Groote P, Remy-Jardin M, Queyrel V & al , Protein-losing enteropathy revealing an idiopathic constrictive pericarditisRev. Med. Interne, 2007 , 38-41

Launay D , Pulmonary hypertension, the "bete noire" of systemic diseases: from systemic sclerosis to hereditary hemorrhagic telangiectasiaRev. Med. Interne, 2006 , 899-902

Launay D, Remy-Jardin M, Michon-Pasturel U, Mastora I, Hachulla E, Lambert M & al , High resolution computed tomography in fibrosing alveolitis associated with systemic sclerosisJ. Rheumatol., 2006 , 1789-1801

Foguem C, Launay D, Lambert M, Quemeneur T, Hachulla E, Wallaert B & al , Cystic lung disease associated with Sjogren's syndrome: 2 casesRev. Med. Interne, 2006 , 620-624

Quemeneur T, Hachulla E, Lambert M, Perez-Cousin M, Queyrel V, Launay D & al , Takayasu arteritisPresse Med., 2006 , 847-856

Mirault T, Launay D, Cuisset L, Hachulla E, Lambert M, Queyrel V & al , Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinraArthritis Rheum., 2006 , 1697-1700

Launay D, Diot E, Pasquier E, Mouthon L, Boullanger N, Fain O & al , Bosentan for treatment of active digital ulcers in patients with systemic sclerosisPresse Med., 2006 , 587-592

Lavogiez C, Quemeneur T, Hachulla E, Huglo D, Launay D, Lambert M & al , (18)FDG PET: a new criterion for disease activity in Takayasu arteritisRev. Med. Interne, 2006 , 478-481

Morell S, Lambert M, Queyrel V, Launay D, Quemeneur T, Hachulla E & al , Tubercular adenitis and Evans' syndromeLupus, 2006 , 114-115

Maillard H, Launay D, Hachulla E, Goudemand J, Lambert M, Morell-Dubois S & al , Rituximab in postpartum-related acquired hemophiliaAm. J. Med., 2006 , 86-88

Vermersch P, Dufourd-Delalande S, Defoort-Dhellemmes S, Stojkovic T, Launay D, de Seze J , Tonic pupils in Sjogren's syndrome.Rev. Neurol., 2005 , 963-966

Hachulla E, Gressin V, Guillevin L, Carpentier P, Diot E, Sibilia J & al , Early detection of pulmonary arterial hypertension in systemic sclerosis - A French nationwide prospective multicenter studyArthritis Rheum., 2005 , 3792-3800

Launay D, Copin MC, Hachulla E, Lambert M, Quemeneur T, Morell S & al , An amylose that declonesRev. Med. Interne, 2005 , S294-S295

Portal C, Launay D, Merritt A, Bradley M , High throughput physical organic chemistry: Analytical constructs for monomer reactivity profilingJ. Comb. Chem., 2005 , 554-560

Toledano C, Henegar C, Ilie D, Launay D, Tiev K, Marie I & al , Cardiopulmonary function before and after cyclophosphamide treatment in severe systemic sclerosis: comparison of monthly intravenous bolus and autologous haematopoietic stem cell transplantationRev. Med. Interne, 2005 , 444-452

Launay D, Le Berre R, Hatron PY, Peyrat JP, Hachulla E, Devulder B & al , Association between systemic sclerosis and breast cancer: eight new cases and review of the literatureClin. Rheumatol., 2004 , 516-522

Launay A, Hachulla E , Inflammatory aortitisPresse Med., 2004 , 1334-1340

Brenuchon C, Launay D, Maurage CA, Queyrel V, Lambert M, N'Guyen HD & al , Hypertrophic myopathy due to muscular metastasis of a signet cell adenocarcinoma of the bladderRev. Med. Interne, 2004 , 839-841

Charlanne H, Hatron PY, Zerbib P, Lambert M, Launay D, Queyrel V & al , Tuberculous cold abscessesRev. Med. Interne, 2004 , S244-S246

Brenuchon C, Lemoux O, Queyrel V, Launay D, Lambert M, Hachulla E & al , [It is always necessary to ask the girl's hand to her father...].Rev Med Interne, 2004 , S215-7

Charlanne H, Lambert M, Hachulla E, Launay D, Queyrel V, Hatron PY & al , Large granular lymphocyte leukaemia associated with systemic sclerosisRHEUMATOLOGY, 2004 , 1197-1198

Fauchais AL, Lambert M, Launay D, Michon-Pasturel U, Queyrel V, Nguyen N & al , Antiphospholipid antibodies in primary Sjogren's syndrome: prevalence and clinical significance in a series of 74 patientsLupus, 2004 , 245-248

LAMBERT M, FAUCHAIS AL, DUBUCQUOI S, LAUNAY D, CARON C, PRIN L & al , [Influence of hypergammaglobulinemia on antiphospholipid antibodies titres].Rev Med Interne, 2004 , 111-4

Launay D, Peyrat JP, Verdiere A, Hornez L, Hatron PY, Hachulla E & al , Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosisJ. Rheumatol., 2004 , 88-95

Launay D, Thomas C, Fleury D, Roueff S, Line ML, Droz D & al , Pulmonary-renal syndrome due to hemorrhagic fever with renal syndrome: an unusual manifestation of Puumala virus infection in FranceClin. Nephrol., 2003 , 297-300

Eulry F, Diamano J, Launay D, Tabache F, Lechevalier D, Magnin J , Sausage-like toe and heel pain: value for diagnosing and evaluating the severity of spondyloarthropathies defined by Amor's criteria. A retrospective study in 161 patientsJoint Bone Spine, 2002 , 574-579

LAUNAY D, HACHULLA E , [Cardiac and pulmonary involvement in scleroderma].Rev Prat, 2002 , 1901-7

Launay D, Catteau B, Dubost-Brama A, Capron M, Piette F, Delaporte E , A four-year history of pruriginous erythroderma leading to the diagnosis of idiopathic hypereosinophilic syndromeActa Derm.-Venereol., 2002 , 376-378

Launay D, Hebbar M, Valat AS, Ducloy AS, Hachulla E, Hatron PY & al , Systemic sclerosis and pregnancy.Rev. Med. Interne, 2002 , 607-621

Aractingi S, Sibilia J, Meignin V, Launay D, Hachulla E, Le Danff C & al , Presence of microchimerism in labial salivary glands in systemic sclerosis but not in Sjogren's syndromeArthritis Rheum., 2002 , 1039-1043

Launay D, Hatron PY, Queyrel V, Leteurtre E, Beaulieu S, Lemann M & al , A rare association: peliosis hepatis and Crohn's disease.Rev. Med. Interne, 2002 , 198-202

LAUNAY D , [Hematopoietic stem cell transplantation in the treatment of severe autoimmune diseases].Rev Med Interne, 2001 , 1138

LAUNAY D , [Diagnosis of cardiac sarcoidosis and evaluation of the effects of corticosteroid therapy by gadolinium-DTPA-enhanced MRI].Rev Med Interne, 2001 , 1137-8

Vanhille P, Binaut R, Kyndt X, Launay D, Thomas C, Fleury D , Haemorrhagic fever with renal syndromeNephrologie, 2001 , 301-305

Launay D, Queyrel V, Hatron PY, Michon-Pasturel U, Hachulla E, Devulder B , Digital necrosis in a patient with anorexia nervosa caused by vasculopathy and radial artery injuryPresse Med., 2000 , 1850-1852

Launay D, Hachulla E, Hatron PY, Goullard L, Onimus T, Robin S & al , Aerosolized iloprost in CREST syndrome related pulmonary hypertensionJ. Rheumatol., 2001 , 2252-2256

Launay D, Hachulla E, Hatron PY, Michon-Pasturel U, Hebbar M, Queyrel V & al , Pulmonary hypertension screening in systemic sclerosis: apropos 67 patients.Rev. Med. Interne, 2001 , 819-829

Queyrel V, Catteau B, Michon-Pasturel U, Fauchais AL, Delcey V, Launay D & al , DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome: description of two cases after administration of carbamazepine and sulfasalazine.Rev. Med. Interne, 2001 , 582-586

Launay D, Hebbar M, Hatron PY, Michon-Pasturel U, Queyrel V, Hachulla E & al , Relationship between parity and clinical and biological features in patients with systemic sclerosisJ. Rheumatol., 2001 , 509-513

Launay D, Hatron PY, Delaporte E, Hachulla E, Devulder B, Piette F , Scleromyxedema (lichen myxedematosus) associated with dermatomyositisBr. J. Dermatol., 2001 , 359-362

Launay D, Delaporte E, Gillot JM, Janin A, Hachulla E , An unusual cause of vascular purpura: Recurrent cutaneous eosinophilic necrotizing vasculitisActa Derm.-Venereol., 2000 , 394-395

Launay D, Queyrel V, Hatron PY, Michon-Pasturel U, Caron J, Hachulla E & al , Mianserin-induced agranulocytosis: a worrying complication in elderly patientsRev. Med. Interne, 2000 , 642-643

Kyndt X, Launay D, Hebbar M, Hatron PY, Fournier C, Michon-Pasturel U & al , Influence of age on the clinical and biological features of systemic sclerosisRev. Med. Interne, 1999 , 1088-1092

Launay D, Michon-Pasturel U, Boumbar Y, Dubrulle F, Bouroz-Joly J, Hachulla E & al , Spontaneous bilateral perirenal hematoma: an unusual complication of polyarteritis nodosa.Rev. Med. Interne, 1998 , 666-669

Launay D, Hebbar M, Janin A, Hachulla E, Hatron PY, Devulder B , Primary biliary cirrhosis and systemic sclerosis (Reynolds' syndrome): eight new cases. Interest of the labial salivary gland biopsy.Rev. Med. Interne, 1998 , 393-398

Launay D, Hebbar M, Louyot J, Hachulla E, Hatron PY, Devulder B , Association between yellow nail syndrome and rheumatoid arthritis. Regression with chrysotherapyRev. Med. Interne, 1997 , 494-496

Launay D , Interstitial lung disease and systemic sclerosisRev. Med. Interne, 2016 , A16-A21

Launay D , New management option for hereditary angioedema: Firazyr (R) (icatibant)-58th meeting of the French national society of internal medicine, Bordeaux, 2008 December 12thRev. Med. Interne, 2009 , 384-386

Launay D , Sixtieth Congress of the French National Society of Internal Medicine and Franco-Maghrebi Fourth Congress of Internal Medicine (Toulouse, 9-12 December 2009): highlightsRev. Med. Interne, 2010 , 1-2

Launay D , Track and early diagnosis of pulmonary hypertension and connective: What impact on the expected evolution of the disease?Rev. Med. Interne, 2010 , 3-7

Launay D , therapeutic interest of an inhibitor of phosphodiesterase type 5 and a selective endothelin A receptorRev. Med. Interne, 2010 , 8-9

Launay D , New European guidelines for early and specific treatment of combination therapy: What implications for practice?Rev. Med. Interne, 2010 , 10-13

Hachulla E, Launay D, Clerson P, Humbert M , Is Pulmonary Arterial Hypertension Really a Late Complication of Systemic Sclerosis? ResponseChest, 2010 , 462-463

Hachulla E, Launay D, Le Pavec J, Mouthon L, Guillevin L, de Groote P , Systemic sclerosis associated pulmonary arterial hypertension: the pitfallsPresse Med., 2011 , 46-53

Montante A, Le Bras A, Pagnoux C, Perrodeau E, Ravaud P, Terrier B & al , Cost-effectiveness of rituximab versus azathioprine for maintenance treatment in antineutrophil cytoplasmic antibody-associated vasculitisClin. Exp. Rheumatol., 2019 , S137-S143

Launay D, Zephir H, Hatron PY , A Scleroderma Patient Presenting with Facial Pain-, 2011 , 293-298

Hachulla E, Launay D, Humbert M , Bosentan for the treatment of pulmonary arterial hypertension associated to sclerodermaRev. Med. Interne, 2007 , S221-S226

Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D & al , Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO RegistryClin. Exp. Rheumatol., 2013 , S71-S80

Launay D , Which work-up for which mastocytosis?Rev. Fr. Allergol., 2014 , 134-136

Launay D , News of 70th Congress of the French National Society of Internal Medicine Paris, from 10 to 12 December 2014Rev. Med. Interne, 2015 , S1-S10

Bertolino J, Jouve E, Skopinski S, Agard C, Achille A, Thoreau B & al , Characteristics of patients with systemic sclerosis suffering from a lower limb amputation: Results of a French collaborative studyJ. Scleroderma Relat. Disord., 2020

Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao LD, Harb S & al , Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patientsJ. Psychosomat. Res., 2020

Launay D, Vanhille P , Acute non-cardiogenic pulmonary edema in a 2003 French Puumala virus case: cautions and corrections - ReplyClin. Nephrol., 2004 , 366-366

Launay D, Booth S, Clemens I, Merritt A, Bradley M , Solid phase-mediated synthesis of isonitrilesTetrahedron Lett., 2002 , 7201-7203

Launay D , What's new in allergy: Internal medicineRev. Fr. Allergol., 2015 , 207-209

Lambert M, Launay D, Hachulla E, Morell-Dubois S, Queyrel V, Hatron PY & al , Beneficial effect of intravenous immunoglobulins on systemic capillary leak syndrome in patients with monoclonal gammopathy ReplyCrit. Care Med., 2009 , 795-795